STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB1885Best DB hits: BLAST: pir:A71001; hypothetical protein PH1305 - Pyrococcus horikoshii; E=4e-13 pir:G75136; menaquinone biosynthesis methlytransferase related; E=9e-12 ddbj:BAB07674.1; (AP001520) BH3955~unknown conserved protein; E=2e-05 COG: PH1305; COG0500 SAM-dependent methyltransferases; E=4e-14. (293 aa)    
Predicted Functional Partners:
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.
    
 0.831
RB1887
Probable aldehyde dehydrogenase; Best DB hits: BLAST: pir:S27612; ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.-) -; E=2e-87 pir:S27619; ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.-) -; E=3e-86 pdb:1EYY; A Chain A, Crystal Structure Of The Nadp+ Dependent; E=8e-79 COG: PA2217; COG1012 NAD-dependent aldehyde dehydrogenases; E=9e-80 PFAM: PF00831; Ribosomal L29 protein; E=0.78 PF00171; Aldehyde dehydrogenase family; E=2.9e-07.
   
   0.733
RB386
Saframycin Mx1 synthetase B; PMID: 8936303 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-112 pir:T34918; polyketide synthase - Streptomyces coelicolor -----; E=1e-102 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=1e-101 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-102 Rv1529; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-83 Ta1189; COG0156 7-keto-8-aminopelargonate synthetase and related; E=6e-62 PFAM: PF00501; AMP-binding enzyme; E=2.2e-08 PF00550; Phosphopantetheine attac [...]
 
 0.693
rpsQ
Probable 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
  0.661
rpsH-2
30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family.
   
  0.654
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
    
  0.652
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
  0.650
rpsO
Probable 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
    
  0.648
rpsM
30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family.
    
  0.646
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
  0.612
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.