STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB12946Hypothetical protein; Best DB hits: PFAM: PF02151; UvrB/uvrC motif; E=0.0011. (244 aa)    
Predicted Functional Partners:
yacI
Creatine kinase-putative ATP:guanido kinase (YacI); Catalyzes the specific phosphorylation of arginine residues in proteins; Belongs to the ATP:guanido phosphotransferase family.
  
  
 0.850
RB12949
Histidine protein kinase; PMID: 8757734 best DB hits: BLAST: gb:AAB38420.1; (L39938) histidine protein kinase [Sinorhizobium; E=2e-16 pir:E83083; probable two-component sensor PA4494 [imported] -; E=3e-16 gb:AAA93222.1; (U22925) RegB [Rhodobacter sphaeroides]; E=2e-12 COG: PA4494; COG0642 Sensory transduction histidine kinases; E=2e-17 PFAM: PF00512; His Kinase A (phosphoacceptor; E=0.011 PF02518; Histidine kinase-, DNA gyrase; E=1.2e-28.
       0.732
clpC
Negative regulator of genetic competence ClpC/MecB; PMID: 8016066 best DB hits: BLAST: pir:T36384; probable ATP-binding proteinase - Streptomyces; E=0.0 swissprot:P37571; CLPC_BACSU NEGATIVE REGULATOR OF GENETIC; E=0.0 ddbj:BAB03822.1; (AP001507) class III stress response-related; E=0.0 COG: BS_clpC; COG0542 ATPases with chaperone activity, ATP-binding domain; E=0.0 PFAM: PF02861; Clp amino terminal domain; E=7.5e-19 PF00004; ATPase family associated with; E=1.6e-12 PF02151; UvrB/uvrC motif; E=2.3e-09; Belongs to the ClpA/ClpB family.
  
  
 0.591
clpB
ClpB protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity). Belongs to the ClpA/ClpB family.
  
  
 0.591
RB12945
Conserved hypothetical protein-putative protein chain release factor B; PMID: 2215213 best DB hits: BLAST: swissprot:P45388; YAEJ_PSEPU HYPOTHETICAL 15.2 KD PROTEIN IN PCAJ; E=3e-16 embl:CAA63804.1; (X93605) hypothetical protein YAEJ [Zymomonas; E=7e-15 pir:A83538; conserved hypothetical protein PA0868 [imported] -; E=4e-12 COG: PA0868; COG1186 Protein chain release factor B; E=4e-13 sll1110; COG0216 Protein chain release factor A; E=0.010 PFAM: PF00472; Peptidyl-tRNA hydrolase domain; E=2.2e-09.
       0.529
RB12952
Two-component system, regulatory protein; PMID: 7699720 best DB hits: BLAST: pir:D83083; probable two-component response regulator PA4493; E=8e-30 gb:AAF87208.1; AF228577_2 (AF228577) ActR [Rhizobium leguminosarum; E=8e-30 swissprot:Q52913; ACTR_RHIME ACID TOLERANCE REGULATORY PROTEIN; E=1e-29 COG: PA4493; COG0784 CheY-like receiver domains; E=8e-31 TP0519; COG2204 AAA superfamily ATPases with N-terminal receiver; E=3e-12 BH3787; COG0784 CheY-like receiver domains; E=8e-11 PFAM: PF00072; Response regulator receiver doma; E=2.9e-25.
       0.439
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.