STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB2728PMID: 8552028 best DB hits: BLAST: pir:D82244; sensory box sensor histidine kinase VC1084 [imported] -; E=4e-15 ddbj:BAB05639.1; (AP001513) two-component sensor histidine kinase; E=1e-13 pir:S60595; FixL protein - Rhizobium leguminosarum ----- gb:; E=3e-13 COG: VC1084; COG0642 Sensory transduction histidine kinases; E=3e-16 PFAM: PF00672; HAMP domain; E=2.9e-10 PF00512; His Kinase A (phosphoacceptor) doma; E=3.2e-08 PF02518; Histidine kinase-, DNA gyrase B-, p; E=7.9e-33. (673 aa)    
Predicted Functional Partners:
RB10488
PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42.
 
 0.985
RB641
Sensory histidine protein kinase; Best DB hits: BLAST: pir:G82753; two-component system, sensor protein XF0853 [imported] -; E=2e-41 gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=8e-39 pir:A82300; sensory box sensor histidine kinaseresponse regulator; E=4e-34 COG: XF0853; COG0642 Sensory transduction histidine kinases; E=2e-42 sll0779_1; COG2202 PAS/PAC domain; E=1e-23 VCA0736_1; COG0642 Sensory transduction histidine kinases; E=1e-23 PFAM: PF00785; PAC motif; E=8.5e-08 PF00989; PAS domain; E=0.013 PF00785; PAC motif; E=0.1.
 
 
0.971
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 
0.958
RB13175
PMID: 2201868 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-67 pir:S75142; sensory transduction histidine kinase slr1759 -; E=2e-55 embl:CAA65047.1; (X95731) putative sensor kinase [Synechocystis; E=3e-55 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-50 PFAM: PF00989; PAS domain; E=0.011 PF00785; PAC motif; E=0.075 PF00989; PAS domain; E=0.46.
 
 
 
0.957
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 
0.956
RB3373
PMID: 9098081 best DB hits: BLAST: pir:T28655; receptor-like histidine kinase BpdS - Rhodococcus sp; E=1e-60 pir:T30898; receptor-like histidine kinase - Rhodococcus erythropolis; E=1e-60 pir:S75136; sensory transduction histidine kinase slr2104 -; E=9e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-41 PFAM: PF00069; Protein kinase domain; E=8.1e-08 PF00515; TPR Domain; E=0.026 PF00512; His Kinase A (phosphoacceptor); E=1.4e-21.
 
 
0.954
RB8873
PMID: 7984107 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-56 pir:S75525; sensory transduction histidine kinase sll1228 -; E=4e-50 pir:E82198; sensor histidine kinaseresponse regulator VC1445; E=5e-46 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=2e-43 PFAM: PF00785; PAC motif; E=0.00017 PF00512; His Kinase A (phosphoacceptor; E=1.1e-25 PF02518; Histidine kinase-, DNA gyrase; E=8.9e-44.
 
 
0.952
RB159
PMID: 11406410 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-69 pir:S75130; sensory transduction histidine kinase slr2098 -; E=4e-63 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=8e-62 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=2e-53 PFAM: PF00989; PAS domain; E=5.9e-05 PF00512; His Kinase A (phosphoacceptor); E=4.2e-24 PF02518; Histidine kinase-, DNA gyrase B; E=4.1e-43.
 
 
0.951
RB10330
Best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-69 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-56 pir:H83132; probable sensorresponse regulator hybrid PA4112; E=1e-52 COG: PA4982; COG0642 Sensory transduction histidine kinases; E=4e-49 PFAM: PF00512; His Kinase A (phosphoacceptor) d; E=1.3e-22 PF02518; Histidine kinase-, DNA gyrase B-; E=8e-46 PF00072; Response regulator receiver doma; E=6.2e-33.
 
 
0.950
RB5477
Probable two component system response regulator; PMID: 1454550 best DB hits: BLAST: pir:T17197; adenylate cyclase homolog - Spirulina platensis -----; E=2e-09 gb:AAD30120.2; (AF135389) DNA binding response regulator RpaA; E=2e-08 pir:S75923; sensory transduction system regulatory protein sll1555 -; E=4e-08 COG: slr2024; COG0784 CheY-like receiver domains; E=9e-09 slr0115; COG0745 Response regulators consisting of a CheY-like; E=1e-08 TP0519; COG2204 AAA superfamily ATPases with N-terminal receiver; E=2e-08 PFAM: PF00072; Response regulator receiver doma; E=2.4e-10.
 
 
 0.949
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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