STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ugdHUDP-glucose 6-dehydrogenase; PMID: 8938413 best DB hits: BLAST: pir:T51527; UDP-glucose dehydrogenase-like protein - Arabidopsis; E=1e-155 ddbj:BAB02581.1; (AP001309) UDP-glucose dehydrogenase; E=1e-151 swissprot:Q96558; UGDH_SOYBN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC; E=1e-150 COG: aq_024; COG1004 Predicted UDP-glucose 6-dehydrogenase; E=2e-61 VC0918; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; E=1e-27 PA3540; COG1004 Predicted UDP-glucose 6-dehydrogenase; E=8e-26 PFAM: PF00984; UDP-glucose/GDP-mannose dehydro; E=2.6e-180; Belongs to the UDP-glucose/GDP-mannose dehydrogena [...] (477 aa)    
Predicted Functional Partners:
RB3733
dTDP-glucose 4-6-dehydratase; PMID: 9174344 best DB hits: BLAST: pir:G82785; dTDP-glucose 4-6-dehydratase XF0611 [imported] - Xylella; E=1e-116 pir:S75550; dTDP-glucose 4-6-dehydratase - Synechocystis sp. (strain; E=1e-114 pir:T00419; dTDP-glucose 4-6-dehydratase homolog T30B22.4 -; E=1e-101 COG: XF0611; COG0451 Nucleoside-diphosphate-sugar epimerases; E=1e-117 MTH1789; COG1088 dTDP-D-glucose 4,6-dehydratase; E=2e-21 PA3554_2; COG0451 Nucleoside-diphosphate-sugar epimerases; E=3e-21 PFAM: PF01073; 3-beta hydroxysteroid dehydrogenase; E=0.0012 PF00106; short chain dehydrogenase; E=0.006 [...]
 0.996
hasC
PMID: 7499387 best DB hits: BLAST: pir:A75096; UTP--glucose-1-phosphate uridylyltransferase (EC; E=3e-20 gb:AAD32398.1; AAD32398 (AF065404) pXO1-94 [Bacillus anthracis]; E=4e-19 swissprot:Q54713; HASC_STRPY UTP--GLUCOSE-1-PHOSPHATE; E=2e-17 COG: PAB0771; COG1210 UDP-glucose pyrophosphorylase; E=3e-21 PAB0784; COG1209 dTDP-glucose pyrophosphorylase; E=3e-04 PFAM: PF00483; Nucleotidyl transferase; E=0.014.
  
 0.971
galE
Udp-glucose 4-epimerase; PMID: 9679194 best DB hits: BLAST: pir:D75143; udp-glucose 4-epimerase (gale-1) PAB2145 - Pyrococcus; E=8e-42 pir:A71183; probable UDP-glucose 4-epimerase - Pyrococcus horikoshii; E=3e-40 pir:T51252; dTDPglucose 4,6-dehydratase (EC 4.2.1.46) [imported] -; E=4e-37 COG: PAB2145; COG0451 Nucleoside-diphosphate-sugar epimerases; E=8e-43 BH3364; COG1088 dTDP-D-glucose 4,6-dehydratase; E=2e-26 TM0630; COG0451 Nucleoside-diphosphate-sugar epimerases; E=5e-26 PFAM: PF00056; lactate/malate dehydrogenase, NAD b; E=0.011 PF01370; NAD dependent epimerase/dehydratase; E=7.1e-43.
 0.970
galE-3
UDP-glucose 4-epimerase; PMID: 11058132 best DB hits: BLAST: swissprot:Q9KDV3; GALE_BACHD UDP-GLUCOSE 4-EPIMERASE; E=9e-99 pir:A69184; UDP-glucose 4-epimerase - Methanobacterium; E=3e-98 gb:AAK06077.1; AE006428_1 (AE006428) UDP-glucose 4-epimerase (EC; E=2e-93 COG: BH1108; COG1087 UDP-glucose 4-epimerase; E=1e-100 TM0509; COG0451 Nucleoside-diphosphate-sugar epimerases; E=9e-41 MPN257; COG1087 UDP-glucose 4-epimerase; E=6e-38 PFAM: PF02716; Isoflavone reductase; E=0.13 PF02254; KTN NAD-binding domain; E=0.22 PF00984; UDP-glucose/GDP-mannose dehyd; E=0.0085.
  
 
 0.938
RB2500
UDP-glucose 4-epimerase; PMID: 11337471 best DB hits: BLAST: gb:AAK04309.1; AE006259_3 (AE006259) UDP-glucose 4-epimerase; E=1e-23 swissprot:Q57664; GALE_METJA PUTATIVE UDP-GLUCOSE 4-EPIMERASE; E=1e-23 gb:AAG18701.1; (AE004975) UDP-glucose 4-epimerase; GalE2; E=3e-23 COG: MJ0211; COG0451 Nucleoside-diphosphate-sugar epimerases; E=1e-24 MTH631; COG1087 UDP-glucose 4-epimerase; E=5e-20 PH0378; COG0451 Nucleoside-diphosphate-sugar epimerases; E=1e-19 PFAM: PF01073; 3-beta hydroxysteroid dehydrogenase; E=0.64 PF00106; short chain dehydrogenase; E=0.0027 PF01370; NAD dependent epimerase/deh [...]
 
 0.935
rfbB
dTDP-glucose-4,6-dehydratase; PMID: 8022265 best DB hits: BLAST: gb:AAG35060.1; AF314183_2 (AF314183) dTDP-glucose-4,6-dehydratase; E=1e-110 gb:AAF33465.1; (AF233324) 89% identity with E. coli; E=1e-107 swissprot:P55294; RFBB_NEIMB DTDP-GLUCOSE 4,6-DEHYDRATASE -----; E=1e-106 COG: NMB0063; COG1088 dTDP-D-glucose 4,6-dehydratase; E=1e-107 PFAM: PF01073; 3-beta hydroxysteroid dehydro; E=0.53 PF00106; short chain dehydrogenase; E=0.073 PF01370; NAD dependent epimerase/dehyd; E=6e-141; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
  
 0.827
rfbE
CDP-tyvelose epimerase; PMID: 96125720 PMID: 97158136 PMID: 2793833 best DB hits: BLAST: gb:AAB48319.1; (U29691) CDP-tyvelose epimerase [Yersinia; E=2e-29 swissprot:P14169; RFBE_SALTI CDP-TYVELOSE-2-EPIMERASE -----; E=3e-27 pir:B33604; rfbE protein - Salmonella sp; E=7e-26 COG: HI0873; COG1088 dTDP-D-glucose 4,6-dehydratase; E=5e-19 BH3649; COG0451 Nucleoside-diphosphate-sugar epimerases; E=1e-14 PH0414; COG1088 dTDP-D-glucose 4,6-dehydratase; E=1e-14 PFAM: PF01370; NAD dependent epimerase/dehydratase; E=0.0012.
  
  
 0.827
galT
Galactose-1-phosphate uridylyltransferase; PMID: 10360571 best DB hits: BLAST: pir:A72322; hypothetical protein TM0896 - Thermotoga maritima; E=3e-47 ddbj:BAB09478.1; (AB012246) galactose-1-phosphate uridyl; E=1e-36 gb:AAF64398.1; AF148553_2 (AF148553) adenylylsulfate:phosphate; E=1e-35 COG: TM0896; COG1085 Galactose-1-phosphate uridylyltransferase; E=3e-48.
    
 0.810
RB1785
Hypothetical protein.
       0.773
RB10428
Probable polysaccharide biosynthesis related protein; Best DB hits: BLAST: gb:AAC44056.1; (U51197) unknown [Sphingomonas sp. S88]; E=1e-12 pir:H75097; polysaccharide biosynthesis related protein PAB0783 -; E=4e-05 COG: PAB0783; COG2244 Membrane protein involved in the export of; E=3e-06 PFAM: PF01943; Polysaccharide biosynthesis pro; E=0.02.
  
  
 0.735
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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