STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB1621Conserved hypothetical protein; PMID: 11756688 best DB hits: BLAST: pir:A82542; conserved hypothetical protein XF2574 [imported] -; E=0.028 pir:T29446; hypothetical protein - Streptomyces coelicolor -----; E=0.57 COG: XF2574; COG0671 Membrane-associated phospholipid phosphatase; E=0.003 PFAM: PF01569; PAP2 superfamily; E=0.00063. (350 aa)    
Predicted Functional Partners:
cypX
Probable cytochrome P450 T9E850; PMID: 20411542 best DB hits: BLAST: pir:T06288; probable cytochrome P450 T9E8.50 - Arabidopsis thaliana; E=5e-14 ddbj:BAA31438.1; (AB010393) ALK6 [Yarrowia lipolytica]; E=3e-13 pir:C81286; probable cytochrome P450 Cj1411c [imported] -; E=5e-13 COG: Cj1411c; COG2124 Cytochrome P450; E=4e-14 PFAM: PF00067; Cytochrome P450; E=1e-20.
   
 0.660
RB386
Saframycin Mx1 synthetase B; PMID: 8936303 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-112 pir:T34918; polyketide synthase - Streptomyces coelicolor -----; E=1e-102 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=1e-101 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-102 Rv1529; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-83 Ta1189; COG0156 7-keto-8-aminopelargonate synthetase and related; E=6e-62 PFAM: PF00501; AMP-binding enzyme; E=2.2e-08 PF00550; Phosphopantetheine attac [...]
   
 0.601
rplF
50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.592
RB1624
Hypothetical protein.
       0.541
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
   
 
 0.479
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
   
 
 0.476
aas
Acyl-[ACP]--phospholipid O-acyltransferase; PMID: 8300626 best DB hits: BLAST: pir:A81368; probable 2-acylglycerophosphoethanolamine acyltransferase; E=2e-89 swissprot:P31119; AAS_ECOLI AAS BIFUNCTIONAL PROTEIN [INCLUDES:; E=5e-59 gb:AAG57948.1; AE005512_7 (AE005512); E=6e-59 COG: Cj0938c_3; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=6e-66 aas_2; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=6e-50 VNG1339C; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=2e-28 PFAM: PF01553; Acyltransferase; E=7.6e-22 PF00501; AMP-binding enzyme; E=2.4e-07.
   
 0.408
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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