STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
NqrASodium-translocating NADH:ubiquinone oxidoreductase subunit nqrA; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (471 aa)    
Predicted Functional Partners:
nqrB
Sodium-translocating NADH dehydrogenase (ubiquinone) subunit nqrB; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
 0.999
nqrC
Sodium-translocating NADH dehydrogenase (ubiquinone) subunit nqrC; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
 
 0.999
nqrD
Sodium-translocating NADH dehydrogenase (ubiquinone) subunit nqrD; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.
 
 0.999
nqrE
Na+-translocating NADH:quinone oxidoreductase subunit nqrE; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family.
 
 0.999
nqrF
Na+-translocating NADH:quinone oxidoreductase, subunit nqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.
 
 0.998
RB9190
Ferredoxin; Best DB hits: BLAST: pir:E75319; ferredoxin - Deinococcus radiodurans (strain R1) -----; E=2e-18 pir:C83272; Na+-translocating NADH:quinone oxidoreductase, subunit; E=0.002 gb:AAD03987.1; (AF079317) xylene monooxygenase electron transfer; E=0.005 COG: DR2075; COG0633 Ferredoxin; E=2e-19 PA2994; COG2871 Na+-transporting NADH:ubiquinone oxidoreductase beta; E=2e-04 CPn0883; COG2871 Na+-transporting NADH:ubiquinone oxidoreductase; E=0.001 PFAM: PF00111; 2Fe-2S iron-sulfur cluster binding d; E=2.6e-05.
  
 
 0.906
metF
5,10-methylenetetrahydrofolate reductase; PMID: 99215588 PMID: 6356036 best DB hits: BLAST: swissprot:O67422; METF_AQUAE 5,10-METHYLENETETRAHYDROFOLATE; E=1e-57 pir:T47821; methylenetetrahydrofolate reductase MTHFR1 - Arabidopsis; E=6e-50 gb:AAD51733.1; AF174486_1 (AF174486) methylenetetrahydrofolate; E=6e-48 COG: aq_1429; COG0685 5,10-methylenetetrahydrofolate reductase; E=1e-58 PFAM: PF02219; Methylenetetrahydrofolate reductase; E=2.9e-97; Belongs to the methylenetetrahydrofolate reductase family.
      
 0.736
apbE
Thiamine biosynthesis lipoprotein apbE; PMID: 7542800 best DB hits: BLAST: pir:A82094; thiamin biosynthesis lipoprotein ApbE VC2289 [imported]; E=3e-61 swissprot:P44550; APBE_HAEIN THIAMINE BIOSYNTHESIS LIPOPROTEIN; E=8e-52 gb:AAK03418.1; (AE006171) ApbE [Pasteurella multocida]; E=4e-51 COG: VC2289; COG1477 Membrane-associated lipoprotein involved in thiamine; E=3e-62 NMB0563; COG1477 Membrane-associated lipoprotein involved in; E=2e-46 apbE; COG1477 Membrane-associated lipoprotein involved in thiamine; E=8e-45 PFAM: PF02424; ApbE family; E=6.5e-89.
 
   
 0.696
lldP
L-lactate permease; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
      
 0.685
glpA
PMID: 7821823 best DB hits: BLAST: pir:C75448; glycerol-3-phosphate dehydrogenase - Deinococcus; E=1e-112 pir:C70130; glycerol-3-phosphate dehydrogenase, anaerobic (glpA); E=4e-83 gb:AAF02807.1; AC009400_3 (AC009400) putative glycerol-3-phosphate; E=2e-82 COG: DR1019; COG0578 Glycerol-3-phosphate dehydrogenase; E=1e-113 PFAM: PF02737; 3-hydroxyacyl-CoA dehydrogenase; E=0.61 PF00070; Pyridine nucleotide-disulphide; E=0.036 PF02032; Phytoene dehydrogenase related; E=0.11; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
      
 0.651
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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