STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glmSPMID: 7476196 best DB hits: BLAST: embl:CAB87226.1; (AL163641) glucosamine-fructose-6-phosphate; E=1e-135 pir:T44486; glutamine--fructose-6-phosphate transaminase; E=1e-133 gb:AAF09884.1; AE001891_3 (AE001891); E=1e-132 COG: DR0302; COG0449 Glucosamine 6-phosphate synthetase, contains; E=1e-133 PFAM: PF00310; Glutamine amidotransferases class-II; E=2.1e-65 PF01380; SIS domain; E=2.2e-39. (594 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase [NADPH] large chain; PMID: 2643092 PMID: 3326786 best DB hits: BLAST: swissprot:Q06434; GLSF_ANTSP FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE; E=0.0 swissprot:P23225; GLSF_MAIZE FERREDOXIN-DEPENDENT GLUTAMATE; E=0.0 swissprot:Q03460; GLSN_MEDSA GLUTAMATE SYNTHASE [NADH], CHLOROPLAST; E=0.0 COG: sll1502_2; COG0069 Glutamate synthetase domain 2; E=0.0 sll1502_1; COG0067 Glutamate synthetase domain 1; E=1e-118 PFAM: PF01645; Conserved region in glutamate; E=5.5e-235 PF01493; Domain of unknown function DU; E=4.2e-95.
   
 0.953
glnII
Glutamine synthetase II; PMID: 2575672 PMID: 1357539 best DB hits: BLAST: swissprot:P04772; GLN2_BRAJA GLUTAMINE SYNTHETASE II; E=1e-103 swissprot:Q02154; GLN2_RHILP GLUTAMINE SYNTHETASE II; E=1e-99 swissprot:P45626; GLN2_RHIME GLUTAMINE SYNTHETASE II; E=9e-97 COG: YPR035w; COG0174 Glutamine synthase; E=5e-83 PFAM: PF00120; Glutamine synthetase; E=3.6e-133.
  
 
 0.942
carB
PMID: 8905231 PMID: 6308632 best DB hits: BLAST: swissprot:P00968; CARB_ECOLI CARBAMOYL-PHOSPHATE SYNTHASE LARGE; E=0.0 pir:S76557; carbamoyl-phosphate synthase (glutamine-hydrolyzing) (EC; E=0.0 gb:AAG10606.1; AC008030_6 (AC008030) carbamoyl phosphate synthetase; E=0.0 COG: AF1274; COG0458 Carbamoylphosphate synthase large subunit (split gene; E=0.0 carB; COG0458 Carbamoylphosphate synthase large subunit (split gene in; E=0.0 BU144; COG0458 Carbamoylphosphate synthase large subunit (split gene; E=0.0 PFAM: PF00289; Carbamoyl-phosphate synthase L; E=2.9e-53 PF02222; ATP-grasp domain; E [...]
   
 0.940
pgi
Glucose-6-phosphate isomerase; PMID: 2549364 best DB hits: BLAST: swissprot:P80860; G6PI_BACSU GLUCOSE-6-PHOSPHATE ISOMERASE (GPI); E=6e-53 ddbj:BAB07062.1; (AP001518) glucose-6-phosphate isomerase; E=4e-52 pir:S15937; glucose-6-phosphate isomerase (EC 5.3.1.9) - Bacillus; E=5e-52 COG: BS_pgi; COG0166 Glucose-6-phosphate isomerase; E=6e-54 PFAM: PF00342; Phosphoglucose isomerase; E=6.8e-31.
  
 
 0.932
purF
Amidophosphoribosyltransferase [precursor]; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
0.927
pfaS
PMID: 10548741 best DB hits: BLAST: gb:AAB89983.1; (AE001017) phosphoribosylformylglycinamidine; E=2e-33 ddbj:BAA20816.1; (AB002359) KIAA0361 [Homo sapiens]; E=2e-26 swissprot:O15067; PUR4_HUMAN PHOSPHORIBOSYLFORMYLGLYCINAMIDINE; E=2e-26 COG: AF1260; COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase,; E=1e-34 NMB1996_2; COG0047 Phosphoribosylformylglycinamidine (FGAM); E=3e-22 HI0752_2; COG0047 Phosphoribosylformylglycinamidine (FGAM) synthase,; E=1e-20.
    
 0.926
gltD
NADH-glutamate synthase small chain; PMID: 2643092 PMID: 3326786 best DB hits: BLAST: ddbj:BAA12742.1; (D85230) small subunit of NADH-dependent; E=1e-163 pir:T49818; probable glutamate synthase (NADPH) [imported] -; E=1e-162 pir:S74625; NADH-glutamate synthase small chain gltD - Synechocystis; E=1e-161 COG: sll1027; COG0493 NADPH-dependent glutamate synthase beta chain and; E=1e-162 PFAM: PF01494; FAD binding domain; E=0.013 PF02254; KTN NAD-binding domain; E=0.036 PF00984; UDP-glucose/GDP-mannose dehydr; E=0.28.
    
 0.921
nagA
N-acetylglucosamine-6-phosphate deacetylase; PMID: 2668691 PMID: 2190615 best DB hits: BLAST: pir:C70845; probable nagA protein - Mycobacterium tuberculosis; E=2e-33 gb:AAK05433.1; AE006366_2 (AE006366); E=1e-32 gb:AAG58267.1; AE005542_9 (AE005542) putative; E=2e-32 COG: Rv3332; COG1820 N-acetylglucosamine-6-phosphate deacetylase; E=2e-34 Ta1060; COG0402 Cytosine deaminase and related metal-dependent; E=0.001 yicP; COG1001 Adenine deaminase; E=0.002 PFAM: PF01979; Adenine deaminase; E=0.071 PF01685; Chlorohydrolase; E=0.002 PF01979; Adenine deaminase; E=8.9e-07.
    
 0.920
nagA-2
N-acetylglucosamine-6-phosphate deacetylase NAGA; PMID: 9634230 best DB hits: BLAST: pir:C70845; probable nagA protein - Mycobacterium tuberculosis; E=8e-23 embl:CAB93044.1; (AL357432) putative deacetylase [Streptomyces; E=2e-19 swissprot:O34450; NAGA_BACSU N-ACETYLGLUCOSAMINE-6-PHOSPHATE; E=5e-18 COG: Rv3332; COG1820 N-acetylglucosamine-6-phosphate deacetylase; E=7e-24 PFAM: PF02612; N-acetylglucosamine-6-phosphate deac; E=5.6e-05.
    
 0.920
carA
Carbamoyl-phosphate synthase, small chain; PMID: 2843375 PMID: 6330744 best DB hits: BLAST: pir:E82083; carbamoyl-phosphate synthase, small chain VC2390; E=1e-99 pir:C70337; carbamoyl phosphate synthetase small subunit - Aquifex; E=3e-98 pir:S76783; hypothetical protein - Synechocystis sp. (strain PCC; E=6e-96 COG: VC2390; COG0505 Carbamoylphosphate synthase small subunit; E=1e-100 PFAM: PF00988; Carbamoyl-phosphate synthase; E=8.7e-82 PF00117; Glutamine amidotransferase cl; E=5.7e-62; Belongs to the CarA family.
    
 0.917
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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