STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB3309N-acetylgalactosamine 6-sulfatase (GALNS); PMID: 8020961 best DB hits: BLAST: ddbj:BAA04535.1; (D17629) N-acetylgalactosamine 6-sulfate; E=3e-39 gb:AAF63858.1; (AF112242) N-acetylgalactosamine-6-sulfate; E=3e-33 embl:CAA36398.1; (X52150) arylsulphatase a [Homo sapiens]; E=9e-32 COG: aslA; COG3119 Arylsulfatase A and related enzymes; E=1e-19 VC2041; COG3083 Predicted hydrolase of alkaline phosphatase; E=0.007 PFAM: PF00884; Sulfatase; E=4.4e-58. (684 aa)    
Predicted Functional Partners:
RB3312
Conserved hypothetical protein-putative ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
       0.773
RB406
PMID: 10809675 best DB hits: BLAST: gb:AAF72520.1; AF248951_1 (AF248951) mucin-desulfating sulfatase; E=4e-37 pir:F83354; probable sulfatase PA2333 [imported] - Pseudomonas; E=2e-19 gb:AAF55296.1; (AE003712) Sulf1 gene product [Drosophila; E=2e-18 COG: PA2333; COG3119 Arylsulfatase A and related enzymes; E=1e-20 yejM; COG3083 Predicted hydrolase of alkaline phosphatase; E=7e-04 BS_yfnI; COG1368 Phosphoglycerol transferase and related proteins,; E=0.001 PFAM: PF00325; Bacterial regulatory proteins, crp; E=0.29 PF00884; Sulfatase; E=4.3e-51.
  
     0.647
RB3305
Hypothetical protein-putative transmembrane protein.
       0.504
RB5383
Probable sulfatase atsG; PMID: 10950929 best DB hits: BLAST: pir:F70837; probable sulfatase (EC 3.1.6.-) atsG - Mycobacterium; E=8e-23 gb:AAG41945.1; AF304053_1 (AF304053) heparan N-sulfatase [Mus; E=1e-20 gb:AAF29467.1; (AF156255) N-sulfoglucosamine sulfohydrolase [Mus; E=2e-20 COG: Rv0296c; COG3119 Arylsulfatase A and related enzymes; E=8e-24 PFAM: PF00884; Sulfatase; E=5.2e-13.
  
     0.504
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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