Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RB13306N-carbamoylsarcosine amidase related protein-putative amidase; Best DB hits: BLAST: pir:G82957; hypothetical protein PA5507 [imported] - Pseudomonas; E=8e-34 embl:CAC12181.1; (AL445066) N-carbamoylsarcosine amidase related; E=2e-10 embl:CAC11866.1; (AL445065) conserved hypothetical protein; E=4e-09 COG: PA5507; COG1335 Amidases related to nicotinamidase; E=7e-35 TM0133; COG1535 2,3-Dihydro-2,3 dihydroxybenzoate synthase; E=0.001 aq_994; COG1335 Amidases related to nicotinamidase; E=0.003 PFAM: PF00857; Isochorismatase family; E=3e-15. (247 aa)    
Predicted Functional Partners:
amaB
PMID: 7764340 best DB hits: BLAST: ddbj:BAB04480.1; (AP001509) N-carbamyl-L-amino acid; E=2e-72 gb:AAK02244.1; (AE006050) unknown [Pasteurella multocida]; E=2e-63 swissprot:Q01264; HYUC_PSESN HYDANTOIN UTILIZATION PROTEIN C; E=3e-62 COG: BH0761; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate; E=2e-73 BS_yurH; COG0624 Acetylornithine; E=1e-46 DR1154; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate; E=2e-32 PFAM: PF01546; Peptidase family M20/M25/M40; E=7e-07.
 
    0.891
asnB
Asparagine synthetase; PMID: 10498721 best DB hits: BLAST: gb:AAG02363.1; AF210249_22 (AF210249) asparagine synthetase; E=1e-57 swissprot:P54420; ASNB_BACSU ASPARAGINE SYNTHETASE; E=3e-50 ddbj:BAB05227.1; (AP001512) asparagine synthetase [Bacillus; E=4e-49 COG: BS_asnB; COG0367 Asparagine synthase (glutamine-hydrolyzing); E=2e-51 PFAM: PF00310; Glutamine amidotransferases clas; E=4.1e-15 PF00733; Asparagine synthase; E=1.6e-13.
 
 
   0.797
pyrB
Aspartate carbamoyltransferase, catalytic subunit (pyrB); PMID: 6364131 PMID: 6302686 PMID: 6341995 PMID: 10318893 PMID: 2271529 best DB hits: BLAST: gb:AAB91125.1; (AE001099) aspartate carbamoyltransferase,; E=3e-31 swissprot:P96174; PYRB_VIBS2 ASPARTATE CARBAMOYLTRANSFERASE; E=7e-30 embl:CAC11715.1; (AL445064) probable aspartate; E=2e-29 COG: AF0106; COG0540 Aspartate carbamoyltransferase, catalytic chain; E=2e-32 AF1255; COG0078 Ornithine carbamoyltransferase; E=2e-10 PFAM: PF02729; Aspartate/ornithine carbamoyltransfe; E=3.6e-20 PF00185; Aspartate/ornithine carbamoyltransfe; E=3e-0 [...]
 
     0.776
RB10235
Conserved hypothetical protein-putative hydrolase; Best DB hits: BLAST: pir:G83172; hypothetical protein PA3783 [imported] - Pseudomonas; E=9e-28 pir:G69776; conserved hypothetical protein yddQ - Bacillus subtilis; E=9e-15 ddbj:BAB11178.1; (AB007648) gene_id:MKD15.9~pir C72413~similar to; E=2e-13 COG: PA3783; COG1335 Amidases related to nicotinamidase; E=9e-29 TM0133; COG1535 2,3-Dihydro-2,3 dihydroxybenzoate synthase; E=2e-06 AF2151; COG1335 Amidases related to nicotinamidase; E=2e-06 PFAM: PF00857; Isochorismatase family; E=5.7e-11.
  
     0.755
dur3
Urea transporter or sodium transporter; PMID: 8335627 best DB hits: BLAST: gb:AAB65069.1; (U11582) No definition line found [Saccharomyces; E=6e-16 gb:AAA34582.1; (L19875) Dur3 [Saccharomyces cerevisiae]; E=1e-15 ddbj:BAB09166.1; (AB018113) urea active transporter-like protein; E=3e-11 COG: YHL016c; COG0591 Na+/proline, Na+/panthothenate symporters and; E=6e-17 PFAM: PF00474; Sodium:solute symporter family; E=1.4e-07; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.754
RB13309
Probable c-type cytochrome precursor; PMID: 8063110 PMID: 8195067 PMID: 11372197 best DB hits: BLAST: gb:AAD05531.1; (AF083240) c-type cytochrome precursor [Shewanella; E=5e-07 gb:AAD05534.1; (AF083240) deca-heme c-type cytochrome [Shewanella; E=4e-06 swissprot:Q57142; C554_NITEU CYTOCHROME C-554 PRECURSOR (C554); E=3e-04.
       0.455
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.447
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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