Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RB13155PMID: 8020961 best DB hits: BLAST: ddbj:BAA04535.1; (D17629) N-acetylgalactosamine 6-sulfate; E=2e-49 gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=4e-49 pir:S07089; arylsulfatase (EC 3.1.6.1) - sea urchin (Lytechinus; E=5e-42 COG: ydeN; COG3119 Arylsulfatase A and related enzymes; E=7e-33 PFAM: PF00884; Sulfatase; E=6.3e-54. (500 aa)    
Predicted Functional Partners:
RB3353
Sialidase [Precursor]; PMID: 1400240 PMID: 8591030 best DB hits: BLAST: swissprot:Q02834; NANH_MICVI SIALIDASE PRECURSOR (NEURAMINIDASE); E=3e-40 pdb:1EUR; Sialidase ----- pdb: 1EUS Sialidase Complexed; E=3e-40 pdb:1EUU; Sialidase Or Neuraminidase, Large 68kd Form -----; E=3e-40 PFAM: PF02012; BNR repeat; E=0.1.
     
  0.900
nanH
Neuraminidase precursor; PMID: 8093075 best DB hits: BLAST: ddbj:BAA05853.1; (D28493) neuraminidase precursor [Bacteroides; E=4e-90 pir:JC2500; exo-alpha-sialidase (EC 3.2.1.18) precursor -; E=8e-89 swissprot:P31206; NANH_BACFR SIALIDASE (NEURAMINIDASE) -----; E=2e-68 PFAM: PF02012; BNR repeat; E=0.038.
     
  0.900
RB13156
Probable lipase/esterase; PMID: 10567266 best DB hits: BLAST: pir:H70731; probable esterase - Mycobacterium tuberculosis (strain; E=4e-10 embl:CAA04934.1; (AJ001695) esterase [Thermotoga maritima]; E=2e-09 pir:F72287; esterase - Thermotoga maritima (strain MSB8) -----; E=2e-09 COG: Rv2284; COG0657 Acetyl esterase; E=4e-11 slr0825; COG1506 Dipeptidyl aminopeptidases/acylaminoacyl-peptidases; E=8e-08 DR0821_2; COG0657 Acetyl esterase; E=6e-07 PFAM: PF00036; EF hand; E=0.59.
       0.773
RB13157
Mucin-desulfating sulfatase; PMID: 9710560 PMID: 10809675 best DB hits: BLAST: gb:AAF72520.1; AF248951_1 (AF248951) mucin-desulfating sulfatase; E=6e-35 gb:AAF55296.1; (AE003712) Sulf1 gene product [Drosophila; E=2e-28 pir:T16584; hypothetical protein K09C4.8 - Caenorhabditis elegans; E=3e-24 COG: yidJ; COG3119 Arylsulfatase A and related enzymes; E=1e-24 BS_yqgS; COG1368 Phosphoglycerol transferase and related proteins,; E=0.007 PFAM: PF02455; Hexon-associated protein (IIIa); E=0.25 PF00884; Sulfatase; E=8e-47.
 
    
0.750
RB13148
Iduronate-sulfatase or arylsulfatase A; Best DB hits: BLAST: embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=1e-60 gb:AAB03341.1; (U62317) arylsulfatase A [Homo sapiens]; E=1e-60 pdb:1E2S; P Chain P, Crystal Structure Of An Arylsulfatase A; E=1e-59 COG: ydeN; COG3119 Arylsulfatase A and related enzymes; E=8e-31 PFAM: PF00814; Glycoprotease family; E=0.2 PF00884; Sulfatase; E=1.6e-93 PF00884; Sulfatase; E=4.5e-52.
 
    
0.693
RB13147
PMID: 7910580 best DB hits: BLAST: embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=7e-62 gb:AAB03341.1; (U62317) arylsulfatase A [Homo sapiens]; E=7e-62 gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=3e-61 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=5e-31 PFAM: PF00884; Sulfatase; E=1.2e-107.
 
    
0.679
RB13162
Conserved hypothetical protein-putative eukaryotic thiol (cysteine) proteases; PMID: 8843436 best DB hits: BLAST: embl:CAB56147.1; (AL117669) hypothetical protein [Streptomyces; E=7e-12 embl:CAB55704.1; (AL117387) putative secreted protein; E=4e-09 embl:CAB94651.1; (AL359215) putative polysaccharide lyase; E=1e-04.
       0.661
RB13150
Sialic-acid O-acetylesterase; PMID: 8662838 best DB hits: BLAST: gb:AAB07813.1; (U40408) sialic-acid O-acetylesterase [Mus; E=2e-19 embl:CAA67214.1; (X98625) sialic acid-specific 9-O-acetylesterase; E=7e-19 gb:AAD55976.1; (AF156856) cytosolic sialic acid; E=9e-15.
       0.590
RB13154
Probable lipase/esterase; PMID: 10567266 best DB hits: BLAST: pir:B75555; probable lipaseesterase - Deinococcus radiodurans; E=8e-04 pir:T51415; Carboxylesterase-like protein - Arabidopsis thaliana; E=0.071 gb:AAF32448.1; (AC021640) hypothetical protein [Arabidopsis; E=0.17 PFAM: PF01738; Dienelactone hydrolase family; E=3.9e-07.
       0.590
xylR-2
Xylose operon regulatory protein; PMID: 8041620 best DB hits: BLAST: swissprot:P45043; XYLR_HAEIN XYLOSE OPERON REGULATORY PROTEIN; E=5e-38 swissprot:P37390; XYLR_ECOLI XYLOSE OPERON REGULATORY PROTEIN; E=8e-38 ddbj:BAB03212.1; (AB046360) putative xylose operon regulatory; E=2e-28 COG: HI1106_1; COG1609 Transcriptional regulators; E=1e-23 xylR_2; COG2207 AraC-type DNA-binding domain-containing proteins; E=4e-12 BH3692; COG1609 Transcriptional regulators; E=2e-05 PFAM: PF00165; Bacterial regulatory helix-turn-hel; E=3.1e-16.
       0.495
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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