STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB3313PMID: 10952301 best DB hits: BLAST: pir:E82042; conserved hypothetical protein VC2716 [imported] -; E=0.0 swissprot:P57072; YHGF_NEIMA HYPOTHETICAL PROTEIN NMA0194 -----; E=1e-179 swissprot:P71353; YHGF_HAEIN HYPOTHETICAL PROTEIN HI0568 -----; E=1e-177 COG: VC2716; COG2183 Predicted RNA binding protein, contains S1 domain; E=0.0 Rv1630; COG0539 Ribosomal protein S1; E=2e-06 BS_comEA; COG1555 DNA uptake protein and related DNA-binding; E=3e-06 PFAM: PF00633; Helix-hairpin-helix motif; E=0.51 PF00575; S1 RNA binding domain; E=4.4e-25. (750 aa)    
Predicted Functional Partners:
rpoA-2
PMID: 9835038 best DB hits: BLAST: swissprot:O50634; RPOA_BACHD DNA-DIRECTED RNA POLYMERASE ALPHA; E=2e-09 swissprot:Q9Z3E7; RPOA_XANCP DNA-DIRECTED RNA POLYMERASE ALPHA; E=4e-09 gb:AAD00325.2; (U79735) RNA polymerase ALPHA subunit [Xanthomonas; E=4e-09 COG: BH0162; COG0202 DNA-directed RNA polymerase alpha subunit/40 kD; E=2e-10 PFAM: PF00515; TPR Domain; E=0.87 PF01000; Bacterial RNA polymerase, alpha; E=6.5e-12.
    
 0.894
rpoB
DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.866
rpoZ
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.861
ftsH
PMID: 8444796 best DB hits: BLAST: pir:F72009; cell division protein FtsH, probable CP0857 [imported] -; E=2e-04 pir:D71463; probable ATP-dependent zinc proteinase - Chlamydia; E=4e-04 pir:F81725; cell division protein FtsH, probable TC0229 [imported] -; E=5e-04 COG: CPn0998; COG0465 ATP-dependent Zn proteases; E=2e-05 PFAM: PF01434; Peptidase family M41; E=0.4.
       0.773
RB3317
PMID: 9584149 best DB hits: BLAST: gb:AAC23913.1; (AF039207) NADH-dependent dehydrogenase homolog; E=3e-13 pir:B72359; lipopolysaccharide biosynthesis protein BplA -; E=2e-12 embl:CAC24034.1; (AL512980) ORF-c34_017 [Sulfolobus solfataricus]; E=2e-08 COG: TM0585; COG0673 Predicted dehydrogenases and related proteins; E=2e-13 PFAM: PF01408; Oxidoreductase family, NAD-bin; E=1.1e-12.
       0.509
rpoA
DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.463
rpoA-3
PMID: 3093467 best DB hits: BLAST: swissprot:P20429; RPOA_BACSU DNA-DIRECTED RNA POLYMERASE ALPHA; E=1e-07 gb:AAA81287.1; (U30821) alpha subunit of RNA polymerase; E=5e-07 swissprot:O50634; RPOA_BACHD DNA-DIRECTED RNA POLYMERASE ALPHA; E=1e-06 COG: BS_rpoA; COG0202 DNA-directed RNA polymerase alpha subunit/40 kD; E=1e-08 PFAM: PF01000; Bacterial RNA polymerase, alpha; E=8.2e-15.
    
 0.463
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.