STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB161Response regulator; PMID: 7699720 best DB hits: BLAST: pir:G82211; response regulator VC1348 [imported] - Vibrio cholerae; E=4e-59 embl:CAB89843.1; (AJ251547) response regulator [Xanthomonas; E=2e-56 pir:S75132; sensory transduction system regulatory protein slr2100 -; E=1e-55 COG: VC1348_2; COG2206 HD-GYP domain; E=1e-42 PFAM: PF00072; Response regulator receiver doma; E=1.1e-29 PF01966; HD domain; E=0.003. (418 aa)    
Predicted Functional Partners:
RB12571
GGDEF family protein; PMID: 10567266 best DB hits: BLAST: pir:E75266; GGDEF family protein - Deinococcus radiodurans (strain; E=2e-27 gb:AAA87378.1; (L42554) pleD gene product [Caulobacter; E=2e-25 gb:AAD28578.1; AF121341_2 (AF121341) putative response regulator; E=3e-25 COG: DR2498; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=2e-28 TM1594; COG2199 Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); E=7e-21 yddV_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=9e-21 PFAM: PF00897; Orbivirus inner capsid protein VP7; E=0.89 PF00498; FHA domain; E=1.3e-19 PF [...]
  
 0.934
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.823
RB3373
PMID: 9098081 best DB hits: BLAST: pir:T28655; receptor-like histidine kinase BpdS - Rhodococcus sp; E=1e-60 pir:T30898; receptor-like histidine kinase - Rhodococcus erythropolis; E=1e-60 pir:S75136; sensory transduction histidine kinase slr2104 -; E=9e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-41 PFAM: PF00069; Protein kinase domain; E=8.1e-08 PF00515; TPR Domain; E=0.026 PF00512; His Kinase A (phosphoacceptor); E=1.4e-21.
 
 
 0.813
RB13175
PMID: 2201868 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-67 pir:S75142; sensory transduction histidine kinase slr1759 -; E=2e-55 embl:CAA65047.1; (X95731) putative sensor kinase [Synechocystis; E=3e-55 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-50 PFAM: PF00989; PAS domain; E=0.011 PF00785; PAC motif; E=0.075 PF00989; PAS domain; E=0.46.
 
 0.766
RB10308
Probable response regulatory protein; PMID: 9823893 PMID: 10984043 best DB hits: BLAST: pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=2e-21 pir:A82428; sensory boxGGDEF family protein VCA0697 [imported] -; E=6e-21 pir:E83183; probable two-component response regulator PA3702; E=1e-20 COG: VCA0697_3; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=6e-22 PFAM: PF00072; Response regulator receiver doma; E=5.4e-17 PF00990; GGDEF domain; E=7.2e-44.
  
 0.763
RB1357
Conserved hypothetical protein; PMID: 10984043 best DB hits: BLAST: pir:H70302; conserved hypothetical protein aq_035 - Aquifex aeolicus; E=2e-26 pir:A71678; probable response regulatory protein RP237 - Rickettsia; E=5e-21 pir:G82209; GGDEF family protein VC1353 [imported] - Vibrio cholerae; E=8e-21 COG: aq_035_2; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=2e-27 PFAM: PF00990; GGDEF domain; E=2.6e-46.
 
  
 0.760
RB12326
Sensory histidine protein kinase; PMID: 11406410 best DB hits: BLAST: gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=2e-45 pir:F83153; probable two-component sensor PA3946 [imported] -; E=3e-36 pir:E83265; probable two-component sensor PA3044 [imported] -; E=2e-35 COG: PA3044; COG0642 Sensory transduction histidine kinases; E=2e-36 PFAM: PF01590; GAF domain; E=3.2e-20 PF00989; PAS domain; E=1.2e-07 PF00512; His Kinase A (phosphoacceptor) d; E=4.8e-16.
 
 0.722
RB10488
PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42.
 
0.698
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
0.694
RB5465
PMID: 7699720 best DB hits: BLAST: pir:D83041; probable two-component response regulator PA4843; E=4e-20 pir:F82960; hypothetical protein PA5487 [imported] - Pseudomonas; E=5e-18 pir:A82428; sensory boxGGDEF family protein VCA0697 [imported] -; E=4e-17 COG: PA5487; COG2199 Diguanylate cyclase/phosphodiesterase domain 1; E=5e-19 PFAM: PF00072; Response regulator receiver doma; E=3.1e-13 PF00990; GGDEF domain; E=3.1e-35.
  
 0.693
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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