Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RB12599Conserved hypothetical protein-putative flavoprotein; PMID: 10567266 best DB hits: BLAST: pir:A75455; hypothetical protein - Deinococcus radiodurans (strain; E=2e-16 ddbj:BAB13746.1; (AB032601) azoreductase [Bacillus sp. OY1-2]; E=2e-05 gb:AAD13563.1; (AF080235) reductase homolog [Streptomyces; E=5e-04 COG: BH2050; COG0431 Predicted flavoprotein; E=6e-05. (177 aa)    
Predicted Functional Partners:
cdsA
Phosphatidate cytidylyltransferase; PMID: 2995358 PMID: 2995359 best DB hits: BLAST: gb:AAK04086.1; (AE006236) unknown [Pasteurella multocida]; E=7e-53 pir:A83329; probable phosphatidate cytidylyltransferase PA2536; E=2e-51 pir:H82138; probable phosphatidate cytidylyltransferase VC1936; E=2e-32 COG: PA2536; COG0575 CDP-diglyceride synthetase; E=2e-52 PFAM: PF01148; Phosphatidate cytidylyltransf; E=5.5e-08.
       0.586
RB9585
Bac_luciferase domain-containing protein; Best DB hits: BLAST: pir:E83496; hypothetical protein PA1186 [imported] - Pseudomonas; E=8e-50 embl:CAB76875.1; (AL159139) hypothetical protein SCL6.10; E=2e-12 swissprot:P71557; Y953_MYCTU HYPOTHETICAL 30.9 KDA PROTEIN RV0953C; E=7e-08 COG: PA1186; COG2141 Coenzyme F420-dependent N5,N10-methylene; E=8e-51 PFAM: PF00296; Bacterial luciferase; E=0.86.
  
 
 0.505
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
       0.425
RB6716
Transport protein-putative arsenite transport; PMID: 1535622 best DB hits: BLAST: pir:F71205; hypothetical protein PH1912 - Pyrococcus horikoshii; E=3e-37 pir:F72315; conserved hypothetical protein - Thermotoga maritima; E=4e-37 pir:C75019; transport protein PAB1107 - Pyrococcus abyssi (strain; E=3e-36 COG: PH1912; COG1055 Na+/H+ antiporter NhaD and related arsenite; E=3e-38 arsB; COG1055 Na+/H+ antiporter NhaD and related arsenite permeases; E=6e-14 BH2999; COG1055 Na+/H+ antiporter NhaD and related arsenite; E=4e-13.
  
  
 0.412
arsC-2
Arsenate reductase; PMID: 8674982 best DB hits: BLAST: pir:C81247; arsenate reductase NMB0005 [imported] - Neisseria; E=8e-26 gb:AAG57605.1; AE005479_3 (AE005479) putative oxidoreductase; E=6e-25 swissprot:P76569; YFGD_ECOLI PROTEIN YFGD ----- pir: F65025; E=6e-25 COG: NMB0005; COG1393 Arsenate reductase and related proteins,; E=8e-27 yfgD; COG1393 Arsenate reductase and related proteins, glutaredoxin; E=7e-26 VC2165; COG1393 Arsenate reductase and related proteins,; E=3e-25; Belongs to the ArsC family.
  
  
 0.410
RB783
Probable integral membrane efflux protein; Best DB hits: BLAST: swissprot:P74311; Y944_SYNY3 HYPOTHETICAL 42.4 KDA PROTEIN SLR0944; E=2e-86 pir:H81780; probable integral membrane efflux protein NMA2095; E=3e-47 gb:AAK04027.1; (AE006231) unknown [Pasteurella multocida]; E=7e-40 COG: slr0944; COG0798 Arsenite efflux pump ACR3 and related permeases; E=2e-87 PFAM: PF01758; Sodium Bile acid symporter family; E=7.8e-49.
     
 0.405
nrtC
Nitrate transport ATP-binding protein; PMID: 9495773 PMID: 8437564 best DB hits: BLAST: swissprot:P73450; NRTC_SYNY3 NITRATE TRANSPORT ATP-BINDING PROTEIN; E=3e-61 gb:AAB86900.1; (L27431) nitrate transporter component; NasF; E=2e-51 pir:S75959; nitrate transport protein C-1 - Synechocystis sp; E=6e-49 COG: sll1452_2; COG0715 ABC-type nitrate/sulfonate/taurine/bicarbonate; E=3e-62.
  
  
 0.404
RB7287
Conserved hypothetical protein-putative permease protein of ABC transporter; PMID: 11214968 best DB hits: BLAST: pir:C72369; hypothetical protein TM0484 - Thermotoga maritima; E=6e-08 ddbj:BAB06401.1; (AP001516) thiamine biosynthesis [Bacillus; E=0.009 pir:H72008; ABC transporter permease - Chlamydophila pneumoniae; E=0.42 COG: TM0484; COG0715 ABC-type nitrate/sulfonate/taurine/bicarbonate; E=6e-09.
  
  
 0.404
noxA
Probable NADH oxidase; Best DB hits: BLAST: pir:B82434; probable NADH oxidase VCA0644 [imported] - Vibrio; E=1e-102 gb:AAK04884.1; AE006312_4 (AE006312) NADH oxidase [Lactococcus; E=3e-99 gb:AAB90837.1; (AE001077) NADH oxidase (noxA-3) [Archaeoglobus; E=2e-75 COG: VCA0644_1; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; E=5e-87 BH0613; COG1251 NAD(P)H-nitrite reductase; E=1e-18 PFAM: PF01266; D-amino acid oxidase; E=0.47 PF02032; Phytoene dehydrogenase related; E=0.14 PF00070; Pyridine nucleotide-disulphide; E=8.8e-72.
     
 0.402
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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