node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
accA | accB | RB8310 | RB8548 | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.995 |
accA | accC | RB8310 | RB8550 | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.993 |
accA | accD | RB8310 | RB12904 | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.999 |
accA | aceF | RB8310 | RB3423 | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | PMID: 6345153 PMID: 6821375 PMID: 2121129 best DB hits: BLAST: pir:C82079; pyruvate dehydrogenase, E2 component, dihydrolipoamide; E=4e-55 pir:H75540; pyruvate dehydrogenase complex, dihydrolipoamide; E=4e-55 gb:AAK02978.1; (AE006128) AceF [Pasteurella multocida]; E=6e-54 COG: VC2413; COG0508 Dihydrolipoamide acyltransferases; E=3e-56 PFAM: PF00364; Biotin-requiring enzyme; E=2.1e-20 PF02817; e3 binding domain; E=8.5e-14 PF00198; 2-oxo acid dehydrogenases acylt; E=8.5e-100. | 0.901 |
accA | acs | RB8310 | RB13264 | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.910 |
accA | fabD | RB8310 | RB314 | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Malonyl CoA-acyl carrier protein transacylase; PMID: 1339356 PMID: 7768883 best DB hits: BLAST: embl:CAB45522.1; (AJ007046) [acyl-carrier protein]; E=9e-58 pir:T00580; probable [acyl-carrier-protein] S-malonyltransferase (EC; E=1e-57 gb:AAG43518.1; AF210698_1 (AF210698) malonyl-CoA:ACP transacylase; E=1e-56 COG: HI0156; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=6e-52 PFAM: PF00698; Acyl transferase domain; E=3.2e-16. | 0.973 |
accA | fabH-2 | RB8310 | RB5678 | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 3-oxoacyl-(acyl-carrier-protein) synthase III; PMID: 1551888 PMID: 10593943 best DB hits: BLAST: pir:C81029; 3-oxoacyl-(acyl-carrier-protein) synthase III NMB1916; E=7e-41 gb:AAK04869.1; AE006310_11 (AE006310); E=1e-39 pir:H82633; beta-ketoacyl-[ACP] synthase III XF1817 [imported] -; E=3e-39 COG: NMB1916; COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; E=7e-42 PFAM: PF02797; Chalcone and stilbene synthas; E=0.31. | 0.960 |
accA | fabH-3 | RB8310 | RB6272 | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 3-oxoacyl-(acyl-carrier protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.960 |
accA | fabZ | RB8310 | RB10466 | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Probable beta-hydroxyacyl-ACP dehydratase; PMID: 7806516 best DB hits: BLAST: gb:AAF98278.1; AF197933_8 (AF197933) beta-hydroxyacyl-ACP; E=1e-05 pir:H81661; (3R)-hydroxymyristol-(acyl carrier protein) dehydratase; E=4e-05 pir:B33171; hypothetical 17K protein (lpxA 5' region) - Escherichia; E=5e-05 COG: fabZ; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier; E=5e-06 PFAM: PF01377; Thioester dehydrase; E=1.3e-15. | 0.781 |
accA | pta | RB8310 | RB9654 | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.906 |
accB | accA | RB8548 | RB8310 | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | AcetylCoA-Carboxylase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.995 |
accB | accC | RB8548 | RB8550 | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.999 |
accB | accD | RB8548 | RB12904 | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. | 0.998 |
accB | aceF | RB8548 | RB3423 | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | PMID: 6345153 PMID: 6821375 PMID: 2121129 best DB hits: BLAST: pir:C82079; pyruvate dehydrogenase, E2 component, dihydrolipoamide; E=4e-55 pir:H75540; pyruvate dehydrogenase complex, dihydrolipoamide; E=4e-55 gb:AAK02978.1; (AE006128) AceF [Pasteurella multocida]; E=6e-54 COG: VC2413; COG0508 Dihydrolipoamide acyltransferases; E=3e-56 PFAM: PF00364; Biotin-requiring enzyme; E=2.1e-20 PF02817; e3 binding domain; E=8.5e-14 PF00198; 2-oxo acid dehydrogenases acylt; E=8.5e-100. | 0.917 |
accB | acs | RB8548 | RB13264 | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.910 |
accB | fabD | RB8548 | RB314 | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Malonyl CoA-acyl carrier protein transacylase; PMID: 1339356 PMID: 7768883 best DB hits: BLAST: embl:CAB45522.1; (AJ007046) [acyl-carrier protein]; E=9e-58 pir:T00580; probable [acyl-carrier-protein] S-malonyltransferase (EC; E=1e-57 gb:AAG43518.1; AF210698_1 (AF210698) malonyl-CoA:ACP transacylase; E=1e-56 COG: HI0156; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=6e-52 PFAM: PF00698; Acyl transferase domain; E=3.2e-16. | 0.975 |
accB | fabH-2 | RB8548 | RB5678 | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 3-oxoacyl-(acyl-carrier-protein) synthase III; PMID: 1551888 PMID: 10593943 best DB hits: BLAST: pir:C81029; 3-oxoacyl-(acyl-carrier-protein) synthase III NMB1916; E=7e-41 gb:AAK04869.1; AE006310_11 (AE006310); E=1e-39 pir:H82633; beta-ketoacyl-[ACP] synthase III XF1817 [imported] -; E=3e-39 COG: NMB1916; COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; E=7e-42 PFAM: PF02797; Chalcone and stilbene synthas; E=0.31. | 0.982 |
accB | fabH-3 | RB8548 | RB6272 | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 3-oxoacyl-(acyl-carrier protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.983 |
accB | fabZ | RB8548 | RB10466 | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Probable beta-hydroxyacyl-ACP dehydratase; PMID: 7806516 best DB hits: BLAST: gb:AAF98278.1; AF197933_8 (AF197933) beta-hydroxyacyl-ACP; E=1e-05 pir:H81661; (3R)-hydroxymyristol-(acyl carrier protein) dehydratase; E=4e-05 pir:B33171; hypothetical 17K protein (lpxA 5' region) - Escherichia; E=5e-05 COG: fabZ; COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier; E=5e-06 PFAM: PF01377; Thioester dehydrase; E=1.3e-15. | 0.880 |
accB | pta | RB8548 | RB9654 | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) accB; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.936 |