Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB13147PMID: 7910580 best DB hits: BLAST: embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=7e-62 gb:AAB03341.1; (U62317) arylsulfatase A [Homo sapiens]; E=7e-62 gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=3e-61 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=5e-31 PFAM: PF00884; Sulfatase; E=1.2e-107. (478 aa)    
Predicted Functional Partners:
RB4561
Beta-hexosaminidase; PMID: 8969205 PMID: 10220172 best DB hits: BLAST: pir:B82755; beta-hexosaminidase precursor XF0847 [imported] -; E=2e-35 swissprot:P96155; HEX1_VIBFU BETA-HEXOSAMINIDASE; E=4e-26 pir:A82301; beta-N-acetylhexosaminidase VC0613 [imported] - Vibrio; E=2e-25 PFAM: PF02838; Glycosyl hydrolase family 20,; E=0.00019 PF00728; Glycosyl hydrolase family 20,; E=5.3e-07.
    
  0.901
RB13148
Iduronate-sulfatase or arylsulfatase A; Best DB hits: BLAST: embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=1e-60 gb:AAB03341.1; (U62317) arylsulfatase A [Homo sapiens]; E=1e-60 pdb:1E2S; P Chain P, Crystal Structure Of An Arylsulfatase A; E=1e-59 COG: ydeN; COG3119 Arylsulfatase A and related enzymes; E=8e-31 PFAM: PF00814; Glycoprotease family; E=0.2 PF00884; Sulfatase; E=1.6e-93 PF00884; Sulfatase; E=4.5e-52.
 
    
0.800
RB13150
Sialic-acid O-acetylesterase; PMID: 8662838 best DB hits: BLAST: gb:AAB07813.1; (U40408) sialic-acid O-acetylesterase [Mus; E=2e-19 embl:CAA67214.1; (X98625) sialic acid-specific 9-O-acetylesterase; E=7e-19 gb:AAD55976.1; (AF156856) cytosolic sialic acid; E=9e-15.
       0.773
RB13154
Probable lipase/esterase; PMID: 10567266 best DB hits: BLAST: pir:B75555; probable lipaseesterase - Deinococcus radiodurans; E=8e-04 pir:T51415; Carboxylesterase-like protein - Arabidopsis thaliana; E=0.071 gb:AAF32448.1; (AC021640) hypothetical protein [Arabidopsis; E=0.17 PFAM: PF01738; Dienelactone hydrolase family; E=3.9e-07.
       0.773
RB13155
PMID: 8020961 best DB hits: BLAST: ddbj:BAA04535.1; (D17629) N-acetylgalactosamine 6-sulfate; E=2e-49 gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=4e-49 pir:S07089; arylsulfatase (EC 3.1.6.1) - sea urchin (Lytechinus; E=5e-42 COG: ydeN; COG3119 Arylsulfatase A and related enzymes; E=7e-33 PFAM: PF00884; Sulfatase; E=6.3e-54.
 
    
0.679
RB3353
Sialidase [Precursor]; PMID: 1400240 PMID: 8591030 best DB hits: BLAST: swissprot:Q02834; NANH_MICVI SIALIDASE PRECURSOR (NEURAMINIDASE); E=3e-40 pdb:1EUR; Sialidase ----- pdb: 1EUS Sialidase Complexed; E=3e-40 pdb:1EUU; Sialidase Or Neuraminidase, Large 68kd Form -----; E=3e-40 PFAM: PF02012; BNR repeat; E=0.1.
     
  0.650
nanH
Neuraminidase precursor; PMID: 8093075 best DB hits: BLAST: ddbj:BAA05853.1; (D28493) neuraminidase precursor [Bacteroides; E=4e-90 pir:JC2500; exo-alpha-sialidase (EC 3.2.1.18) precursor -; E=8e-89 swissprot:P31206; NANH_BACFR SIALIDASE (NEURAMINIDASE) -----; E=2e-68 PFAM: PF02012; BNR repeat; E=0.038.
     
  0.650
RB6738
Hypothetical protein.
 
      0.624
glnII
Glutamine synthetase II; PMID: 2575672 PMID: 1357539 best DB hits: BLAST: swissprot:P04772; GLN2_BRAJA GLUTAMINE SYNTHETASE II; E=1e-103 swissprot:Q02154; GLN2_RHILP GLUTAMINE SYNTHETASE II; E=1e-99 swissprot:P45626; GLN2_RHIME GLUTAMINE SYNTHETASE II; E=9e-97 COG: YPR035w; COG0174 Glutamine synthase; E=5e-83 PFAM: PF00120; Glutamine synthetase; E=3.6e-133.
      
 0.618
pepT
Aminopeptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
      
 0.618
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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