STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ddlAProbable D-alanine-D-alanine ligase; PMID: 8125347 best DB hits: BLAST: swissprot:P55650; Y4SG_RHISN HYPOTHETICAL 37.0 KD PROTEIN Y4SG; E=1e-17 swissprot:O66806; DDL_AQUAE D-ALANINE--D-ALANINE LIGASE; E=1e-10 swissprot:P44405; DDL_HAEIN D-ALANINE--D-ALANINE LIGASE; E=3e-10 COG: aq_521; COG1181 D-alanine-D-alanine ligase and related ATP-grasp; E=1e-11 PFAM: PF01820; D-ala D-ala ligase; E=7.8e-06. (341 aa)    
Predicted Functional Partners:
RB2662
Hypothetical protein-signal peptide and transmembrane prediction.
  
  
 0.900
serB
Probable phosphoserine phosphatase; PMID: 2997734 best DB hits: BLAST: pir:C83025; probable phosphoserine phosphatase PA4960 [imported] -; E=1e-108 pir:E70860; probable serB2 protein - Mycobacterium tuberculosis; E=1e-60 pir:T36772; probable phosphoserine phosphatase - Streptomyces; E=1e-57 COG: PA4960_2; COG0560 Phosphoserine phosphatase; E=5e-70 PA4960_1; COG2716 ACT domain-containing protein; E=3e-31 jhp0597; COG0560 Phosphoserine phosphatase; E=6e-26 PFAM: PF01842; ACT domain; E=0.052 PF00702; haloacid dehalogenase-like hy; E=3.6e-26.
  
    0.736
RB13273
Hypothetical protein.
       0.626
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.616
capB
Capsule biosynthesis protein CapB; PMID: 2536679 best DB hits: BLAST: swissprot:P19580; CAPB_BACAN CAPB PROTEIN ----- pir: A30091; E=7e-53 gb:AAF13663.1; AF188935_61 (AF188935) pXO2-58 [Bacillus anthracis]; E=7e-53 pir:F70069; poly-gamma-glutamic synthesis pgsB protein - Bacillus; E=4e-50.
  
  
 0.535
murE
Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase; PMID: 8436954 best DB hits: BLAST: swissprot:Q03523; MURE_BACSU; E=2e-10 ddbj:BAB06290.1; (AP001515); E=4e-09 swissprot:O86491; MURE_STAAU; E=7e-09 COG: BS_murE; COG0769 UDP-N-acetylmuramyl tripeptide synthase; E=2e-11 XF0794; COG0770 UDP-N-acetylmuramyl pentapeptide synthase; E=1e-09 CPn0418; COG0769 UDP-N-acetylmuramyl tripeptide synthase; E=2e-06 PFAM: PF01225; Mur ligase family, catalytic domai; E=0.0033 PF00023; Ank repeat; E=0.019.
  
  
 0.531
RB8580
Probable sigma-54 modulation protein; Best DB hits: BLAST: pir:B53373; hypothetical protein 1 (rpoN 3' region) - Pseudomonas; E=0.004 pir:G82065; probable sigma-54 modulation protein VC2530 [imported]; E=0.005 swissprot:P17160; RP5M_AZOVI PROBABLE SIGMA(54) MODULATION; E=0.007 COG: VC2530; COG1544 Ribosome-associated protein Y (PSrp-1); E=5e-04 PFAM: PF02482; Sigma 54 modulation protein / S; E=0.0074.
  
  
 0.495
lysS
lysyl-tRNA synthetase; Best DB hits: BLAST: swissprot:Q53638; SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA; E=1e-116 swissprot:P37477; SYK_BACSU LYSYL-TRNA SYNTHETASE (LYSINE--TRNA; E=1e-114 swissprot:Q9KGG4; SYK_BACHD LYSYL-TRNA SYNTHETASE (LYSINE--TRNA; E=1e-111 COG: BS_lysS; COG1190 Lysyl-tRNA synthetase class II; E=1e-115 PFAM: PF01336; OB-fold nucleic acid binding dom; E=5.9e-12 PF01409; tRNA synthetases class II (F); E=0.46 PF00152; tRNA synthetases class II (D, K; E=7e-136; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
  
 0.487
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.482
RB8687
Probable beta-lactamase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
     
 0.472
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.