STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpeRibulose-phosphate 3-epimerase; PMID: 10625676 best DB hits: BLAST: pir:G82052; ribulose-phosphate 3-epimerase VC2625 [imported] -; E=1e-42 gb:AAK03703.1; (AE006199) Dod [Pasteurella multocida]; E=1e-40 gb:AAF01048.1; AF189365_1 (AF189365) D-ribulose-5-phosphate; E=3e-40 COG: VC2625; COG0036 Pentose-5-phosphate-3-epimerase; E=1e-43 PFAM: PF00834; Ribulose-phosphate 3 epimerase; E=1.8e-85. (235 aa)    
Predicted Functional Partners:
tkt
Transketolase; PMID: 7859749 best DB hits: BLAST: swissprot:P45694; TKT_BACSU TRANSKETOLASE ----- pir: G69723; E=1e-171 ddbj:BAB06071.1; (AP001515) transketolase [Bacillus halodurans]; E=1e-169 swissprot:Q43848; TKTC_SOLTU TRANSKETOLASE, CHLOROPLAST PRECURSOR; E=1e-164 COG: BS_tkt; COG0021 Transketolase; E=1e-172 PFAM: PF00456; Transketolase, thiamine dipho; E=1.1e-160 PF02779; Transketolase, central domain; E=1.2e-77 PF02780; Transketolase, C-terminal dom; E=1.1e-49; Belongs to the transketolase family.
 0.990
xylB
Xylulose kinase; PMID: 9495747 best DB hits: BLAST: gb:AAC46146.1; (AF001974) xylulose kinase; XylB; E=1e-108 swissprot:P39211; XYLB_BACSU XYLULOSE KINASE (XYLULOKINASE); E=4e-79 ddbj:BAB06475.1; (AP001516) xylose kinase [Bacillus halodurans]; E=5e-76 COG: BS_xylB; COG1070 Sugar (pentulose and hexulose) kinases; E=4e-80 PAB2406; COG0554 Glycerol kinase; E=2e-31 APE0017; COG1070 Sugar (pentulose and hexulose) kinases; E=1e-27 PFAM: PF00370; FGGY family of carbohydrate kinas; E=6e-96 PF02782; FGGY family of carbohydrate kinas; E=7.6e-63.
 
  
 0.965
6pgD
6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 0.947
araB
L-ribulokinase; PMID: 9084180 best DB hits: BLAST: swissprot:P94524; ARAB_BACSU L-RIBULOKINASE ----- pir: D69587; E=3e-97 gb:AAD45717.1; AF160811_5 (AF160811) L-ribulokinase [Bacillus; E=3e-96 embl:CAA61586.1; (X89408) L-ribulokinase [Bacillus subtilis]; E=6e-96 COG: BS_araB; COG1069 Ribulose kinase; E=3e-98 TM0284; COG1070 Sugar (pentulose and hexulose) kinases; E=1e-14 TM1430; COG0554 Glycerol kinase; E=7e-06 PFAM: PF00370; FGGY family of carbohydrate kinas; E=7.8e-06 PF01869; BadF/BadG/BcrA/BcrD ATPase family; E=0.0012 PF02782; FGGY family of carbohydrate kinas; E=1.4e-16; Belongs t [...]
 
   
 0.942
rpiB
PMID: 8576032 best DB hits: BLAST: ddbj:BAB07486.1; (AP001519) ribose 5-phosphate epimerase (pentose; E=3e-30 pir:H70397; ribose 5-phosphate isomerase B - Aquifex aeolicus; E=9e-29 embl:CAA07515.1; (AJ007446) hypothetical protein [Thermotoga; E=7e-27 COG: BH3767; COG0698 Ribose 5-phosphate isomerase RpiB; E=2e-31 PFAM: PF02502; Ribose/Galactose Isomerase; E=1.1e-35.
 
 
 0.936
rpiB-2
PMID: 8576032 best DB hits: BLAST: ddbj:BAB07486.1; (AP001519) ribose 5-phosphate epimerase (pentose; E=2e-28 swissprot:P37351; RPIB_ECOLI RIBOSE 5-PHOSPHATE ISOMERASE B; E=3e-27 pir:H70397; ribose 5-phosphate isomerase B - Aquifex aeolicus; E=3e-27 COG: BH3767; COG0698 Ribose 5-phosphate isomerase RpiB; E=2e-29 PFAM: PF02502; Ribose/Galactose Isomerase; E=5e-43.
 
 
 0.936
RB5319
Best DB hits: BLAST: gb:AAB90381.1; (AE001045) D-arabino 3-hexulose 6-phosphate; E=1e-33 pir:B71209; probable D-arabino 3-hexulose 6-phosphate formaldehyde; E=8e-33 pir:C75022; d-arabino 3-hexulose 6-phosphate formaldehyde lyase; E=7e-28 COG: AF0861_1; COG0269 3-hexulose-6-phosphate synthase and related; E=1e-33 sgaH; COG0269 3-hexulose-6-phosphate synthase and related proteins; E=4e-10 VCA0242; COG0269 3-hexulose-6-phosphate synthase and related; E=3e-09 PFAM: PF00834; Ribulose-phosphate 3 epimerase; E=0.56 PF02581; Thiamine monophosphate synthas; E=0.01.
    
 0.901
kdgK
2-keto-3-deoxygluconate kinase; PMID: 8157608 best DB hits: BLAST: pir:G72422; 2-keto-3-deoxygluconate kinase - Thermotoga maritima; E=1e-15 embl:CAB61818.1; (AL133236) putative sugar kinase [Streptomyces; E=2e-08 pir:D83362; probable 2-ketogluconate kinase PA2261 [imported] -; E=2e-06 COG: TM0067; COG0524 Sugar kinases, ribokinase family; E=1e-16 PFAM: PF00294; pfkB family carbohydrate kinase; E=3.8e-10.
  
 0.863
rsgA
Conserved hypothetical protein-putative GTPase; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
 
    0.848
pgaM
Probable phosphoglycerate mutase; PMID: 9537320 best DB hits: BLAST: pir:A70471; phosphoglycerate mutase 1 - Aquifex aeolicus -----; E=4e-12 pir:A75439; probable phosphoglycerate mutase - Deinococcus; E=2e-11 pir:G72260; phosphoglycerate mutase - Thermotoga maritima (strain; E=2e-11 COG: aq_1990; COG0406 Phosphoglycerate mutase/fructose-2,6-bisphosphatase; E=4e-13 Rv2228c_2; COG0406 Phosphoglycerate; E=3e-05 slr1748; COG0406 Phosphoglycerate mutase/fructose-2,6-bisphosphatase; E=4e-05 PFAM: PF00300; Phosphoglycerate mutase family; E=0.0029.
  
  
 0.827
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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