STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB1411Probable dihydrodipicolinate synthase; PMID: 10761919 best DB hits: BLAST: pir:H81878; probable dihydrodipicolinate synthase (EC 4.2.1.52); E=2e-08 pir:D81141; dihydrodipicolinate synthase NMB0929 [imported] -; E=3e-08 pir:D83488; probable dihydrodipicolinate synthetase PA1254; E=7e-07 COG: NMB0929; COG0329 Dihydrodipicolinate synthetase/N-acetylneuraminate; E=3e-09 PFAM: PF00701; Dihydrodipicolinate synthetase f; E=9.1e-05; Belongs to the DapA family. (342 aa)    
Predicted Functional Partners:
dapA-3
Probable dihydrodipicolinate synthase; PMID: 1463470 best DB hits: BLAST: pir:D81141; dihydrodipicolinate synthase NMB0929 [imported] -; E=3e-09 pir:H81878; probable dihydrodipicolinate synthase (EC 4.2.1.52); E=4e-09 ddbj:BAB05461.1; (AP001513) dihydrodipicolinate synthase; E=1e-07 COG: NMB0929; COG0329 Dihydrodipicolinate synthetase/N-acetylneuraminate; E=3e-10 PFAM: PF01137; RNA 3'-terminal phosphate cyclase; E=0.88 PF00701; Dihydrodipicolinate synthetase famil; E=0.00018; Belongs to the DapA family.
  
  
 
0.902
RB2078
Conserved hypothetical protein-possibly prolineracemase; PMID: 10984043 best DB hits: BLAST: pir:G83487; hypothetical protein PA1268 [imported] - Pseudomonas; E=6e-68 gb:AAF97423.1; AF195522_1 (AF195522) B-cell mitogen precursor; E=2e-22 embl:CAB71312.1; (AJ130879) proline racemase [Clostridium; E=4e-18 COG: VNG0332C; COG0384 Predicted epimerase, PhzC/PhzF homolog; E=0.002.
 
     0.778
RB1887
Probable aldehyde dehydrogenase; Best DB hits: BLAST: pir:S27612; ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.-) -; E=2e-87 pir:S27619; ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.-) -; E=3e-86 pdb:1EYY; A Chain A, Crystal Structure Of The Nadp+ Dependent; E=8e-79 COG: PA2217; COG1012 NAD-dependent aldehyde dehydrogenases; E=9e-80 PFAM: PF00831; Ribosomal L29 protein; E=0.78 PF00171; Aldehyde dehydrogenase family; E=2.9e-07.
  
    0.630
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.622
RB1412
Inositol monophosphatase family protein; PMID: 8626508 best DB hits: BLAST: swissprot:P56160; YHEB_CHLVI HYPOTHETICAL 28.2 KD PROTEIN IN HEMB; E=5e-37 pir:B70646; probable monophosphatase - Mycobacterium tuberculosis; E=4e-34 embl:CAB94593.1; (AL359214) putative monophosphatase; E=2e-33 COG: Rv3137; COG0483 Archaeal fructose-1,6-bisphosphatase and related; E=4e-35 VC2722; COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS); E=2e-13 VC0745; COG0483 Archaeal fructose-1,6-bisphosphatase and related; E=3e-12 PFAM: PF00459; Inositol monophosphatase family; E=6.9e-53.
  
    0.565
gatC
glutamyl-tRNA (Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
  
    0.517
dapA-2
Dihydrodipicolinate synthase; PMID: 8098035 PMID: 7853400 PMID: 8081752 best DB hits: BLAST: swissprot:Q07607; MOSA_RHIME MOSA PROTEIN ----- pir: B53308; E=2e-29 embl:CAC24079.1; (AL512981) ORF-c25_010 [Sulfolobus solfataricus]; E=7e-29 pir:S56523; dihydrodipicolinate synthase homolog yjhH - Escherichia; E=1e-28 COG: yjhH; COG0329 Dihydrodipicolinate synthetase/N-acetylneuraminate; E=1e-29 PFAM: PF00701; Dihydrodipicolinate synthetase famil; E=2.2e-57.
  
     0.467
RB8941
Ketoglutarate semialdehyde dehydrogenase; PMID: 96118391 PMID: 20363527 best DB hits: BLAST: pir:S27619; ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.-) -; E=2e-65 pir:S27612; ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.-) -; E=6e-61 pdb:1EYY; A Chain A, Crystal Structure Of The Nadp+ Dependent; E=5e-54 COG: PA2217; COG1012 NAD-dependent aldehyde dehydrogenases; E=4e-54 PFAM: PF00171; Aldehyde dehydrogenase family; E=3.5e-08.
  
    0.461
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
  
 0.445
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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