STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaEDNA polymerase III alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1145 aa)    
Predicted Functional Partners:
RB2871
Hypothetical protein; PMID: 12004073.
  
 
 0.899
dnaN
DNA polymerase III, beta chain; PMID: 2540413 best DB hits: BLAST: swissprot:P13455; DP3B_PSEPU DNA POLYMERASE III, BETA CHAIN; E=1e-31 pir:C81713; DNA polymerase III, beta chain TC0347 [imported] -; E=1e-29 pir:E71559; probable DNA pol III (beta chain) - Chlamydia; E=1e-29 COG: CT075; COG0592 DNA polymerase III beta subunit; E=1e-30 PFAM: PF00712; DNA polymerase III beta subun; E=7.1e-16 PF02767; DNA polymerase III beta subun; E=2.4e-12 PF02768; DNA polymerase III beta subun; E=1e-10.
    
 
 0.892
ssb
Single-strand binding protein; PMID: 6270666 PMID: 6384214 best DB hits: BLAST: swissprot:O83101; SSB_TREPA SINGLE-STRAND BINDING PROTEIN (SSB); E=7e-23 embl:CAA76674.1; (Y17166) single strand DNA binding protein; E=1e-19 pir:B81310; single-strand DNA binding protein Cj1071 [imported] -; E=1e-19 COG: TP0062; COG0629 Single-stranded DNA-binding protein; E=7e-24 PFAM: PF00436; Single-strand binding protein family; E=1.7e-48.
   
 
 0.892
dnaQ
Best DB hits: BLAST: swissprot:P13267; DPO3_BACSU DNA POLYMERASE III, ALPHA CHAIN; E=8e-09 pir:JH0232; DNA-directed DNA polymerase (EC 2.7.7.7) III alpha chain; E=8e-09 gb:AAA22666.1; (M22996) polymerase III [Bacillus subtilis]; E=9e-09 COG: BS_polC; COG2176 DNA polymerase III alpha subunit, the Gram-positive; E=8e-10 Rv2191_1; COG0847 DNA polymerase III epsilon subunit (3'-5'; E=2e-09 TM0576; COG2176 DNA polymerase III alpha subunit, the Gram-positive; E=6e-08 PFAM: PF00929; Exonuclease; E=1.2e-18 PF00533; BRCA1 C Terminus (BRCT) domain; E=2.4e-09.
  
 
 0.889
RB11891
Conserved hypothetical protein; PMID: 10984043 best DB hits: BLAST: pir:G83561; hypothetical protein PA0670 [imported] - Pseudomonas; E=4e-07.
 
  
 0.875
dnaX
DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.871
holB
Best DB hits: BLAST: pir:C75278; DNA polymerase III, taugamma subunit - Deinococcus; E=2e-23 gb:AAB82595.1; (AF025391) DNA polymerase III holoenzyme tau; E=4e-22 pir:A70460; DNA polymerase III gamma subunit - Aquifex aeolicus; E=9e-21 COG: DR2410; COG2812 DNA polymerase III, gamma/tau subunits; E=2e-24 NMB0769; COG0470 ATPase involved in DNA replication; E=1e-19 Cj1157; COG2812 DNA polymerase III, gamma/tau subunits; E=4e-18 PFAM: PF00448; SRP54-type protein, GTPase domain; E=0.64 PF00004; ATPase family associated with vario; E=0.0033.
 
 
 0.862
RB11894
Conserved hypothetical protein; PMID: 10984043 best DB hits: BLAST: pir:H83561; hypothetical protein PA0671 [imported] - Pseudomonas; E=5e-05.
 
  
 0.848
RB12645
Hypothetical protein.
   
 
 0.833
uvrA
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
     
 0.675
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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