STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB2794Deoxyribonuclease gamma [precursor]; PMID: 9665719 best DB hits: BLAST: gb:AAC64266.1; (AF059612) deoxyribonuclease gamma [Xenopus; E=1e-19 gb:AAB00496.1; (L40823) DNL1L gene product [Homo sapiens]; E=5e-17 gb:AAB17022.1; (U06846) XIB [Homo sapiens]; E=7e-17 PFAM: PF01181; Deoxyribonuclease I (DNase I); E=1.3e-10. (341 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.829
dnaN
DNA polymerase III, beta chain; PMID: 2540413 best DB hits: BLAST: swissprot:P13455; DP3B_PSEPU DNA POLYMERASE III, BETA CHAIN; E=1e-31 pir:C81713; DNA polymerase III, beta chain TC0347 [imported] -; E=1e-29 pir:E71559; probable DNA pol III (beta chain) - Chlamydia; E=1e-29 COG: CT075; COG0592 DNA polymerase III beta subunit; E=1e-30 PFAM: PF00712; DNA polymerase III beta subun; E=7.1e-16 PF02767; DNA polymerase III beta subun; E=2.4e-12 PF02768; DNA polymerase III beta subun; E=1e-10.
   
 0.764
dnlI
Thermostable DNA ligase; PMID: 8843436 best DB hits: BLAST: embl:CAC01484.1; (AL391017) putative DNA ligase [Streptomyces; E=5e-32 swissprot:P56709; DNLI_PYRFU THERMOSTABLE DNA LIGASE; E=4e-30 embl:CAC21199.1; (AJ133713) DNA ligase [Thermococcus fumicolans]; E=4e-29 COG: VNG0881G; COG1793 ATP-dependent DNA ligase; E=5e-29 PFAM: PF01068; DNA ligase; E=1.2e-28.
  
 
 0.753
mutY
A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.
    
 0.720
RB2247
Conserved hypothetical protein; Best DB hits: BLAST: gb:AAG19229.1; (AE005019) Vng0754c [Halobacterium sp. NRC-1]; E=9e-06 gb:AAF75279.1; AF265353_1 (AF265353) byssal protein Dpfp1; E=0.21 ddbj:BAA94345.1; (AB035520) parchorin [Oryctolagus cuniculus]; E=0.50 PFAM: PF00089; Trypsin; E=0.58.
 
    0.713
alkA
DNA-3-methyladenine glycosidase; PMID: 8921872 PMID: 91092284 PMID: 89024568 best DB hits: BLAST: pir:T08409; DNA-3-methyladenine glycosidase I homolog F18B3.160 -; E=9e-20 gb:AAD39589.1; AC007858_3 (AC007858) This gene is a member of PF; E=2e-19 ddbj:BAB05468.1; (AP001513) DNA-3-methyladenine glycosidase; E=4e-19 COG: BH1749; COG0122 3-Methyladenine DNA glycosylase; E=4e-20.
  
 0.708
RB11529
Probable beta-1,4 N-acetylgalactosaminyltransferase; PMID: 1601877 best DB hits: BLAST: gb:AAA35516.1; (M83651) beta-1,4; E=6e-07 ddbj:BAA04632.1; (D17809) beta-4N-acetylgalactosaminyltransferase; E=2e-06 gb:AAA39802.1; (L30104) N-acetylgalactosaminyltransferase [Mus; E=2e-06 COG: BS_yveT; COG0463 Glycosyltransferases involved in cell wall; E=0.003 PFAM: PF00535; Glycosyl transferase; E=5.2e-08.
  
     0.663
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
  
 0.644
mpg
N-methylpurine-DNA glycosirase (MPG); PMID: 95134354 best DB hits: BLAST: embl:CAA52615.1; (X74509) N-methylpurine-DNA glycosirase (MPG); E=9e-26 pdb:1F4R; A Chain A, Crystal Structure Of The Human Aag Dna Repair; E=3e-22 gb:AAA58369.1; (M71215) alkyl-N-purine-DNA glycosylasee [Homo; E=5e-22 COG: APE2247; COG2094 3-methyladenine DNA glycosylase; E=8e-18 PFAM: PF02245; Methylpurine-DNA glycosylase (M; E=2.2e-44.
 
  
 0.622
RB5501
Hypothetical protein.
  
 0.619
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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