STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB2135Heparan N-sulfatase; PMID: 11181566 best DB hits: BLAST: gb:AAG41945.1; AF304053_1 (AF304053) heparan N-sulfatase [Mus; E=4e-62 gb:AAF29467.1; (AF156255) N-sulfoglucosamine sulfohydrolase [Mus; E=6e-62 gb:AAG41946.1; AF304054_1 (AF304054) mutant heparan N-sulfatase; E=1e-61 COG: Rv0296c; COG3119 Arylsulfatase A and related enzymes; E=7e-23 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=0.002 BS_yfnI; COG1368 Phosphoglycerol transferase and related proteins,; E=0.002 PFAM: PF00884; Sulfatase; E=7.8e-22. (488 aa)    
Predicted Functional Partners:
RB2132
Hypothetical protein-signal peptide and transmembrane prediction.
       0.773
RB2136
Hypothetical protein; Best DB hits: BLAST: gb:AAD26901.1; AC007267_1 (AC007267) putative leucine-rich repeat; E=0.011 gb:AAF82144.1; AC034256_8 (AC034256) Contains similarity to F-box; E=0.040 pir:T08903; hypothetical protein T32A16.10 - Arabidopsis thaliana; E=0.25.
       0.572
acrB
Acriflavine resistance protein B; PMID: 8905231 PMID: 8407802 PMID: 7651136 best DB hits: BLAST: pir:F83335; RND multidrug efflux transporter MexF PA2494 [imported] -; E=0.0 pir:T30830; hypothetical protein mexF - Pseudomonas aeruginosa -----; E=0.0 pir:D83206; probable RND efflux transporter PA3522 [imported] -; E=0.0 COG: PA2494; COG0841 Cation/multidrug efflux pump; E=0.0 PFAM: PF00873; AcrB/AcrD/AcrF family; E=0; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
      
 0.550
RB950
Amino acid transporter; PMID: 3146645 best DB hits: BLAST: swissprot:Q10858; YJ99_MYCTU HYPOTHETICAL 45.3 KDA TRANSPORT; E=2e-23 embl:CAB76881.1; (AL159139) putative amino acid transporter; E=2e-16 pir:G82809; amino acid transporter XF0408 [imported] - Xylella; E=3e-15 COG: Rv1999c; COG0531 Amino acid transporters; E=2e-24 BS_gabP; COG1113 Gamma-aminobutyrate and related permeases; E=2e-06 Rv3253c; COG0531 Amino acid transporters; E=4e-06 PFAM: PF00324; Amino acid permease; E=0.00042.
      
 0.540
RB2140
Hypothetical protein.
       0.464
RB5340
Conserved hypothetical protein; PMID: 11823852 best DB hits: BLAST: pir:A64656; hypothetical protein HP1089 - Helicobacter pylori; E=0.12 pir:C71944; hypothetical protein jhp0336 - Helicobacter pylori; E=0.76 ddbj:BAB06700.1; (AP001517) BH2981~unknown [Bacillus halodurans]; E=0.77.
  
     0.460
GALNS-6
Probable sulfatase atsG; PMID: 9634230 best DB hits: BLAST: gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=8e-20 ddbj:BAA04535.1; (D17629) N-acetylgalactosamine 6-sulfate; E=3e-18 pir:F70837; probable sulfatase (EC 3.1.6.-) atsG - Mycobacterium; E=2e-15 COG: Rv0296c; COG3119 Arylsulfatase A and related enzymes; E=2e-16 BS_yvgJ; COG1368 Phosphoglycerol transferase and related proteins,; E=0.001 PAB0793; COG2194 Predicted membrane-associated, metal-dependent; E=0.002 PFAM: PF01663; Type I phosphodiesterase / nucle; E=0.89 PF00884; Sulfatase; E=7.3e-28.
  
   
0.445
RB13157
Mucin-desulfating sulfatase; PMID: 9710560 PMID: 10809675 best DB hits: BLAST: gb:AAF72520.1; AF248951_1 (AF248951) mucin-desulfating sulfatase; E=6e-35 gb:AAF55296.1; (AE003712) Sulf1 gene product [Drosophila; E=2e-28 pir:T16584; hypothetical protein K09C4.8 - Caenorhabditis elegans; E=3e-24 COG: yidJ; COG3119 Arylsulfatase A and related enzymes; E=1e-24 BS_yqgS; COG1368 Phosphoglycerol transferase and related proteins,; E=0.007 PFAM: PF02455; Hexon-associated protein (IIIa); E=0.25 PF00884; Sulfatase; E=8e-47.
  
   
0.435
GALNS
N-acetylgalactosamine 6-sulfate sulfatase (GALNS); PMID: 1755850 PMID: 8001980 PMID: 1522213 best DB hits: BLAST: ddbj:BAA04535.1; (D17629) N-acetylgalactosamine 6-sulfate; E=1e-31 gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=4e-30 embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=8e-28 COG: ydeN; COG3119 Arylsulfatase A and related enzymes; E=3e-26 PFAM: PF00884; Sulfatase; E=7.7e-45.
  
   
0.427
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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