STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB3363Probable transcriptional regulatory protein fixJ; PMID: 2000090 PMID: 8552028 best DB hits: BLAST: pir:S77202; sensory transduction histidine kinase sll1687 -; E=1e-09 swissprot:Q46791; YGEK_ECOLI HYPOTHETICAL TRANSCRIPTIONAL; E=5e-07 swissprot:P23221; FIXJ_BRAJA TRANSCRIPTIONAL REGULATORY PROTEIN; E=5e-07 COG: sll1687_1; COG2202 PAS/PAC domain; E=1e-10 ygeK; COG2771 DNA-binding HTH domains; E=4e-08 sll0779_1; COG2202 PAS/PAC domain; E=2e-07 PFAM: PF00989; PAS domain; E=0.032 PF00785; PAC motif; E=4.6e-09 PF00196; Bacterial regulatory proteins, luxR; E=1.4e-19. (474 aa)    
Predicted Functional Partners:
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.963
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.962
RB10488
PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42.
 
 
 0.950
RB13175
PMID: 2201868 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-67 pir:S75142; sensory transduction histidine kinase slr1759 -; E=2e-55 embl:CAA65047.1; (X95731) putative sensor kinase [Synechocystis; E=3e-55 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=1e-50 PFAM: PF00989; PAS domain; E=0.011 PF00785; PAC motif; E=0.075 PF00989; PAS domain; E=0.46.
 
 
 0.946
RB641
Sensory histidine protein kinase; Best DB hits: BLAST: pir:G82753; two-component system, sensor protein XF0853 [imported] -; E=2e-41 gb:AAA98756.1; (L29642) sensor kinase [Pseudomonas fluorescens]; E=8e-39 pir:A82300; sensory box sensor histidine kinaseresponse regulator; E=4e-34 COG: XF0853; COG0642 Sensory transduction histidine kinases; E=2e-42 sll0779_1; COG2202 PAS/PAC domain; E=1e-23 VCA0736_1; COG0642 Sensory transduction histidine kinases; E=1e-23 PFAM: PF00785; PAC motif; E=8.5e-08 PF00989; PAS domain; E=0.013 PF00785; PAC motif; E=0.1.
 
 
 0.945
RB8873
PMID: 7984107 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-56 pir:S75525; sensory transduction histidine kinase sll1228 -; E=4e-50 pir:E82198; sensor histidine kinaseresponse regulator VC1445; E=5e-46 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=2e-43 PFAM: PF00785; PAC motif; E=0.00017 PF00512; His Kinase A (phosphoacceptor; E=1.1e-25 PF02518; Histidine kinase-, DNA gyrase; E=8.9e-44.
 
 
 0.945
RB13181
PMID: 2201868 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=8e-57 pir:E82198; sensor histidine kinaseresponse regulator VC1445; E=4e-49 embl:CAA37397.1; (X53315) arcB [Escherichia coli]; E=3e-48 COG: sll1353_2; COG0642 Sensory transduction histidine kinases; E=7e-43 PFAM: PF00785; PAC motif; E=0.1 PF00989; PAS domain; E=8.8e-05 PF00785; PAC motif; E=9.8e-08.
 
 
 0.943
RB13112
PMID: 7984107 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=1e-69 pir:S75130; sensory transduction histidine kinase slr2098 -; E=4e-57 pir:C82424; sensor histidine kinase LuxQ VCA0736 [imported] - Vibrio; E=8e-56 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=8e-57 PFAM: PF00785; PAC motif; E=0.34 PF00512; His Kinase A (phosphoacceptor) d; E=8.1e-23 PF02518; Histidine kinase-, DNA gyrase B-; E=3.6e-41.
 
 
 0.942
rpfC
Best DB hits: BLAST: pir:S75525; sensory transduction histidine kinase sll1228 -; E=3e-62 pir:S75136; sensory transduction histidine kinase slr2104 -; E=5e-60 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=1e-58 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=9e-60 PFAM: PF00989; PAS domain; E=0.025 PF00785; PAC motif; E=0.012 PF00989; PAS domain; E=7.5e-05.
 
 
 0.941
RB11986
Histidine protein kinase homolog GacS; PMID: 10762268 best DB hits: BLAST: gb:AAF04854.1; AF197912_1 (AF197912) histidine protein kinase; E=3e-57 pir:E83212; probable sensorresponse regulator hybrid PA3462; E=4e-56 pir:H83132; probable sensorresponse regulator hybrid PA4112; E=8e-51 COG: PA3462; COG0642 Sensory transduction histidine kinases; E=3e-57 PFAM: PF00989; PAS domain; E=3.5e-07 PF00512; His Kinase A (phosphoacceptor; E=2.5e-21 PF02518; Histidine kinase-, DNA gyrase; E=6.8e-39.
 
 
 0.938
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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