STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xylR-2Xylose operon regulatory protein; PMID: 8041620 best DB hits: BLAST: swissprot:P45043; XYLR_HAEIN XYLOSE OPERON REGULATORY PROTEIN; E=5e-38 swissprot:P37390; XYLR_ECOLI XYLOSE OPERON REGULATORY PROTEIN; E=8e-38 ddbj:BAB03212.1; (AB046360) putative xylose operon regulatory; E=2e-28 COG: HI1106_1; COG1609 Transcriptional regulators; E=1e-23 xylR_2; COG2207 AraC-type DNA-binding domain-containing proteins; E=4e-12 BH3692; COG1609 Transcriptional regulators; E=2e-05 PFAM: PF00165; Bacterial regulatory helix-turn-hel; E=3.1e-16. (403 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase [NADPH] large chain; PMID: 2643092 PMID: 3326786 best DB hits: BLAST: swissprot:Q06434; GLSF_ANTSP FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE; E=0.0 swissprot:P23225; GLSF_MAIZE FERREDOXIN-DEPENDENT GLUTAMATE; E=0.0 swissprot:Q03460; GLSN_MEDSA GLUTAMATE SYNTHASE [NADH], CHLOROPLAST; E=0.0 COG: sll1502_2; COG0069 Glutamate synthetase domain 2; E=0.0 sll1502_1; COG0067 Glutamate synthetase domain 1; E=1e-118 PFAM: PF01645; Conserved region in glutamate; E=5.5e-235 PF01493; Domain of unknown function DU; E=4.2e-95.
    
 
 0.911
RB3549
Probable lactose operon transcription activator; PMID: 9573174 best DB hits: BLAST: ddbj:BAB05677.1; (AP001513) BH1958~unknown conserved protein; E=1e-07 swissprot:O33813; LACR_STAXY LACTOSE OPERON TRANSCRIPTION; E=4e-07 ddbj:BAB07561.1; (AP001520) two-component response regulator; E=6e-07 COG: BH1958; COG2207 AraC-type DNA-binding domain-containing proteins; E=1e-08 BH0394; COG2169 Adenosine deaminase; E=2e-06 PA2337; COG2207 AraC-type DNA-binding domain-containing proteins; E=3e-06 PFAM: PF00165; Bacterial regulatory helix-turn-heli; E=3.7e-20.
 
 
 0.813
RB9879
Best DB hits: BLAST: pir:C83489; probable transcription regulator PA1261 [imported] -; E=6e-26 pir:H83309; probable transcriptional regulator PA2696 [imported] -; E=8e-14 ddbj:BAB04708.1; (AP001510) transcriptional regulator (AraCXylS; E=1e-11 COG: PA1261; COG2207 AraC-type DNA-binding domain-containing proteins; E=5e-27 PFAM: PF00989; PAS domain; E=0.18 PF00165; Bacterial regulatory helix-turn-heli; E=7.6e-24.
  
 
 0.733
RB10655
Best DB hits: BLAST: pir:G83352; transcription regulator MtlR PA2337 [imported] -; E=1e-09 pir:S52856; AraC-like protein - Azorhizobium caulinodans -----; E=1e-08 gb:AAF43900.1; (U20115) adpA-like protein [Mycobacterium; E=2e-08 COG: PA2337; COG2207 AraC-type DNA-binding domain-containing proteins; E=1e-10 BS_adaA; COG2169 Adenosine deaminase; E=1e-05 araC; COG2207 AraC-type DNA-binding domain-containing proteins; E=1e-05 PFAM: PF00165; Bacterial regulatory helix-turn-heli; E=1.4e-21.
  
 
 0.708
rhaR
PMID: 3316663 best DB hits: BLAST: swissprot:P09378; RHAR_ECOLI L-RHAMNOSE OPERON TRANSCRIPTIONAL; E=1e-25 gb:AAG59100.1; AE005622_2 (AE005622) positive regulator for rhaRS; E=2e-25 gb:AAG59099.1; AE005622_1 (AE005622) positive regulator for rhaBAD; E=2e-20 COG: rhaR; COG2207 AraC-type DNA-binding domain-containing proteins; E=1e-26 PFAM: PF00165; Bacterial regulatory helix-turn-heli; E=2.7e-30.
  
 
 0.689
araC-3
Best DB hits: BLAST: pir:T35901; probable araC family transcription regulator -; E=1e-17 swissprot:Q03320; ARAL_STRAT PUTATIVE ARAC-LIKE TRANSCRIPTION; E=2e-16 swissprot:P35319; ARAL_STRLI PUTATIVE ARAC-LIKE TRANSCRIPTION; E=2e-15 COG: ykgD; COG2207 AraC-type DNA-binding domain-containing proteins; E=2e-12 VCA1018_1; COG2169 Adenosine deaminase; E=3e-05 VCA1074; COG2207 AraC-type DNA-binding domain-containing proteins; E=3e-05 PFAM: PF00440; Bacterial regulatory proteins, tetR; E=0.37 PF00165; Bacterial regulatory helix-turn-heli; E=3.5e-25 PF01047; MarR family; E=0.25.
  
 
 0.650
RB13168
Hypothetical protein-signal peptide prediction.
       0.628
RB3345
Activator protein MtlR; PMID: 9666063 best DB hits: BLAST: pir:G83352; transcription regulator MtlR PA2337 [imported] -; E=3e-30 gb:AAC34292.1; (AF047527) activator protein [Pseudomonas; E=2e-26 pir:G82221; transcription regulator AraCXylS family VC1260; E=2e-16 COG: PA2337; COG2207 AraC-type DNA-binding domain-containing proteins; E=3e-31 PFAM: PF00165; Bacterial regulatory helix-turn-heli; E=3.5e-21.
  
 
 0.615
RB3692
Probable Xyls/AraC-type transcriptional activator; PMID: 10543838 best DB hits: BLAST: pir:E83158; probable transcription regulator PA3898 [imported] -; E=1e-17 ddbj:BAA86295.1; (AB006902) XylsAraC-type transcriptional; E=2e-17 pir:S77548; lumQ protein - Synechocystis sp. (strain PCC 6803); E=4e-16 COG: PA3898; COG2207 AraC-type DNA-binding domain-containing proteins; E=1e-18 PFAM: PF00165; Bacterial regulatory helix-turn-heli; E=8e-24.
  
 
 0.606
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
  
 
 0.579
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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