STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB2238Flavohemoprotein; PMID: 8125952 best DB hits: BLAST: swissprot:P39662; HMPA_ALCEU FLAVOHEMOPROTEIN (HEMOGLOBIN-LIKE; E=7e-29 swissprot:P49852; HMPA_BACSU FLAVOHEMOPROTEIN (HEMOGLOBIN-LIKE; E=2e-26 swissprot:P26353; HMPA_SALTY FLAVOHEMOPROTEIN (HEMOGLOBIN-LIKE; E=2e-26 COG: BS_hmp_2; COG1018 Flavodoxin reductases (ferredoxin-NADPH; E=1e-27 hmp_2; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases); E=5e-25 BH1058_2; COG1018 Flavodoxin reductases (ferredoxin-NADPH; E=5e-23 PFAM: PF00970; Oxidoreductase FAD-binding doma; E=3.5e-24 PF01794; Ferric reductase like transmemb; E=0.76 P [...] (438 aa)    
Predicted Functional Partners:
gltD
NADH-glutamate synthase small chain; PMID: 2643092 PMID: 3326786 best DB hits: BLAST: ddbj:BAA12742.1; (D85230) small subunit of NADH-dependent; E=1e-163 pir:T49818; probable glutamate synthase (NADPH) [imported] -; E=1e-162 pir:S74625; NADH-glutamate synthase small chain gltD - Synechocystis; E=1e-161 COG: sll1027; COG0493 NADPH-dependent glutamate synthase beta chain and; E=1e-162 PFAM: PF01494; FAD binding domain; E=0.013 PF02254; KTN NAD-binding domain; E=0.036 PF00984; UDP-glucose/GDP-mannose dehydr; E=0.28.
   
 0.977
RB1481
Conserved hypothetical protein; PMID: 10984043 best DB hits: BLAST: pir:E83580; conserved hypothetical protein PA0529 [imported] -; E=1e-34 pir:A69811; conserved hypothetical protein yflK - Bacillus subtilis; E=4e-32 pir:F83366; conserved hypothetical protein PA2229 [imported] -; E=2e-31 COG: PA0529; COG2258 Uncharacterized BCR; E=1e-35.
   
 0.940
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
 
 
 0.936
cypX
Probable cytochrome P450 T9E850; PMID: 20411542 best DB hits: BLAST: pir:T06288; probable cytochrome P450 T9E8.50 - Arabidopsis thaliana; E=5e-14 ddbj:BAA31438.1; (AB010393) ALK6 [Yarrowia lipolytica]; E=3e-13 pir:C81286; probable cytochrome P450 Cj1411c [imported] -; E=5e-13 COG: Cj1411c; COG2124 Cytochrome P450; E=4e-14 PFAM: PF00067; Cytochrome P450; E=1e-20.
  
 0.925
nifU
Nitrogen fixation protein NifU; PMID: 11016950 best DB hits: BLAST: gb:AAG20546.1; (AE005125) nitrogen fixation protein; NifU; E=2e-22 ddbj:BAB07187.1; (AP001518) nitrogen fixation protein [Bacillus; E=4e-16 swissprot:Q9X192; NIFU_THEMA NIFU-LIKE PROTEIN ----- pir:; E=4e-15 COG: VNG2472G; COG0822 NifU homologs involved in Fe-S cluster formation; E=2e-23 PFAM: PF01592; NifU-like N terminal domain; E=1e-22.
  
 0.906
nuoM
PMID: 7690854 best DB hits: BLAST: pir:H81796; NADH dehydrogenase (ubiquinone) (EC 1.6.5.3) chain M; E=1e-15 pir:E81220; NADH dehydrogenase I, M chain NMB0258 [imported] -; E=4e-15 swissprot:Q9ZCG0; NUOM_RICPR NADH DEHYDROGENASE I CHAIN M; E=3e-14 COG: NMB0258; COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); E=4e-16 PH1431; COG0651 Formate hydrogenlyase subunit 3; E=6e-13 HP1272; COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); E=3e-12 PFAM: PF00361; NADH-Ubiquinone/plastoquinone (co; E=2e-07.
   
 
 0.892
cysJ
PMID: 2550423 best DB hits: BLAST: pir:G70040; sulfite reductase (NADPH) (EC 1.8.1.2) flavoprotein yvgR; E=8e-80 ddbj:BAB04328.1; (AP001509) sulfite reductase (NADPH) [Bacillus; E=2e-79 gb:AAG57872.1; AE005504_4 (AE005504) sulfite reductase (NADPH),; E=4e-75 COG: BS_yvgR; COG0369 Sulfite reductase flavoprotein subunit; E=8e-81 PA3490; COG2878 Predicted alternative beta subunit of; E=2e-04 PFAM: PF00667; FAD binding domain; E=1.9e-14 PF00175; Oxidoreductase FAD/NAD-binding d; E=2.8e-35.
 
 
 0.799
noxA
Probable NADH oxidase; Best DB hits: BLAST: pir:B82434; probable NADH oxidase VCA0644 [imported] - Vibrio; E=1e-102 gb:AAK04884.1; AE006312_4 (AE006312) NADH oxidase [Lactococcus; E=3e-99 gb:AAB90837.1; (AE001077) NADH oxidase (noxA-3) [Archaeoglobus; E=2e-75 COG: VCA0644_1; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; E=5e-87 BH0613; COG1251 NAD(P)H-nitrite reductase; E=1e-18 PFAM: PF01266; D-amino acid oxidase; E=0.47 PF02032; Phytoene dehydrogenase related; E=0.14 PF00070; Pyridine nucleotide-disulphide; E=8.8e-72.
  
 
 0.747
RB11582
Cysteine desulfurase; PMID: 10908675 PMID: 7496536 PMID: 8482384 best DB hits: BLAST: pir:A71960; probable nitrogenase cofactor synthesis protein nifS -; E=1e-50 pir:D64547; iron-sulfur cofactor synthesis protein - Helicobacter; E=2e-50 swissprot:Q43884; NIFS_ANAAZ NIFS PROTEIN ----- gb: AAA87249.1; E=6e-49 COG: jhp0206; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; E=1e-51 PFAM: PF00266; Aminotransferase class-V; E=1.6e-60.
  
 0.700
nifS-3
Cysteine desulfurase NifS; PMID: 10930739 PMID: 2553733 best DB hits: BLAST: gb:AAG01802.1; AF276772_1 (AF276772) cysteine desulfurase NifS; E=4e-53 swissprot:P12623; NIFS_ANASP NIFS PROTEIN ----- pir: C34443; E=2e-50 swissprot:Q43884; NIFS_ANAAZ NIFS PROTEIN ----- gb: AAA87249.1; E=3e-50 COG: yfhO; COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; E=3e-51 PFAM: PF00266; Aminotransferase class-V; E=7.9e-47.
  
 0.700
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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