STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB12612Hypothetical protein. (79 aa)    
Predicted Functional Partners:
RB12610
Hypothetical protein.
       0.773
RB12611
Probable methyltransferase; Best DB hits: BLAST: pir:S75267; hypothetical protein slr1039 - Synechocystis sp. (strain; E=5e-07 swissprot:P46326; YXBB_BACSU HYPOTHETICAL 28.2 KDA PROTEIN IN; E=7e-06 gb:AAG29793.1; AF235050_16 (AF235050) putative methyltransferase; E=0.005 COG: slr1039; COG0500 SAM-dependent methyltransferases; E=5e-08 VC1257; COG2227; E=9e-04 BH2331; COG0500 SAM-dependent methyltransferases; E=0.001.
       0.773
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.773
RB12608
Uncharacterized protein; PMID: 10984043 best DB hits: BLAST: pir:D83367; hypothetical protein PA2235 [imported] - Pseudomonas; E=0.002 swissprot:P33698; EXOP_RHIME SUCCINOGLYCAN BIOSYNTHESIS TRANSPORT; E=0.010 pir:S37031; probable succinoglycan transport protein exoP -; E=0.021 COG: PA2235; COG3206 Uncharacterized protein involved in; E=2e-04.
       0.572
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.528
wecG
PMID: 8905231 best DB hits: BLAST: pir:S74482; UDP-N-acetyl-D-mannosaminuronic acid transferase rffM-1; E=6e-44 pir:C82265; UDP-N-acetyl-D-mannosamine transferase VC0927 [imported]; E=2e-20 gb:AAC78668.1; (AF094575) putative N-acetyl-mannosamine; E=1e-15 COG: slr1118; COG1922 Teichoic acid biosynthesis proteins; E=5e-45; Belongs to the glycosyltransferase 26 family.
       0.448
RB12602
Similar to chitooligosaccharide deacetylase; Best DB hits: BLAST: pir:T35588; probable secreted protein - Streptomyces coelicolor; E=0.24 ddbj:BAB05636.1; (AP001513) chitooligosaccharide deacetylase; E=0.63 PFAM: PF01522; Polysaccharide deacetylase; E=0.00027.
       0.448
RB12604
Similar to hexosyltransferase; Best DB hits: BLAST: gb:AAF14309.1; (U45308) SqdX [Synechococcus sp. PCC 7942]; E=0.009 pir:T34839; probable hexosyltransferase (EC 2.4.1.-) SC2G5.06; E=0.031 pir:T35514; probable glycosyl transferase - Streptomyces coelicolor; E=0.072.
       0.448
RB12606
Cps2E; PMID: 99184998 best DB hits: BLAST: gb:AAD24451.1; AF118389_8 (AF118389) Cps2E [Streptococcus suis]; E=4e-34 pir:S75572; glucosyltransferase - Synechocystis sp. (strain PCC; E=1e-33 pir:JC5726; phosphate-prenyl glycosyl-1-phosphate transferase (EC; E=9e-33 COG: slr0820; COG2148 Sugar transferases involved in lipopolysaccharide; E=9e-35 PFAM: PF02397; Bacterial sugar transferase; E=3.6e-52.
       0.448
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.