STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (442 aa)    
Predicted Functional Partners:
xseB
Similar to exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
  
 0.994
folD
5,20-methylene-tetrahyrdofolate dehydrogenase (NADP+) / methylentetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
    0.934
nifU
Nitrogen fixation protein NifU; PMID: 11016950 best DB hits: BLAST: gb:AAG20546.1; (AE005125) nitrogen fixation protein; NifU; E=2e-22 ddbj:BAB07187.1; (AP001518) nitrogen fixation protein [Bacillus; E=4e-16 swissprot:Q9X192; NIFU_THEMA NIFU-LIKE PROTEIN ----- pir:; E=4e-15 COG: VNG2472G; COG0822 NifU homologs involved in Fe-S cluster formation; E=2e-23 PFAM: PF01592; NifU-like N terminal domain; E=1e-22.
   
   0.788
RB3597
NifS protein homolog yurW; PMID: 9384377 PMID: 2644218 PMID: 3040672 PMID: 8464885 PMID: 8161529 best DB hits: BLAST: pir:T35993; probable aminotransferase - Streptomyces coelicolor; E=3e-98 pir:S76601; hypothetical protein - Synechocystis sp. (strain PCC; E=1e-97 pir:F70019; nifS protein homolog yurW - Bacillus subtilis -----; E=3e-95 COG: slr0077; COG0520 Selenocysteine lyase; E=1e-98 PFAM: PF00266; Aminotransferase class-V; E=7.2e-16.
       0.773
kel
Ring canal kelch protein; PMID: 8453663 PMID: 9118811 best DB hits: BLAST: gb:AAF53651.1; (AE003657) kel gene product [Drosophila; E=8e-17 swissprot:Q04652; KELC_DROME RING CANAL KELCH PROTEIN [CONTAINS:; E=8e-17 gb:AAA53471.1; (L08483) ring canal protein [Drosophila; E=1e-15 PFAM: PF01344; Kelch motif; E=2.6e-07.
       0.773
sodA
Superoxide dismutase, Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 0.635
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
  
 0.616
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.573
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
 
   
 0.553
RB1900
Probable NusG-like protein-putative transcription activator; PMID: 9919671 best DB hits: BLAST: embl:CAA09920.1; (AJ012097) NusG-like protein [Myxococcus; E=3e-05 pir:G82255; probable transcription activator RfaH VC0990 [imported]; E=4e-04 embl:CAA10615.1; (AJ132239) transcriptional activator [Erwinia; E=0.019 COG: VC0990; COG0250 Transcription antiterminator; E=3e-05.
   
    0.540
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.