STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uxuBD-mannonate oxidoreductase; PMID: 7610040 best DB hits: BLAST: pir:D83353; mannitol dehydrogenase PA2342 [imported] - Pseudomonas; E=1e-116 gb:AAC04472.1; (AF007800) mannitol dehydrogenase [Pseudomonas; E=1e-111 embl:CAA96356.1; (Z71688) ORF YNR073c [Saccharomyces cerevisiae]; E=1e-102 COG: PA2342; COG0246 Mannitol-1-phosphate/altronate dehydrogenases; E=1e-117 PFAM: PF01232; Mannitol dehydrogenase; E=9.3e-176. (502 aa)    
Predicted Functional Partners:
RB2404
Hypothetical protein-transmembrane prediction; PMID: 10086841.
     0.952
xylA
Xylose isomerase; PMID: 1368665 PMID: 9495747 best DB hits: BLAST: swissprot:P22842; XYLA_THEET XYLOSE ISOMERASE ----- pir:; E=1e-155 gb:AAC46145.1; (AF001974) xylose isomerase; XylA; E=1e-155 swissprot:P19148; XYLA_THETU XYLOSE ISOMERASE ----- pir:; E=1e-153 COG: BH2757; COG2115 Xylose isomerase; E=1e-149 PFAM: PF00259; Xylose isomerase; E=1.5e-221.
    
 0.930
fruA
Best DB hits: BLAST: ddbj:BAB04547.1; (AP001510) PTS system, fructose-specific enzyme; E=6e-19 gb:AAK05057.1; AE006330_5 (AE006330) fructose-specific PTS system; E=9e-18 ddbj:BAB03332.1; (AB035450) fructose specific permease; E=1e-16 COG: BH0828_1; COG1762 Phosphotransferase system; E=3e-19 TP0085; COG1762 Phosphotransferase system mannitol/fructose-specific; E=5e-16 NMB0736; COG1762 Phosphotransferase system; E=7e-14 PFAM: PF00359; Phosphoenolpyruvate-dependent suga; E=3.6e-13.
  
 
 0.930
scrK
Probable fructokinase; PMID: 1809835 PMID: 10411273 best DB hits: BLAST: gb:AAG60871.1; AF322012_176 (AF322013) ID402 [Bradyrhizobium; E=5e-08 gb:AAK03933.1; (AE006222) unknown [Pasteurella multocida]; E=2e-06 pir:G75112; fructokinase (EC 2.7.1.4) PAB0482 - Pyrococcus abyssi; E=2e-05 COG: PAB0482; COG0524 Sugar kinases, ribokinase family; E=2e-06 PFAM: PF00294; pfkB family carbohydrate kinase; E=2.5e-12.
    
 0.913
RB12360
Levanase precursor; PMID: 3112519 PMID: 2117666 best DB hits: BLAST: pir:A27286; levanase (EC 3.2.1.65) precursor - Bacillus subtilis; E=3e-54 swissprot:P05656; SACC_BACSU LEVANASE PRECURSOR; E=3e-54 prf:1404371A; levanase [Bacillus subtilis]; E=3e-54 COG: BS_sacC; COG1621 Beta-fructosidases (levanase/invertase); E=3e-55 PFAM: PF00251; Glycosyl hydrolases family 32; E=4.6e-10 PF02012; BNR repeat; E=0.81 PF00251; Glycosyl hydrolases family 32; E=3.1e-15.
     
 0.907
RB5320
Probable zinc-type alcohol dehydrogenase; PMID: 3622514 best DB hits: BLAST: ddbj:BAA75341.1; (AB011837) sorbitol dehydrogenase [Bacillus; E=8e-44 swissprot:P77539; YDJL_ECOLI HYPOTHETICAL ZINC-TYPE ALCOHOL; E=7e-35 gb:AAG56765.1; AE005400_10 (AE005400) putative oxidoreductase; E=9e-35 COG: BH0189; COG1063 Threonine dehydrogenase and related Zn-dependent; E=7e-45 PFAM: PF00107; Zinc-binding dehydrogenases; E=6.5e-60.
    
 0.906
adh-3
Probable alcohol dehydrogenase (Zn-dependent); PMID: 3622514 best DB hits: BLAST: prf:2104227E; 2,3-butanediol dehydrogenase [Pseudomonas putida]; E=3e-40 pir:C83128; 2,3-butanediol dehydrogenase PA4153 [imported] -; E=4e-40 ddbj:BAB03906.1; (AP001507) sorbitol dehydrogenase [Bacillus; E=1e-38 COG: PA4153; COG1063 Threonine dehydrogenase and related Zn-dependent; E=4e-41 Rv3086; COG1062 Zn-dependent alcohol dehydrogenases, class III; E=7e-26 PFAM: PF00107; Zinc-binding dehydrogenases; E=4.4e-92.
    
 0.906
RB10616
Altronate hydrolase; PMID: 9278503 PMID: 3038546 best DB hits: BLAST: ddbj:BAB04209.1; (AP001508) altronate hydrolase [Bacillus; E=6e-65 gb:AAG58224.1; AE005539_1 (AE005539) altronate hydrolase; E=2e-64 swissprot:P42604; UXAA_ECOLI ALTRONATE HYDROLASE (ALTRONIC ACID; E=2e-63 COG: BH0490; COG2721 Altronate dehydratase; E=6e-66.
  
 0.885
RB6095
Conserved hypothetical protein; PMID: 10484179 best DB hits: BLAST: ddbj:BAB04212.1; (AP001508) BH0493~unknown [Bacillus halodurans]; E=4e-12 gb:AAF77061.1; AF266466_3 (AF266466) putative hexuronic acid; E=0.003 gb:AAK05726.1; AE006393_5 (AE006393) glucuronate isomerase (EC; E=0.57.
  
  
 0.514
RB2408
Conserved hypothetical protein; PMID: 9687406 best DB hits: BLAST: embl:CAB61226.1; (Y17305) hypothetical protein [Bacillus; E=2e-15 swissprot:P43965; YAFM_HAEIN HYPOTHETICAL PROTEIN HI0217 -----; E=4e-04 pir:E81971; hypothetical protein NMA0532 [imported] - Neisseria; E=4e-04 COG: HI0217; COG1943 Predicted transposase; E=3e-05 PFAM: PF00637; 7-fold repeat in Clathrin and; E=0.77 PF02178; AT hook motif; E=0.72.
       0.488
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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