node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RB12936 | chlI | RB12936 | RB309 | Conserved hypothetical protein; PMID: 10567266 best DB hits: BLAST: pir:H75280; conserved hypothetical protein - Deinococcus radiodurans; E=5e-27 swissprot:P71551; Y959_MYCTU HYPOTHETICAL 74.6 KDA PROTEIN RV0959; E=5e-21 gb:AAB89815.1; (AE001004) A. fulgidus predicted coding region; E=0.013 COG: AF1444; COG2304 Protein containing von Willebrand factor (vWF) type; E=0.001. | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | 0.828 |
SecA | chlI | RB11690 | RB309 | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | 0.550 |
SecA | dnaB-2 | RB11690 | RB1708 | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.469 |
SecA | dnaX | RB11690 | RB6494 | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.456 |
SecA | secA | RB11690 | RB148 | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | PMID: 2542029 best DB hits: BLAST: pir:F82760; preprotein translocase SecA subunit XF0806 [imported] -; E=3e-73 ddbj:BAB07325.1; (AP001519) preprotein translocase subunit; E=1e-72 swissprot:P28366; SECA_BACSU PREPROTEIN TRANSLOCASE SECA SUBUNIT; E=7e-69 COG: XF0806; COG0653 Preprotein translocase subunit SecA (ATPase, RNA; E=3e-74 PFAM: PF01043; SecA protein, amino terminal reg; E=1e-16 PF00271; Helicase conserved C-terminal do; E=0.12. | 0.919 |
SecA | secA-2 | RB11690 | RB2013 | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Preprotein translocase secA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.914 |
chlI | RB12936 | RB309 | RB12936 | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | Conserved hypothetical protein; PMID: 10567266 best DB hits: BLAST: pir:H75280; conserved hypothetical protein - Deinococcus radiodurans; E=5e-27 swissprot:P71551; Y959_MYCTU HYPOTHETICAL 74.6 KDA PROTEIN RV0959; E=5e-21 gb:AAB89815.1; (AE001004) A. fulgidus predicted coding region; E=0.013 COG: AF1444; COG2304 Protein containing von Willebrand factor (vWF) type; E=0.001. | 0.828 |
chlI | SecA | RB309 | RB11690 | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.550 |
chlI | dnaB | RB309 | RB12211 | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | PMID: 6323420 best DB hits: BLAST: pir:E83029; replicative DNA helicase PA4931 [imported] - Pseudomonas; E=6e-04 swissprot:Q9ZJM5; DNAB_HELPJ REPLICATIVE DNA HELICASE -----; E=0.002 gb:AAK00231.1; AF229444_1 (AF229444) replicative DNA helicase DnaB; E=0.003 COG: PA4931; COG0305 Replicative DNA helicase; E=6e-05 PFAM: PF00772; DnaB-like helicase; E=4.3e-05. | 0.543 |
chlI | dnaB-2 | RB309 | RB1708 | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.543 |
chlI | dnaX | RB309 | RB6494 | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.548 |
chlI | hemG | RB309 | RB4887 | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | Protoporphyrinogen oxidase; PMID: 7916647 PMID: 7788523 best DB hits: BLAST: gb:AAA67647.1; (M87049) o181 [Escherichia coli]; E=1e-22 swissprot:P27863; HEMG_ECOLI PROTOPORPHYRINOGEN OXIDASE (PPO); E=2e-22 pir:S30741; hypothetical protein o181 - Escherichia coli; E=4e-22 COG: hemG; COG0716 Flavodoxins; E=2e-23 PFAM: PF00258; Flavodoxin; E=0.00015. | 0.900 |
chlI | hemH | RB309 | RB8233 | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | Probable ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.933 |
chlI | hemY | RB309 | RB10459 | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | Protoporphyrinogen IX and coproporphyrinogen III oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.911 |
chlI | secA | RB309 | RB148 | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | PMID: 2542029 best DB hits: BLAST: pir:F82760; preprotein translocase SecA subunit XF0806 [imported] -; E=3e-73 ddbj:BAB07325.1; (AP001519) preprotein translocase subunit; E=1e-72 swissprot:P28366; SECA_BACSU PREPROTEIN TRANSLOCASE SECA SUBUNIT; E=7e-69 COG: XF0806; COG0653 Preprotein translocase subunit SecA (ATPase, RNA; E=3e-74 PFAM: PF01043; SecA protein, amino terminal reg; E=1e-16 PF00271; Helicase conserved C-terminal do; E=0.12. | 0.601 |
chlI | secA-2 | RB309 | RB2013 | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | Preprotein translocase secA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.601 |
dnaB | chlI | RB12211 | RB309 | PMID: 6323420 best DB hits: BLAST: pir:E83029; replicative DNA helicase PA4931 [imported] - Pseudomonas; E=6e-04 swissprot:Q9ZJM5; DNAB_HELPJ REPLICATIVE DNA HELICASE -----; E=0.002 gb:AAK00231.1; AF229444_1 (AF229444) replicative DNA helicase DnaB; E=0.003 COG: PA4931; COG0305 Replicative DNA helicase; E=6e-05 PFAM: PF00772; DnaB-like helicase; E=4.3e-05. | PMID: 8663186 best DB hits: BLAST: pir:G75255; probable magnesium protoporphyrin chelatase -; E=3e-84 pir:D70717; hypothetical protein Rv0958 - Mycobacterium tuberculosis; E=4e-69 gb:AAF82071.1; AF232750_3 (AF232750) Rv0958-like protein; E=2e-25 COG: DR2594; COG1239 Mg-chelatase subunit ChlI; E=2e-85 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=1.1e-12. | 0.543 |
dnaB | dnaB-2 | RB12211 | RB1708 | PMID: 6323420 best DB hits: BLAST: pir:E83029; replicative DNA helicase PA4931 [imported] - Pseudomonas; E=6e-04 swissprot:Q9ZJM5; DNAB_HELPJ REPLICATIVE DNA HELICASE -----; E=0.002 gb:AAK00231.1; AF229444_1 (AF229444) replicative DNA helicase DnaB; E=0.003 COG: PA4931; COG0305 Replicative DNA helicase; E=6e-05 PFAM: PF00772; DnaB-like helicase; E=4.3e-05. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.900 |
dnaB | dnaX | RB12211 | RB6494 | PMID: 6323420 best DB hits: BLAST: pir:E83029; replicative DNA helicase PA4931 [imported] - Pseudomonas; E=6e-04 swissprot:Q9ZJM5; DNAB_HELPJ REPLICATIVE DNA HELICASE -----; E=0.002 gb:AAK00231.1; AF229444_1 (AF229444) replicative DNA helicase DnaB; E=0.003 COG: PA4931; COG0305 Replicative DNA helicase; E=6e-05 PFAM: PF00772; DnaB-like helicase; E=4.3e-05. | DNA polymerase III gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.772 |
dnaB-2 | SecA | RB1708 | RB11690 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.469 |