Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
apaHProbable diadenosine tetraphosphatase; PMID: 3031429 best DB hits: BLAST: pir:C83259; hypothetical protein PA3087 [imported] - Pseudomonas; E=1e-54 ddbj:BAB06564.1; (AP001516) diadenosine tetraphosphatase; E=8e-10 embl:CAA11911.1; (AJ224354) protein serine-threonine phosphatase,; E=6e-08 COG: PA3087; COG0639 Diadenosine tetraphosphatase and related; E=1e-55. (309 aa)    
Predicted Functional Partners:
ubiG
PMID: 1479344 best DB hits: BLAST: pir:C83249; 3-demethylubiquinone-9 3-methyltransferase PA3171; E=0.004 swissprot:P08442; YAT1_SYNP6 ATP SYNTHASE SUBUNITS REGION ORF 1; E=0.055 pir:S76629; hypothetical protein - Synechocystis sp. (strain PCC; E=0.19 COG: PA3171; COG2227; E=3e-04.
 
 
   0.780
nudH
Similar to (di)nucleoside polyphosphate hydrolase; PMID: 11479323 best DB hits: BLAST: swissprot:Q46930; NUDH_ECOLI PROBABLE (DI)NUCLEOSIDE POLYPHOSPHATE; E=0.16.
       0.773
RB10074
Conserved hypothetical protein-putative SAM-dependent methyltransferase; Best DB hits: BLAST: pir:G69742; hypothetical protein ybaJ - Bacillus subtilis -----; E=7e-13 pir:E83313; conserved hypothetical protein PA2650 [imported] -; E=9e-12 pir:S76919; hypothetical protein - Synechocystis sp. (strain PCC; E=6e-04 COG: BS_ybaJ; COG0500 SAM-dependent methyltransferases; E=7e-14 XF2471; COG2227; E=0.004.
   
   0.748
RB1858
Conserved hypothetical protein; PMID: 12093901 best DB hits: BLAST: pir:H82553; 3-demethylubiquinone-9 3-methyltransferase XF2471; E=0.027 pir:T30158; hypothetical protein C37A2.6 - Caenorhabditis elegans; E=0.030 embl:CAA89660.1; (Z49629) ORF YJR129c [Saccharomyces cerevisiae]; E=0.76 COG: XF2471; COG2227; E=0.003.
   
   0.748
tehB
Probable tellurite resistance protein TehB; PMID: 10339832 PMID: 2060788 best DB hits: BLAST: ddbj:BAB05779.1; (AP001514) BH2060~unknown [Bacillus halodurans]; E=5e-05 gb:AAD31610.1; (AF079807) tellurite resistance protein TehB; E=1e-04 swissprot:P45134; TEHB_HAEIN TELLURITE RESISTANCE PROTEIN TEHB; E=2e-04 COG: HI1275; COG0500 SAM-dependent methyltransferases; E=2e-05 VNG1117C; COG2520 Predicted methyltransferase; E=0.001 NMB1617; COG0500 SAM-dependent methyltransferases; E=0.002.
   
   0.748
gufA
Probable gufA protein homolog-putative divalent heavy-metal cations transporter; Best DB hits: BLAST: pir:C70127; gufA protein homolog - Lyme disease spirochete -----; E=2e-05 pir:T29905; hypothetical protein F59A3.4 - Caenorhabditis elegans; E=0.002 pir:E75052; gufA protein homolog PAB1443 - Pyrococcus abyssi (strain; E=0.027 COG: BB0219; COG0428 Predicted divalent heavy-metal cations transporter; E=2e-06.
      
 0.618
uspA
Conserved hypothetical protein-putative universal stress protein; PMID: 8688087 best DB hits: BLAST: swissprot:Q57951; Y531_METJA HYPOTHETICAL PROTEIN MJ0531 -----; E=4e-10 ddbj:BAB03102.1; (AP002040) gene_id:MEC18.3~unknown protein; E=2e-08 pir:A69220; conserved hypothetical protein MTH898 - Methanobacterium; E=2e-08 COG: MJ0531; COG0589 Universal stress protein UspA and related; E=4e-11 PFAM: PF00582; Universal stress protein family; E=3.9e-11.
      
 0.618
uspA-3
Conserved hypothetical protein-putative universal stress protein; PMID: 8905231 best DB hits: BLAST: swissprot:P74148; YD88_SYNY3 HYPOTHETICAL 17.3 KD PROTEIN SLL1388; E=2e-05 gb:AAG20091.1; (AE005088) Vng1898c [Halobacterium sp. NRC-1]; E=5e-05 swissprot:Q57951; Y531_METJA HYPOTHETICAL PROTEIN MJ0531 -----; E=7e-04 COG: sll1388; COG0589 Universal stress protein UspA and related; E=2e-06 PFAM: PF00582; Universal stress protein family; E=0.04.
      
 0.618
RB13109
Hypothetical protein.
       0.567
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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