STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB12945Conserved hypothetical protein-putative protein chain release factor B; PMID: 2215213 best DB hits: BLAST: swissprot:P45388; YAEJ_PSEPU HYPOTHETICAL 15.2 KD PROTEIN IN PCAJ; E=3e-16 embl:CAA63804.1; (X93605) hypothetical protein YAEJ [Zymomonas; E=7e-15 pir:A83538; conserved hypothetical protein PA0868 [imported] -; E=4e-12 COG: PA0868; COG1186 Protein chain release factor B; E=4e-13 sll1110; COG0216 Protein chain release factor A; E=0.010 PFAM: PF00472; Peptidyl-tRNA hydrolase domain; E=2.2e-09. (142 aa)    
Predicted Functional Partners:
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
  0.928
rpsP
Probable 30S ribosomal protein S16; PMID: 6357787 PMID: 8730873 best DB hits: BLAST: pir:T05282; ribosomal protein S16, organellar - Arabidopsis; E=3e-15 gb:AAK05667.1; AE006387_10 (AE006387) 30S ribosomal protein S16; E=7e-14 ddbj:BAA97024.1; (AB024035) 30S ribosomal protein S16; E=1e-13 COG: BH2483; COG0228 Ribosomal protein S16; E=2e-14 PFAM: PF00886; Ribosomal protein S16; E=1.8e-20; Belongs to the bacterial ribosomal protein bS16 family.
  
 
 0.887
rpmA
50S ribosomal protein L27; PMID: 10617197 PMID: 1225626 best DB hits: BLAST: gb:AAC64229.1; (AC005167) 50S ribosomal protein L27 [Arabidopsis; E=4e-19 swissprot:O87885; RL27_LAWIN 50S RIBOSOMAL PROTEIN L27 -----; E=1e-18 pir:T49957; ribosomal protein L27-like - Arabidopsis thaliana; E=2e-18 COG: VC0436; COG0211 Ribosomal protein L27; E=2e-18 PFAM: PF01016; Ribosomal L27 protein; E=6.4e-44; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.876
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
 
 0.851
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
 
 0.851
rplT
Probable 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
 0.839
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.831
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
   
 
 0.827
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 0.825
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
 0.824
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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