STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysASulfate transport ATP-binding protein cysA; PMID: 2188958 best DB hits: BLAST: gb:AAF43869.1; AF166114_81 (AF166114) probable transport protein; E=3e-22 gb:AAG19353.1; (AE005030) spermidineputrescine ABC transporter; E=7e-22 pir:B81966; probable ABC transport ATP-binding protein NMA0485; E=7e-22 COG: VNG0921G; COG1130 ABC-type sugar/spermidine/putrescine transport; E=6e-23 NMB1966; COG1127 Uncharacterized ABC-type transport system, ATPase; E=9e-23 slr1455; COG1118 ABC-type sulfate/molybdate transport systems,; E=3e-22 PFAM: PF01078; Magnesium chelatase, subunit Chl; E=0.58 PF00005; ABC [...] (527 aa)    
Predicted Functional Partners:
RB12506
Probable anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); PMID: 9266669 best DB hits: BLAST: ddbj:BAB05255.1; (AP001512) anti-sigma F factor antagonist (stage; E=0.003 pir:S75220; hypothetical protein slr1912 - Synechocystis sp. (strain; E=0.024 COG: BH1536; COG1366 Anti-anti-sigma regulatory factor (antagonist of; E=3e-04 PFAM: PF01740; STAS domain; E=4.9e-06.
   
   0.999
RB7131
Hypothetical protein; PMID: 93377076 best DB hits: PFAM: PF02470; mce related protein; E=1.5e-09.
  
 
 0.999
RB7135
Probable permease of ABC transporter; PMID: 10984043 best DB hits: BLAST: pir:G71718; hypothetical protein RP096 - Rickettsia prowazekii; E=4e-38 pir:E70331; conserved hypothetical protein aq_355 - Aquifex aeolicus; E=6e-37 pir:S74989; hypothetical protein slr1045 - Synechocystis sp. (strain; E=5e-35 COG: RP096; COG0767 Permease component of an ABC-transporter; E=3e-39 PFAM: PF02405; Domain of unknown function DUF140; E=4.8e-79; Belongs to the MlaE permease family.
 
 0.959
RB7134
PMID: 10710307 best DB hits: BLAST: pir:G81022; ABC transporter, ATP-binding protein NMB1966 [imported]; E=1e-40 pir:B81966; probable ABC transport ATP-binding protein NMA0485; E=2e-40 swissprot:O06784; MKL_MYCTU POSSIBLE RIBONUCLEOTIDE TRANSPORT; E=1e-38 COG: NMB1966; COG1127 Uncharacterized ABC-type transport system, ATPase; E=1e-41 PA2350; COG1135 Uncharacterized ABC-type transport system ATPase; E=1e-32 XF0421; COG1127 Uncharacterized ABC-type transport system, ATPase; E=3e-32 PFAM: PF00006; ATP synthase alpha/beta family, n; E=0.092 PF00485; Phosphoribulokinase / Uridine kin; E=0. [...]
 
 
0.946
RB2547
Hypothetical protein-signal peptide prediction; PMID: 11214968 best DB hits: BLAST: gb:AAG20070.1; (AE005086) Vng1869c [Halobacterium sp. NRC-1]; E=0.18.
  
  
  0.919
ptfA
Probable fructose specific permease-possibly phosphotransferase system component; PMID: 20175229 best DB hits: BLAST: ddbj:BAB03332.1; (AB035450) fructose specific permease; E=3e-07 pir:H69626; PTS fructose-specific enzyme IIBC component fruA -; E=5e-07 pir:B81941; probable regulatory protein NMA0946 [imported] -; E=9e-07 COG: BS_fruA_1; COG1762 Phosphotransferase system; E=5e-08 TP0755; COG1762 Phosphotransferase system mannitol/fructose-specific; E=6e-07 VC1826_1; COG1762 Phosphotransferase system; E=8e-07.
 
     0.719
RB3291
Hypothetical protein.
       0.714
RB3371
Conserved hypothetical protein; PMID: 9634230 best DB hits: BLAST: swissprot:Q10552; Y893_MYCTU HYPOTHETICAL 36.1 KDA PROTEIN RV0893C; E=3e-10 swissprot:Q50726; YX99_MYCTU HYPOTHETICAL 38.1 KDA PROTEIN RV3399; E=2e-08 pir:A70645; hypothetical protein Rv0726c - Mycobacterium; E=6e-08 COG: Rv0893c; COG3315 O-Methyltransferase involved in polyketide; E=3e-11 PFAM: PF02409; Domain of unknown function DUF142; E=7e-05; Belongs to the UPF0677 family.
  
     0.706
RB3253
Probable ABC-type transport system ATP-binding protein; Best DB hits: BLAST: ddbj:BAA75396.1; (AB013378) YhaQ [Bacillus halodurans]; E=1e-38 pir:T36523; probable ABC-type transport system ATP-binding protein -; E=2e-38 ddbj:BAB04722.1; (AP001510) ABC transporter (ATP-binding protein); E=4e-38 COG: BH1003; COG1131 ABC-type multidrug transport system, ATPase; E=3e-39 PFAM: PF01495; HypB/UreG nucleotide-binding; E=0.28 PF02223; Thymidylate kinase; E=0.38 PF00005; ABC transporter; E=2.4e-41.
 
   
 0.705
RB6865
Hypothetical protein.
  
     0.703
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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