STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB12942Hypothetical protein-transmembrane prediction. (500 aa)    
Predicted Functional Partners:
RB12952
Two-component system, regulatory protein; PMID: 7699720 best DB hits: BLAST: pir:D83083; probable two-component response regulator PA4493; E=8e-30 gb:AAF87208.1; AF228577_2 (AF228577) ActR [Rhizobium leguminosarum; E=8e-30 swissprot:Q52913; ACTR_RHIME ACID TOLERANCE REGULATORY PROTEIN; E=1e-29 COG: PA4493; COG0784 CheY-like receiver domains; E=8e-31 TP0519; COG2204 AAA superfamily ATPases with N-terminal receiver; E=3e-12 BH3787; COG0784 CheY-like receiver domains; E=8e-11 PFAM: PF00072; Response regulator receiver doma; E=2.9e-25.
     
 0.700
RB10330
Best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-69 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-56 pir:H83132; probable sensorresponse regulator hybrid PA4112; E=1e-52 COG: PA4982; COG0642 Sensory transduction histidine kinases; E=4e-49 PFAM: PF00512; His Kinase A (phosphoacceptor) d; E=1.3e-22 PF02518; Histidine kinase-, DNA gyrase B-; E=8e-46 PF00072; Response regulator receiver doma; E=6.2e-33.
      
 0.618
ntrC-2
Probable nitrogen regulation protein; PMID: 2882477 best DB hits: BLAST: pir:H70558; hypothetical protein Rv1626 - Mycobacterium tuberculosis; E=3e-16 pir:T35758; probable response regulator - Streptomyces coelicolor; E=4e-15 pir:S52249; response regulator nasT - Azotobacter vinelandii -----; E=1e-12 COG: Rv1626; COG0784 CheY-like receiver domains; E=2e-17 glnG; COG2204 AAA superfamily ATPases with N-terminal receiver; E=3e-06 MTH447_1; COG0784 CheY-like receiver domains; E=2e-04 PFAM: PF00072; Response regulator receiver doma; E=0.0018.
      
 0.618
RB13122
Hypothetical protein.
      
 0.618
RB138
Hypothetical protein.
      
 0.618
RB140
Serine/threonine protein kinase; Best DB hits: BLAST: swissprot:P71584; PKNB_MYCTU PUTATIVE SERINETHREONINE-PROTEIN; E=2e-31 pir:T36717; probable serinethreonine protein kinase - Streptomyces; E=5e-31 swissprot:P54744; PKNB_MYCLE PUTATIVE SERINETHREONINE-PROTEIN; E=9e-31 COG: Rv0014c_1; COG0515 Serine/threonine protein kinases; E=3e-32 PFAM: PF00069; Protein kinase domain; E=6.9e-49 PF00515; TPR Domain; E=0.72.
      
 0.618
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
      
 0.618
RB5780
Probable response regulator; PMID: 7699720 best DB hits: BLAST: pir:D75276; response regulator - Deinococcus radiodurans (strain R1); E=2e-09 embl:CAB62661.1; (AL133422) hypothetical protein SCM1.03c; E=4e-08 swissprot:Q55169; RCP1_SYNY3 RESPONSE REGULATOR RCP1 -----; E=4e-08 COG: DR2420; COG0784 CheY-like receiver domains; E=2e-10 VC0790; COG2197 Response regulators consisting of a CheY-like; E=0.002 citB; COG2197 Response regulators consisting of a CheY-like receiver; E=0.004 PFAM: PF00072; Response regulator receiver doma; E=2.1e-10.
      
 0.618
RB12945
Conserved hypothetical protein-putative protein chain release factor B; PMID: 2215213 best DB hits: BLAST: swissprot:P45388; YAEJ_PSEPU HYPOTHETICAL 15.2 KD PROTEIN IN PCAJ; E=3e-16 embl:CAA63804.1; (X93605) hypothetical protein YAEJ [Zymomonas; E=7e-15 pir:A83538; conserved hypothetical protein PA0868 [imported] -; E=4e-12 COG: PA0868; COG1186 Protein chain release factor B; E=4e-13 sll1110; COG0216 Protein chain release factor A; E=0.010 PFAM: PF00472; Peptidyl-tRNA hydrolase domain; E=2.2e-09.
  
    0.546
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.