STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB12640Probable auxin-responsive-like protein; PMID: 11538549 best DB hits: BLAST: gb:AAD32141.1; AF123503_1 (AF123503) Nt-gh3 deduced protein; E=6e-16 pir:T00515; hypothetical protein T20D16.20 - Arabidopsis thaliana; E=1e-15 ddbj:BAA97524.1; (AB026634) auxin-responsive-like protein; E=1e-14. (559 aa)    
Predicted Functional Partners:
acc
Probable acetyl-CoA carboxylase; PMID: 7592499 best DB hits: BLAST: pir:A57710; acetyl-CoA carboxylase (EC 6.4.1.2) - wheat -----; E=2e-05 prf:2208491A; Ac-CoA carboxylase [Triticum aestivum]; E=2e-05 pir:T09538; acetyl-CoA carboxylase (EC 6.4.1.2) - alfalfa -----; E=3e-05 COG: PA0494; COG0439 Biotin carboxylase; E=2e-04 carB; COG0458 Carbamoylphosphate synthase large subunit (split gene; E=0.001 DR0668; COG0458 Carbamoylphosphate synthase large subunit (split; E=0.002 PFAM: PF02786; Carbamoyl-phosphate synthase L ch; E=0.49.
       0.640
apbA
Probable 2-dehydropantoate 2-reductase; PMID: 9488683 best DB hits: BLAST: swissprot:O50098; APBA_PYRHO PROBABLE 2-DEHYDROPANTOATE; E=5e-09 embl:CAB04765.1; (Z82004) ORF12(1) [Rhodococcus erythropolis]; E=2e-08 pir:T35004; probable oxidoreductase - Streptomyces coelicolor; E=5e-06 COG: PH1390; COG1893 Ketopantoate reductase; E=5e-10 PFAM: PF02558; Ketopantoate reductase PanE/ApbA; E=0.00046.
       0.620
RB12639
Hypothetical protein.
       0.620
RB12643
Hypothetical protein.
       0.572
RB13021
Conserved hypothetical protein-putative receptor protein kinase; PMID: 10731132 best DB hits: BLAST: gb:AAF82144.1; AC034256_8 (AC034256) Contains similarity to F-box; E=2e-07 gb:AAF44956.1; AE003406_161 (AE003416) symbol=BG:DS07108.4; E=1e-04 gb:AAF53475.1; (AE003648) BG:DS07108.4 gene product [Drosophila; E=1e-04.
  
     0.545
rimK-2
PMID: 20437337 best DB hits: BLAST: pir:D82997; ribosomal protein S6 modification protein PA5197; E=3e-76 pir:E82096; ribosomal protein S6 modification protein VC2281; E=2e-74 swissprot:P17116; RIMK_ECOLI RIBOSOMAL PROTEIN S6 MODIFICATION; E=1e-60 COG: PA5197; COG0189 Glutathione synthase/Ribosomal protein S6; E=3e-77 rimK; COG0189 Glutathione synthase/Ribosomal protein S6 modification; E=1e-61 HI1531; COG0189 Glutathione synthase/Ribosomal protein S6; E=2e-50 PFAM: PF02080; Potassium channel; E=3.8e-10.
      0.501
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
     
 0.485
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
     
 0.482
RB7548
Similar to syringomycin biosynthesis enzyme 2; PMID: 98007868 PMID: 99047670 best DB hits: BLAST: gb:AAF01812.1; AF187532_8 (AF187532) SnoK [Streptomyces nogalater]; E=1e-09 gb:AAD50521.1; (U25130) syringomycin biosynthesis enzyme 2; E=1e-09 gb:AAC71711.1; (AF061267) putative alpha-ketoglutarate-dependent; E=1e-07.
  
     0.481
RB1376
Similar to adenylate cyclase regulatory protein; Best DB hits: BLAST: gb:AAF82144.1; AC034256_8 (AC034256) Contains similarity to F-box; E=0.004 ddbj:BAB21785.1; (AB051481) KIAA1694 protein [Homo sapiens]; E=0.061 embl:CAB95328.1; (AL359782) possible putative adenylate cyclase; E=0.096.
  
     0.471
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.