Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
degPSerine proteinase; PMID: 2180903 best DB hits: BLAST: pir:F83550; serine proteinase MucD precursor PA0766 [imported] -; E=1e-50 swissprot:Q44597; DEGP_BRUAB PROBABLE SERINE PROTEASE DO-LIKE; E=9e-47 gb:AAK01318.1; (AF190580) MucD [Pseudomonas syringae pv; E=2e-46 COG: PA0766; COG0265 Trypsin-like serine proteases, typically; E=1e-51 htrA; COG0265 Trypsin-like serine proteases, typically periplasmic,; E=9e-44 aq_1450; COG0265 Trypsin-like serine proteases, typically; E=2e-43 PFAM: PF00089; Trypsin; E=1.8e-14 PF00595; PDZ domain (Also known as DHR or GLG; E=1.4e-10. (509 aa)    
Predicted Functional Partners:
RB12751
Hypothetical protein.
       0.773
groEL
Heat shock protein GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.623
groEL-2
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.623
groEL-3
60 kDa chaperonin 5; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.623
cpsG
Similar to cold shock-like protein cspI; PMID: 8631696 best DB hits: BLAST: swissprot:P77605; CSPI_ECOLI COLD SHOCK-LIKE PROTEIN CSPI; E=0.27 embl:CAA72682.1; (Y11932) cspB [Salmonella typhimurium]; E=0.31 swissprot:Q47130; CSPG_ECOLI COLD SHOCK-LIKE PROTEIN CSPG; E=0.36 PFAM: PF00313; 'Cold-shock' DNA-binding domain; E=6.7e-05.
      
 0.618
htrA
Similar to serine proteinase HtrA; PMID: 9371463 best DB hits: BLAST: pir:D69109; serine proteinase HtrA - Methanobacterium; E=0.014 embl:CAA72164.1; (Y11304) ORF E0 [Rhodobacter capsulatus]; E=0.018 gb:AAF87931.1; AF163841_10 (AF163841) putative serine protease; E=0.041 COG: MTH1813; COG0265 Trypsin-like serine proteases, typically; E=0.001 PFAM: PF00595; PDZ domain (Also known as DHR; E=0.0018.
      
 0.618
htrA-2
Probable serine protease HtrA; PMID: 1645840 best DB hits: BLAST: gb:AAK02818.1; (AE006110) HtrA [Pasteurella multocida]; E=0.003 swissprot:P45129; HTOA_HAEIN PROBABLE PERIPLASMIC SERINE PROTEASE; E=0.010 gb:AAC38202.1; (AF018151) HtrA [Haemophilus influenzae]; E=0.010 COG: HI1259; COG0265 Trypsin-like serine proteases, typically; E=0.001 degQ; COG0265 Trypsin-like serine proteases, typically periplasmic,; E=0.009 PFAM: PF00595; PDZ domain (Also known as DHR o; E=5e-11.
      
 0.618
RB4681
Probable cold shock protein scoF; PMID: 90231432 PMID: 94293754 best DB hits: BLAST: swissprot:P48859; CSPF_STRCO COLD SHOCK PROTEIN SCOF -----; E=8e-10 embl:CAB76978.1; (AL159178) cold-shock protein [Streptomyces; E=2e-09 pir:T34593; cold-shock domain protein - Streptomyces coelicolor; E=1e-08 COG: XF2352; COG1278 Cold shock proteins; E=2e-08 PFAM: PF00313; 'Cold-shock' DNA-binding domain; E=2.2e-19.
      
 0.618
RB7911
Best DB hits: BLAST: pir:T35287; probable secreted proteinase - Streptomyces coelicolor; E=3e-10 gb:AAK02818.1; (AE006110) HtrA [Pasteurella multocida]; E=2e-08 pir:S47170; hypothetical protein 34K - Mycobacterium; E=3e-08 COG: VNG0226G; COG0265 Trypsin-like serine proteases, typically; E=9e-09 htrA; COG0265 Trypsin-like serine proteases, typically periplasmic,; E=2e-08 aq_1450; COG0265 Trypsin-like serine proteases, typically; E=5e-08 PFAM: PF00089; Trypsin; E=0.038.
  
     0.609
degP-5
PMID: 20150255 best DB hits: BLAST: pir:B81728; serine proteinase, HtrADegQ/DegS family TC0210; E=1e-16 swissprot:P18584; DEGP_CHLTR PROBABLE SERINE PROTEASE DO-LIKE; E=2e-16 swissprot:Q9Z6T0; DEGP_CHLPN PROBABLE SERINE PROTEASE DO-LIKE; E=1e-15 COG: CT823; COG0265 Trypsin-like serine proteases, typically periplasmic,; E=2e-17 CPn0979; COG0265 Trypsin-like serine proteases, typically; E=1e-16 RP124; COG0265 Trypsin-like serine proteases, typically periplasmic,; E=3e-08 PFAM: PF00595; PDZ domain (Also known as DHR or GL; E=1.4e-09.
  
   
0.482
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.