STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsHPMID: 8444796 best DB hits: BLAST: pir:F72009; cell division protein FtsH, probable CP0857 [imported] -; E=2e-04 pir:D71463; probable ATP-dependent zinc proteinase - Chlamydia; E=4e-04 pir:F81725; cell division protein FtsH, probable TC0229 [imported] -; E=5e-04 COG: CPn0998; COG0465 ATP-dependent Zn proteases; E=2e-05 PFAM: PF01434; Peptidase family M41; E=0.4. (194 aa)    
Predicted Functional Partners:
RB3313
PMID: 10952301 best DB hits: BLAST: pir:E82042; conserved hypothetical protein VC2716 [imported] -; E=0.0 swissprot:P57072; YHGF_NEIMA HYPOTHETICAL PROTEIN NMA0194 -----; E=1e-179 swissprot:P71353; YHGF_HAEIN HYPOTHETICAL PROTEIN HI0568 -----; E=1e-177 COG: VC2716; COG2183 Predicted RNA binding protein, contains S1 domain; E=0.0 Rv1630; COG0539 Ribosomal protein S1; E=2e-06 BS_comEA; COG1555 DNA uptake protein and related DNA-binding; E=3e-06 PFAM: PF00633; Helix-hairpin-helix motif; E=0.51 PF00575; S1 RNA binding domain; E=4.4e-25.
       0.773
hpt
Hypoxanthine-guanine phosphoribosyltransferase; PMID: 10192928 best DB hits: BLAST: pir:T36331; probable hypoxanthine phosphoribosyltransferase -; E=6e-27 ddbj:BAB03803.1; (AP001507) hypoxanthine-guanine; E=8e-23 embl:CAB60853.1; (AL132877) predicted using Genefinder; E=1e-22 COG: BH0084; COG0634 Hypoxanthine-guanine phosphoribosyltransferase; E=7e-24 BU169; COG0462 Phosphoribosylpyrophosphate synthetase; E=0.002 APE2071; COG2236 Predicted phosphoribosyltransferases; E=0.007 PFAM: PF00156; Phosphoribosyl transferase domai; E=1.5e-15; Belongs to the purine/pyrimidine phosphoribosyltrans [...]
  
  
 0.703
clpX
ATP-dependent Clp protease ATP-binding subunit clpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
   
  
 0.642
folE
GTP cyclohydrolase I; PMID: 1551827 PMID: 95352066 best DB hits: BLAST: swissprot:P19465; GCH1_BACSU GTP CYCLOHYDROLASE I (GTP-CH-I); E=1e-59 ddbj:BAB05365.1; (AP001512) GTP cyclohydrolase I [Bacillus; E=1e-57 swissprot:O06273; GCH1_MYCTU GTP CYCLOHYDROLASE I (GTP-CH-I); E=4e-53 COG: BS_mtrA; COG0302 GTP cyclohydrolase I; E=1e-60 PFAM: PF01227; GTP cyclohydrolase I; E=2.3e-110.
  
  
 0.568
RB3317
PMID: 9584149 best DB hits: BLAST: gb:AAC23913.1; (AF039207) NADH-dependent dehydrogenase homolog; E=3e-13 pir:B72359; lipopolysaccharide biosynthesis protein BplA -; E=2e-12 embl:CAC24034.1; (AL512980) ORF-c34_017 [Sulfolobus solfataricus]; E=2e-08 COG: TM0585; COG0673 Predicted dehydrogenases and related proteins; E=2e-13 PFAM: PF01408; Oxidoreductase family, NAD-bin; E=1.1e-12.
       0.509
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 
 0.486
rplO
50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
   0.486
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.474
rpmA
50S ribosomal protein L27; PMID: 10617197 PMID: 1225626 best DB hits: BLAST: gb:AAC64229.1; (AC005167) 50S ribosomal protein L27 [Arabidopsis; E=4e-19 swissprot:O87885; RL27_LAWIN 50S RIBOSOMAL PROTEIN L27 -----; E=1e-18 pir:T49957; ribosomal protein L27-like - Arabidopsis thaliana; E=2e-18 COG: VC0436; COG0211 Ribosomal protein L27; E=2e-18 PFAM: PF01016; Ribosomal L27 protein; E=6.4e-44; Belongs to the bacterial ribosomal protein bL27 family.
  
 
 0.474
rplQ
Probable 50S ribosomal protein L17; PMID: 2989779 PMID: 10094780 best DB hits: BLAST: swissprot:Q9Z9H5; RL17_THETH 50S RIBOSOMAL PROTEIN L17 -----; E=7e-11 pir:B75313; ribosomal protein L17 - Deinococcus radiodurans (strain; E=3e-09 swissprot:Q9ZCT0; RL17_RICPR 50S RIBOSOMAL PROTEIN L17 -----; E=3e-09 COG: DR2129; COG0203 Ribosomal protein L17; E=2e-10 PFAM: PF01196; Ribosomal protein L17; E=4.2e-06.
   
 
 0.472
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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