STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB1412Inositol monophosphatase family protein; PMID: 8626508 best DB hits: BLAST: swissprot:P56160; YHEB_CHLVI HYPOTHETICAL 28.2 KD PROTEIN IN HEMB; E=5e-37 pir:B70646; probable monophosphatase - Mycobacterium tuberculosis; E=4e-34 embl:CAB94593.1; (AL359214) putative monophosphatase; E=2e-33 COG: Rv3137; COG0483 Archaeal fructose-1,6-bisphosphatase and related; E=4e-35 VC2722; COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS); E=2e-13 VC0745; COG0483 Archaeal fructose-1,6-bisphosphatase and related; E=3e-12 PFAM: PF00459; Inositol monophosphatase family; E=6.9e-53. (308 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 
 0.918
hisC
Histidinol-phosphate aminotransferase; PMID: 1400209 best DB hits: BLAST: swissprot:P73807; HIS8_SYNY3 HISTIDINOL-PHOSPHATE AMINOTRANSFERASE; E=1e-56 swissprot:P45358; HIS8_ACEXY HISTIDINOL-PHOSPHATE AMINOTRANSFERASE; E=2e-52 gb:AAK00147.1; AF222753_2 (AF222753) putative aminotransferase; E=2e-43 COG: sll1958; COG0079 Histidinol-phosphate aminotransferase/Tyrosine; E=1e-57 PFAM: PF00155; Aminotransferase class-I; E=5.1e-06 PF00222; Aminotransferase class-II; E=1.3e-17; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase s [...]
  
 
 0.916
RB1411
Probable dihydrodipicolinate synthase; PMID: 10761919 best DB hits: BLAST: pir:H81878; probable dihydrodipicolinate synthase (EC 4.2.1.52); E=2e-08 pir:D81141; dihydrodipicolinate synthase NMB0929 [imported] -; E=3e-08 pir:D83488; probable dihydrodipicolinate synthetase PA1254; E=7e-07 COG: NMB0929; COG0329 Dihydrodipicolinate synthetase/N-acetylneuraminate; E=3e-09 PFAM: PF00701; Dihydrodipicolinate synthetase f; E=9.1e-05; Belongs to the DapA family.
  
    0.565
RB1413
Hypothetical protein.
       0.526
nusA
N utilization substance protein A; Participates in both transcription termination and antitermination.
   
   0.452
sun
Sun/nucleolar protein family protein-putative tRNA and rRNA cytosine-C5-methylase; Best DB hits: BLAST: pir:A82193; Sunnucleolar protein family protein VC1502 [imported] -; E=3e-23 gb:AAG56825.1; AE005406_4 (AE005406) putative nucleolar proteins; E=2e-21 pir:C64945; probable rRNA methylase yebU - Escherichia coli -----; E=5e-21 COG: yebU_1; COG0144 tRNA and rRNA cytosine-C5-methylases; E=5e-22 PFAM: PF01189; NOL1/NOP2/sun family; E=1.1e-24; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
  
  
 0.429
rpoZ
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.413
nusB
Probable N utilization substance protein B homolog; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
   
 
 0.409
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.407
rpoC
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.407
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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