STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB3476Conserved hypothetical protein; PMID: 8688087 best DB hits: BLAST: swissprot:Q58408; YA02_METJA HYPOTHETICAL PROTEIN MJ1002 -----; E=4e-23 pir:F75071; hypothetical protein PAB1730 - Pyrococcus abyssi (strain; E=3e-22 pir:B71094; hypothetical protein PH1015 - Pyrococcus horikoshii; E=2e-21 COG: MJ1002; COG1624 Uncharacterized ACR; E=4e-24 PFAM: PF02457; Domain of unknown function DUF147; E=1.2e-26. (331 aa)    
Predicted Functional Partners:
RB6328
Adenylyl cyclase related protein; PMID: 9371463 best DB hits: BLAST: pir:F69084; conserved hypothetical protein MTH1629 -; E=1e-20 pir:C71193; hypothetical protein PH1819 - Pyrococcus horikoshii; E=8e-18 swissprot:Q57692; Y240_METJA HYPOTHETICAL PROTEIN MJ0240 -----; E=1e-17 COG: MTH1629; COG1437 Adenylate cyclase, class 2 (thermophilic); E=1e-21 PFAM: PF01928; Adenylate cyclase; E=2.9e-45.
 
   
 0.667
pmm
Phosphomannomutase; PMID: 8083177 best DB hits: BLAST: gb:AAD56627.1; AF165218_2 (AF165218) Pgm [Streptococcus; E=2e-83 ddbj:BAB04825.1; (AP001510) phosphomannomutase [Bacillus; E=5e-79 swissprot:P18159; YHXB_BACSU PROBABLE PHOSPHOMANNOMUTASE (PMM); E=1e-77 COG: BH1106; COG1109 Phosphomannomutase; E=5e-80 VC2095; COG0033 Phosphoglucomutase; E=3e-11 PH0923; COG1109 Phosphomannomutase; E=5e-11 PFAM: PF02878; Phosphoglucomutase/phosphomannomu; E=1.6e-13 PF02880; Phosphoglucomutase/phosphomannomu; E=0.023 PF00408; Phosphoglucomutase/phosphomannomu; E=0.76.
 
 
 
 0.582
RB2247
Conserved hypothetical protein; Best DB hits: BLAST: gb:AAG19229.1; (AE005019) Vng0754c [Halobacterium sp. NRC-1]; E=9e-06 gb:AAF75279.1; AF265353_1 (AF265353) byssal protein Dpfp1; E=0.21 ddbj:BAA94345.1; (AB035520) parchorin [Oryctolagus cuniculus]; E=0.50 PFAM: PF00089; Trypsin; E=0.58.
 
     0.579
RB10473
Best DB hits: BLAST: pir:D71687; alkaline proteinase secretion protein apre (aprE) RP314; E=0.032 pir:E82263; conserved hypothetical protein VC0913 [imported] -; E=0.053 gb:AAK03081.1; (AE006139) unknown [Pasteurella multocida]; E=0.13 COG: RP314; COG0845 Membrane-fusion protein; E=0.003 PFAM: PF01590; GAF domain; E=0.00029 PF00364; Biotin-requiring enzyme; E=0.0022.
  
     0.525
RB6596
Hypothetical protein.
  
     0.510
RB3473
Hypothetical protein-transmembrane prediction.
       0.487
RB1793
Conserved hypothetical protein; PMID: 10360571 best DB hits: BLAST: pir:F72424; hypothetical protein - Thermotoga maritima (strain MSB8); E=0.098.
  
     0.479
RB5140
Probable NADH-dependent dehydrogenase; PMID: 8472911 best DB hits: BLAST: embl:CAB02496.1; (Z80356) glucose-fructose oxidoreductase; E=2e-07 pdb:1OFG; A Chain A, Glucose-Fructose Oxidoreductase -----; E=2e-07 pdb:1EVJ; A Chain A, Crystal Structure Of Glucose-Fructose; E=2e-07 COG: BH1248; COG0673 Predicted dehydrogenases and related proteins; E=1e-05 PFAM: PF01408; Oxidoreductase family, NAD-bindi; E=3.2e-09.
  
     0.479
RB2654
Similar to membrane spanning export protein; PMID: 11206551 best DB hits: BLAST: gb:AAG54840.1; AE005229_3 (AE005229) putative membrane spanning; E=0.072 gb:AAG09745.1; AF232237_3 (AF232237) membrane fusion protein; E=0.23 pir:E70342; cation efflux system (czcB-like) - Aquifex aeolicus; E=0.43 PFAM: PF00364; Biotin-requiring enzyme; E=0.0014 PF00529; HlyD family secretion protein; E=2.9e-05.
  
     0.474
RB9832
Phosphomannomutase (pmm); Best DB hits: BLAST: pir:E71082; probable phospho-sugar mutase 2 - Pyrococcus horikoshii; E=1e-60 pir:H75104; phosphomannomutase (pmm) PAB0819 - Pyrococcus abyssi; E=7e-58 gb:AAB90779.1; (AE001073) phosphomannomutase (pmm) [Archaeoglobus; E=5e-53 COG: PH0923; COG1109 Phosphomannomutase; E=1e-61 PFAM: PF02878; Phosphoglucomutase/phosphomannomu; E=4.1e-29 PF02879; Phosphoglucomutase/phosphomannomu; E=1.2e-15 PF02880; Phosphoglucomutase/phosphomannomu; E=0.00028.
   
 
 0.474
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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