STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB1353Probable Cytochrome ba3-putative manganese transport protein mntH; PMID: 9428682 best DB hits: BLAST: pir:T44945; hypothetical protein 6 [imported] - Natronobacterium; E=7e-14 swissprot:Q9RTP8; MNTH_DEIRA PROBABLE MANGANESE TRANSPORT PROTEIN; E=7e-08 swissprot:Q9RPF4; MNTH_SALTY MANGANESE TRANSPORT PROTEIN MNTH; E=9e-05 COG: DR1709; COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; E=7e-09 PFAM: PF00122; E1-E2 ATPase; E=0.38 PF01566; Natural resistance-associated ma; E=0.00088. (453 aa)    
Predicted Functional Partners:
mntB
Manganese ABC transporter permease protein; PMID: 7743991 best DB hits: BLAST: pir:E69992; conserved hypothetical protein ytgD - Bacillus subtilis; E=3e-41 ddbj:BAB05109.1; (AP001511) BH1390~unknown conserved protein in; E=2e-32 gb:AAD56938.1; AF180520_3 (AF180520) integral membrane protein; E=3e-28 COG: BS_ytgD; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=3e-42 Rv2788; COG1321 Mn-dependent transcriptional regulator; E=3e-10 BH1395; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=5e-10 PFAM: PF00950; ABC 3 transport family; E=1.1e-17 PF02742; Iron dependent repr [...]
  
  
 0.655
mntB-2
PMID: 7743991 best DB hits: BLAST: pir:D69992; ABC transporter (membrane protein) homolog ytgC -; E=8e-45 pir:B71357; probable ABC transporter, permease protein (troC) -; E=5e-22 pir:A72089; integral membrane protein - Chlamydophila pneumoniae; E=4e-21 COG: BS_ytgC; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=8e-46 CPn0347_2; COG1321 Mn-dependent transcriptional regulator; E=2e-07 TM0125; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease; E=3e-07 PFAM: PF00950; ABC 3 transport family; E=1.6e-72 PF02742; Iron dependent repressor, metal; E=1.6e-07.
  
  
 0.655
nagA-2
N-acetylglucosamine-6-phosphate deacetylase NAGA; PMID: 9634230 best DB hits: BLAST: pir:C70845; probable nagA protein - Mycobacterium tuberculosis; E=8e-23 embl:CAB93044.1; (AL357432) putative deacetylase [Streptomyces; E=2e-19 swissprot:O34450; NAGA_BACSU N-ACETYLGLUCOSAMINE-6-PHOSPHATE; E=5e-18 COG: Rv3332; COG1820 N-acetylglucosamine-6-phosphate deacetylase; E=7e-24 PFAM: PF02612; N-acetylglucosamine-6-phosphate deac; E=5.6e-05.
       0.584
NagB
Glucosamine-6-phosphate isomerase NAGB; PMID: 9384377 best DB hits: BLAST: swissprot:O35000; NAGB_BACSU GLUCOSAMINE-6-PHOSPHATE ISOMERASE; E=4e-20 swissprot:O97440; GNP2_GIALA GLUCOSAMINE-6-PHOSPHATE ISOMERASE 2; E=1e-17 gb:AAF03257.1; AF071896_1 (AF071896) glucosamine 6-phosphate; E=2e-17 COG: BS_nagB; COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate; E=4e-21 PFAM: PF01182; Glucosamine-6-phosphate isome; E=4.5e-11.
       0.577
RB11231
Conserved hypothetical protein; Best DB hits: BLAST: gb:AAB90342.1; (AE001041) A. fulgidus predicted coding region; E=0.001 COG: AF0913; COG1416 Uncharacterized ACR; E=1e-04 PFAM: PF01406; tRNA synthetases class I (C); E=0.52.
  
     0.564
RB3967
Probable sodium/proline symporter (proline permease); PMID: 8031825 best DB hits: BLAST: gb:AAG20007.1; (AE005081) pantothenate permease; PanF; E=2e-20 pir:C69115; sodiumproline symporter (proline permease) -; E=3e-11 pir:B69833; metabolite permease homolog yhjB - Bacillus subtilis; E=7e-11 COG: VNG1785G; COG0591 Na+/proline, Na+/panthothenate symporters and; E=2e-21 panF; COG0591 Na+/proline, Na+/panthothenate symporters and related; E=3e-04 NMB0402; COG0591 Na+/proline, Na+/panthothenate symporters and; E=7e-04 PFAM: PF00474; Sodium:solute symporter family; E=0.11; Belongs to the sod [...]
  
     0.401
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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