STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB13026Probable monooxygenase; PMID: 1444267 best DB hits: BLAST: pir:T37167; probable oxidoreductase - Streptomyces coelicolor; E=4e-08 gb:AAD25066.1; AF121000_13 (AF121000) oxidoreductase protein; E=0.001 pir:D83122; probable FAD-dependent monooxygenase PA4190 [imported] -; E=0.004 COG: PA4190; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related; E=4e-04 PFAM: PF01360; Monooxygenase; E=0.33. (197 aa)    
Predicted Functional Partners:
RB13025
Probable monooxygenase; PMID: 1444267 best DB hits: BLAST: pir:D83229; probable FAD-dependent monooxygenase PA3328 [imported] -; E=1e-07 pir:H70986; probable hyroxylase - Mycobacterium tuberculosis (strain; E=2e-07 pir:T35323; probable hydroxylase - Streptomyces coelicolor -----; E=1e-06 COG: PA3328; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related; E=1e-08 BS_yetM; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and; E=2e-04 PA2587; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related; E=5e-04 PFAM: PF01360; Monooxygenase; E=2.8e-12.
     0.989
cypX
Probable cytochrome P450 T9E850; PMID: 20411542 best DB hits: BLAST: pir:T06288; probable cytochrome P450 T9E8.50 - Arabidopsis thaliana; E=5e-14 ddbj:BAA31438.1; (AB010393) ALK6 [Yarrowia lipolytica]; E=3e-13 pir:C81286; probable cytochrome P450 Cj1411c [imported] -; E=5e-13 COG: Cj1411c; COG2124 Cytochrome P450; E=4e-14 PFAM: PF00067; Cytochrome P450; E=1e-20.
 
 
 0.633
RB13028
Hypothetical protein-transmembrane prediction; Best DB hits: BLAST: ddbj:BAA92043.1; (AK002026) unnamed protein product [Homo; E=0.87 ddbj:BAB13962.1; (AK022105) unnamed protein product [Homo; E=0.87 ref:XP_012653.1; hypothetical protein FLJ11164 [Homo sapiens]; E=0.87.
       0.572
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
 
 
 0.570
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
  
 
 0.511
RB12112
Best DB hits: BLAST: pir:T50995; related to cytoskeleton assembly control protein SLA1; E=6e-07 pir:T37781; probable cytoskeleton assembly control protein - fission; E=5e-05 embl:CAA84826.1; (Z35768) ORF YBL007c [Saccharomyces cerevisiae]; E=0.18.
  
     0.478
ribD
PMID: 9068650 best DB hits: BLAST: pir:T50546; riboflavin bifunctional biosynthesis protein ribG; E=2e-56 swissprot:P50853; RIBD_ACTPL RIBOFLAVIN BIOSYNTHESIS PROTEIN RIBD; E=2e-56 ddbj:BAB05273.1; (AP001512) riboflavin specific; E=9e-52 COG: ribD_1; COG0117 Pyrimidine deaminase; E=1e-28 BH1554_2; COG1985 Pyrimidine reductase, riboflavin biosynthesis; E=6e-21 CPn0871_1; COG0117 Pyrimidine deaminase; E=1e-20 PFAM: PF00383; Cytidine and deoxycytidylate de; E=1.5e-31 PF01872; RibD C-terminal domain; E=4e-33.
   
 
 0.451
betA
GMC oxidoreductase; PMID: 92177421 best DB hits: BLAST: pir:C75453; GMC oxidoreductase - Deinococcus radiodurans (strain R1); E=9e-35 swissprot:Q00593; ALKJ_PSEOL ALCOHOL DEHYDROGENASE [ACCEPTOR]; E=3e-28 embl:CAB51051.1; (AJ233397) alcohol dehydrogenase [Pseudomonas; E=3e-25 COG: DR0965; COG2303 Choline dehydrogenase and related flavoproteins; E=9e-36 PFAM: PF01494; FAD binding domain; E=0.085 PF00732; GMC oxidoreductases; E=2.3e-09 PF01583; Adenylylsulfate kinase; E=0.85.
  
  
 0.447
pcxB
PMID: 8407791 best DB hits: BLAST: pir:E83626; protocatechuate 3,4-dioxygenase, beta subunit PA0153; E=1e-14 pir:T35018; protocatechuate 3,4-dioxygenase beta chain -; E=1e-14 gb:AAF65837.1; AF253466_3 (AF253466) protocatechuate; E=3e-14 PFAM: PF00652; QXW lectin repeat; E=0.28 PF00775; Dioxygenase; E=3.6e-18.
 
   
 0.412
RB386
Saframycin Mx1 synthetase B; PMID: 8936303 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-112 pir:T34918; polyketide synthase - Streptomyces coelicolor -----; E=1e-102 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=1e-101 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-102 Rv1529; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-83 Ta1189; COG0156 7-keto-8-aminopelargonate synthetase and related; E=6e-62 PFAM: PF00501; AMP-binding enzyme; E=2.2e-08 PF00550; Phosphopantetheine attac [...]
  
 
 0.409
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.