STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xseBSimilar to exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (139 aa)    
Predicted Functional Partners:
xseA
Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
  
 0.994
ggpP
PMID: 8016276,10617198 best DB hits: BLAST: pir:S74538; geranylgeranyl pyrophosphate synthase - Synechocystis; E=3e-37 ddbj:BAA82613.1; (AB016093) geranylgeranyl diphosphate synthase; E=1e-36 embl:CAC10561.1; (AJ249453) gpp synthase large subunit [Mentha x; E=1e-35 COG: slr0739; COG0142 Geranylgeranyl pyrophosphate synthase; E=3e-38 PFAM: PF00348; Polyprenyl synthetase; E=1.6e-83; Belongs to the FPP/GGPP synthase family.
  
  
 0.869
dxs
1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.833
rluA
PMID: 1630901,7493321 best DB hits: BLAST: swissprot:P39219; RLUA_ECOLI RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE; E=5e-15 gb:AAG54362.1; AE005182_11 (AE005182) orf, hypothetical protein; E=3e-14 pir:C82498; ribosomal large chain pseudouridine synthase A VCA0104; E=5e-14 COG: rluA; COG0564 Pseudouridylate synthases, 23S RNA-specific; E=5e-16 PFAM: PF00849; RNA pseudouridylate synthase; E=4.8e-31.
  
    0.813
nadK
Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.794
RB2147
Hypothetical protein.
       0.773
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
   
    0.652
RB5932
Polyprenyl synthetase; PMID: 8182085 PMID: 2198286 best DB hits: BLAST: pir:E71101; probable geranylgeranyl pyrophosphate synthetase -; E=9e-17 gb:AAD47627.1; (AF153713) octylprenyl diphosphate synthase-like; E=1e-16 swissprot:Q53479; IDSA_METTM BIFUNCTIONAL SHORT CHAIN ISOPRENYL; E=2e-15 COG: PH1072; COG0142 Geranylgeranyl pyrophosphate synthase; E=9e-18 AF0204; COG1852 Uncharacterized ArCR; E=3e-13 NMB0261; COG0142 Geranylgeranyl pyrophosphate synthase; E=4e-13 PFAM: PF01976; Protein of unknown function D; E=6e-24 PF00348; Polyprenyl synthetase; E=3.4e-09.
  
  
 0.595
RB2148
Hypothetical protein; PMID: 20075061 best DB hits: BLAST: ddbj:BAA89233.1; (AB021180) skeletal myosin heavy chain [Gallus; E=0.15 pir:A32491; myosin heavy chain 1, muscle - fruit fly (Drosophila; E=0.34 pir:B32491; myosin heavy chain 2, muscle - fruit fly (Drosophila; E=0.41.
       0.572
ruvA
Probable holliday junction DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
   
 0.552
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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