STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nagBGlucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (251 aa)    
Predicted Functional Partners:
nagA
N-acetylglucosamine-6-phosphate deacetylase; PMID: 2668691 PMID: 2190615 best DB hits: BLAST: pir:C70845; probable nagA protein - Mycobacterium tuberculosis; E=2e-33 gb:AAK05433.1; AE006366_2 (AE006366); E=1e-32 gb:AAG58267.1; AE005542_9 (AE005542) putative; E=2e-32 COG: Rv3332; COG1820 N-acetylglucosamine-6-phosphate deacetylase; E=2e-34 Ta1060; COG0402 Cytosine deaminase and related metal-dependent; E=0.001 yicP; COG1001 Adenine deaminase; E=0.002 PFAM: PF01979; Adenine deaminase; E=0.071 PF01685; Chlorohydrolase; E=0.002 PF01979; Adenine deaminase; E=8.9e-07.
 0.985
nagA-2
N-acetylglucosamine-6-phosphate deacetylase NAGA; PMID: 9634230 best DB hits: BLAST: pir:C70845; probable nagA protein - Mycobacterium tuberculosis; E=8e-23 embl:CAB93044.1; (AL357432) putative deacetylase [Streptomyces; E=2e-19 swissprot:O34450; NAGA_BACSU N-ACETYLGLUCOSAMINE-6-PHOSPHATE; E=5e-18 COG: Rv3332; COG1820 N-acetylglucosamine-6-phosphate deacetylase; E=7e-24 PFAM: PF02612; N-acetylglucosamine-6-phosphate deac; E=5.6e-05.
 0.980
pgi
Glucose-6-phosphate isomerase; PMID: 2549364 best DB hits: BLAST: swissprot:P80860; G6PI_BACSU GLUCOSE-6-PHOSPHATE ISOMERASE (GPI); E=6e-53 ddbj:BAB07062.1; (AP001518) glucose-6-phosphate isomerase; E=4e-52 pir:S15937; glucose-6-phosphate isomerase (EC 5.3.1.9) - Bacillus; E=5e-52 COG: BS_pgi; COG0166 Glucose-6-phosphate isomerase; E=6e-54 PFAM: PF00342; Phosphoglucose isomerase; E=6.8e-31.
  
 0.911
scrK
Probable fructokinase; PMID: 1809835 PMID: 10411273 best DB hits: BLAST: gb:AAG60871.1; AF322012_176 (AF322013) ID402 [Bradyrhizobium; E=5e-08 gb:AAK03933.1; (AE006222) unknown [Pasteurella multocida]; E=2e-06 pir:G75112; fructokinase (EC 2.7.1.4) PAB0482 - Pyrococcus abyssi; E=2e-05 COG: PAB0482; COG0524 Sugar kinases, ribokinase family; E=2e-06 PFAM: PF00294; pfkB family carbohydrate kinase; E=2.5e-12.
  
 
 0.902
pmi
PMID: 8293960 best DB hits: BLAST: pir:B75598; probable mannose-6-phosphate isomerase - Deinococcus; E=7e-43 pir:H69848; mannose-6-phosphate isomerase homolog yjdE - Bacillus; E=5e-39 ddbj:BAA75351.1; (AB011838) mannnose-6 phospate isomelase; E=8e-39 COG: DRA0048; COG1482 Phosphomannose isomerase; E=7e-44 PFAM: PF01238; Phosphomannose isomerase type I; E=0.0026.
     
 0.901
RB2533
Probable integral membrane protein; PMID: 8843436 best DB hits: BLAST: embl:CAB88464.1; (AL353815) putative integral membrane protein; E=2e-07 pir:S74882; hypothetical protein sll1151 - Synechocystis sp. (strain; E=3e-07 gb:AAB90453.1; (AE001050) conserved hypothetical protein; E=1e-04 COG: sll1151; COG1808 Uncharacterized ACR; E=3e-08.
       0.773
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 
 0.709
RB2529
Hypothetical protein-signal peptide and transmembrane prediction.
       0.701
RB2530
Conserved hypothetical protein-putative oxidoreductase; Best DB hits: BLAST: gb:AAG19823.1; (AE005067) Vng1537c [Halobacterium sp. NRC-1]; E=4e-27 pir:E75148; hypothetical protein PAB2116 - Pyrococcus abyssi (strain; E=9e-25 gb:AAG20566.1; (AE005127) Vng2502c [Halobacterium sp. NRC-1]; E=8e-24 COG: VNG1537C; COG1078 HD superfamily phosphohydrolases; E=4e-28.
       0.701
RB2534
Hypothetical protein.
       0.565
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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