STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chlIPMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. (482 aa)    
Predicted Functional Partners:
hemH
Probable ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.933
hemY
Protoporphyrinogen IX and coproporphyrinogen III oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
   
 
 0.911
hemG
Protoporphyrinogen oxidase; PMID: 7916647 PMID: 7788523 best DB hits: BLAST: gb:AAA67647.1; (M87049) o181 [Escherichia coli]; E=1e-22 swissprot:P27863; HEMG_ECOLI PROTOPORPHYRINOGEN OXIDASE (PPO); E=2e-22 pir:S30741; hypothetical protein o181 - Escherichia coli; E=4e-22 COG: hemG; COG0716 Flavodoxins; E=2e-23 PFAM: PF00258; Flavodoxin; E=0.00015.
     
  0.900
RB12936
Conserved hypothetical protein; PMID: 10567266 best DB hits: BLAST: pir:H75280; conserved hypothetical protein - Deinococcus radiodurans; E=5e-27 swissprot:P71551; Y959_MYCTU HYPOTHETICAL 74.6 KDA PROTEIN RV0959; E=5e-21 gb:AAB89815.1; (AE001004) A. fulgidus predicted coding region; E=0.013 COG: AF1444; COG2304 Protein containing von Willebrand factor (vWF) type; E=0.001.
    0.828
secA
PMID: 2542029 best DB hits: BLAST: pir:F82760; preprotein translocase SecA subunit XF0806 [imported] -; E=3e-73 ddbj:BAB07325.1; (AP001519) preprotein translocase subunit; E=1e-72 swissprot:P28366; SECA_BACSU PREPROTEIN TRANSLOCASE SECA SUBUNIT; E=7e-69 COG: XF0806; COG0653 Preprotein translocase subunit SecA (ATPase, RNA; E=3e-74 PFAM: PF01043; SecA protein, amino terminal reg; E=1e-16 PF00271; Helicase conserved C-terminal do; E=0.12.
      
 0.601
secA-2
Preprotein translocase secA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
      
 0.601
SecA
Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
      
 0.550
dnaX
DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
      
 0.548
dnaB
PMID: 6323420 best DB hits: BLAST: pir:E83029; replicative DNA helicase PA4931 [imported] - Pseudomonas; E=6e-04 swissprot:Q9ZJM5; DNAB_HELPJ REPLICATIVE DNA HELICASE -----; E=0.002 gb:AAK00231.1; AF229444_1 (AF229444) replicative DNA helicase DnaB; E=0.003 COG: PA4931; COG0305 Replicative DNA helicase; E=6e-05 PFAM: PF00772; DnaB-like helicase; E=4.3e-05.
      
 0.543
dnaB-2
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
      
 0.543
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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