STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB2244Glutathione peroxidase; PMID: 11859360 best DB hits: BLAST: pir:T44271; glutathione peroxidase homolog [imported] -; E=4e-40 embl:CAB88451.1; (AL353815) putative glutathione peroxidase; E=4e-38 pir:F83541; probable glutathione peroxidase PA0838 [imported] -; E=5e-38 COG: PA0838; COG0386 Glutathione peroxidase; E=5e-39 PFAM: PF00255; Glutathione peroxidase; E=7e-54; Belongs to the glutathione peroxidase family. (192 aa)    
Predicted Functional Partners:
RB4396
Glutathione reductase; PMID: 7559423 best DB hits: BLAST: swissprot:P48638; GSHR_ANASP GLUTATHIONE REDUCTASE (GR) (GRASE); E=7e-50 embl:CAA12270.1; (AJ224977) ORF 4 [Sphingomonas sp. RW5]; E=2e-49 gb:AAK04944.1; AE006318_7 (AE006318) glutathione reductase (EC; E=6e-49 COG: gor; COG1249 Dihydrolipoamide dehydrogenase/glutathione; E=4e-49 PFAM: PF00996; GDP dissociation inhibitor; E=0.34 PF00070; Pyridine nucleotide-disulphide; E=3.3e-62 PF02852; Pyridine nucleotide-disulphide; E=3.4e-06.
  
 0.911
sodA
Superoxide dismutase, Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 0.708
RB3234
Possible gluconolactonase precursor; PMID: 1482681 best DB hits: BLAST: embl:CAB59581.1; (AL132662) possible gluconolactonase precursor; E=2e-26 pir:A75539; probable gluconolactonase - Deinococcus radiodurans; E=8e-20 pir:B82698; gluconolactonase precursor XF1297 [imported] - Xylella; E=8e-16 COG: DR0277; COG3386 Uncharacterized protein; E=8e-21.
 
      0.661
RB11489
Vulnibactin utilization protein VIUB; PMID: 8698519 PMID: 97000351 best DB hits: BLAST: embl:CAB59476.1; (AL132648) hypothetical protein SCI41.06; E=1e-31 swissprot:Q56743; VIUB_VIBVU VULNIBACTIN UTILIZATION PROTEIN VIUB; E=5e-31 swissprot:Q56646; VIUB_VIBCH VIBRIOBACTIN UTILIZATION PROTEIN VIUB; E=9e-30 COG: VC2210; COG2375 Siderophore-interacting protein; E=9e-31.
 
      0.574
katA
Catalase; PMID: 9358059 best DB hits: BLAST: gb:AAB26985.1; (L48340) catalase [Methylobacterium extorquens]; E=0.0 swissprot:Q59714; CATA_PSEPU CATALASE ----- gb: AAB88219.1; E=1e-152 swissprot:P48062; CATA_BORPE CATALASE ----- pir: S60757; E=1e-152 COG: PA4236; COG0753 Catalase; E=1e-153 PFAM: PF01334; Bacterioferritin; E=0.24 PF00199; Catalase; E=1.7e-261.
  
 
 0.554
RB2239
Probable short-chain dehydrogenase; PMID: 10984043 best DB hits: BLAST: pir:G75333; 3-oxoacyl-acyl carrier protein reductase - Deinococcus; E=1e-16 gb:AAB82041.1; (U59236) unknown [Synechococcus sp. PCC 7942]; E=1e-16 pir:E83152; probable short-chain dehydrogenase PA3957 [imported] -; E=4e-16 COG: DR1943; COG1028 Dehydrogenases with different specificities (related; E=9e-18 BH1506; COG0300 Short-chain dehydrogenases of various substrate; E=3e-15 VNG1341G; COG1028 Dehydrogenases with different specificities; E=3e-14 PFAM: PF00106; short chain dehydrogenase; E=9.2e-43; Belongs to the sho [...]
  
    0.536
RB2242
PMID: 10952301 best DB hits: BLAST: pir:G82383; oxidoreductase, short-chain dehydrogenasereductase; E=2e-20 gb:AAG54602.1; AE005204_12 (AE005204) putative oxidoreductase; E=7e-20 gb:AAF18286.1; (AF088897) oxidoreductase; orf4 [Zymomonas; E=6e-19 COG: VCA1057; COG0300 Short-chain dehydrogenases of various substrate; E=2e-21 slr0315; COG1028 Dehydrogenases with different specificities; E=7e-20 PA4148; COG1028 Dehydrogenases with different specificities (related; E=3e-18 PFAM: PF00106; short chain dehydrogenase; E=5.3e-49; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.527
prdX2
Peroxiredoxin 2; PMID: 9115640 best DB hits: BLAST: ref:XP_009063.1; TR00071480_p [Homo sapiens]; E=2e-62 swissprot:Q61171; PDX2_MOUSE PEROXIREDOXIN 2 (THIOREDOXIN; E=3e-62 swissprot:P32119; PDX2_HUMAN PEROXIREDOXIN 2 (THIOREDOXIN; E=4e-62 COG: PA0848; COG0450 Thiol - alkyl hydroperoxide reductases; E=4e-60 PFAM: PF00578; AhpC/TSA family; E=1e-71.
   
 
 0.504
guaA-2
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.496
trxB
Putative thioredoxin reductase; PMID: 8843436 best DB hits: BLAST: embl:CAB93736.1; (AL357613) putative thioredoxin reductase; E=2e-67 pir:H72322; thioredoxin reductase - Thermotoga maritima (strain; E=2e-27 ddbj:BAB07290.1; (AP001519) thioredoxin reductase (NADPH); E=1e-26 COG: TM0869; COG0492 Thioredoxin reductase/alkyl hydroperoxide reductase; E=2e-28 VNG1259G; COG0492 Thioredoxin reductase/alkyl hydroperoxide; E=1e-21 aq_500; COG0492 Thioredoxin reductase/alkyl hydroperoxide reductase; E=1e-20 PFAM: PF00027; Cyclic nucleotide-binding domai; E=1.6e-07 PF00732; GMC oxidoreductases; E [...]
  
  
 0.431
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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