node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ffh | ftsY | RB12825 | RB4173 | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.957 |
ffh | rplB | RB12825 | RB7837 | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.926 |
ffh | rplD | RB12825 | RB7834 | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.924 |
ffh | rplO | RB12825 | RB7863 | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.928 |
ffh | rplS | RB12825 | RB12821 | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.963 |
ffh | rpsD | RB12825 | RB1233 | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.922 |
ffh | rpsE | RB12825 | RB7859 | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.945 |
ffh | rpsH-2 | RB12825 | RB7855 | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.920 |
ffh | rspB | RB12825 | RB10638 | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | Ribosomal protein S2; PMID: 6806564 PMID: 6272196 PMID: 7023985 PMID: 10094780 best DB hits: BLAST: pir:F75386; ribosomal protein S2 - Deinococcus radiodurans (strain; E=9e-52 swissprot:Q9WZM1; RS2_THEMA 30S RIBOSOMAL PROTEIN S2 -----; E=2e-51 pdb:1FJF; B Chain B, Structure Of The Thermus Thermophilus 30s; E=2e-50 COG: DR1513; COG0052 Ribosomal protein S2; E=8e-53 PFAM: PF00318; Ribosomal protein S2; E=1.2e-82; Belongs to the universal ribosomal protein uS2 family. | 0.930 |
ffh | secY | RB12825 | RB7866 | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.922 |
ftsY | ffh | RB4173 | RB12825 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | 0.957 |
ftsY | rplB | RB4173 | RB7837 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 0.911 |
ftsY | rplD | RB4173 | RB7834 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.909 |
ftsY | rplO | RB4173 | RB7863 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.922 |
ftsY | rplS | RB4173 | RB12821 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.506 |
ftsY | rpsE | RB4173 | RB7859 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. | 0.486 |
ftsY | secY | RB4173 | RB7866 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.899 |
rplB | ffh | RB7837 | RB12825 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | Signal recognition particle protein; PMID: 6357787 PMID: 1279430 best DB hits: BLAST: pir:F72236; signal recognition particle protein - Thermotoga; E=2e-87 ddbj:BAB06203.1; (AP001515) signal recognition particle [Bacillus; E=2e-85 gb:AAF69242.1; AF173880_5 (AF173880) signal recognition particle; E=3e-84 COG: TM1565; COG0541 Signal recognition particle GTPase; E=2e-88 PFAM: PF02881; SRP54-type protein, helical b; E=8.8e-21 PF02223; Thymidylate kinase; E=0.33 PF00485; Phosphoribulokinase / Uridine; E=0.03. | 0.926 |
rplB | ftsY | RB7837 | RB4173 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.911 |
rplB | rplD | RB7837 | RB7834 | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.997 |