STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB3605Conserved hypothetical protein-putative response regulator; PMID: 9384377 best DB hits: BLAST: pir:H83386; conserved hypothetical protein PA2072 [imported] -; E=1e-82 swissprot:P55552; Y4LL_RHISN HYPOTHETICAL 91.8 KD PROTEIN Y4LL; E=9e-82 pir:C83070; conserved hypothetical protein PA4601 [imported] -; E=7e-81 COG: PA2072_4; COG2200 Diguanylate cyclase/phosphodiesterase domain 2; E=2e-52 yddU_3; COG2200 Diguanylate cyclase/phosphodiesterase domain 2 (EAL); E=1e-45 PA0575_4; COG2200 Diguanylate cyclase/phosphodiesterase domain 2; E=2e-44 PFAM: PF00072; Response regulator receiver doma; E [...] (614 aa)    
Predicted Functional Partners:
RB4511
Sensory transduction histidine kinase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.975
RB10924
Probable sensor/response regulator hybrid; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.940
RB9418
Signal-transducing histidine kinase; Best DB hits: BLAST: swissprot:Q9R6X3; PHYB_ANASP CYANOBACTERIAL PHYTOCHROME B -----; E=5e-32 gb:AAB89763.1; (AE001000) signal-transducing histidine kinase; E=7e-28 pir:C75276; sensory box sensor histidine kinase - Deinococcus; E=5e-25 COG: DR2419_2; COG0642 Sensory transduction histidine kinases; E=5e-26 PFAM: PF00989; PAS domain; E=1.5e-06 PF00785; PAC motif; E=0.00034 PF00512; His Kinase A (phosphoacceptor) doma; E=1.3e-11.
  
 
 0.930
RB10488
PMID: 20572072 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-67 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-64 pir:H82211; sensory box sensor histidine kinaseresponse regulator; E=8e-61 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=7e-62 PFAM: PF00785; PAC motif; E=0.00076 PF00512; His Kinase A (phosphoacceptor) d; E=1.6e-28 PF02518; Histidine kinase-, DNA gyrase B-; E=1.6e-42.
 
 0.908
fixL
Probable sensor protein fixL; PMID: 2046550 PMID: 1766374 best DB hits: BLAST: gb:AAD12184.1; (U57900) utilizing regulatory protein tutC; E=4e-13 swissprot:P26489; FIXL_AZOCA SENSOR PROTEIN FIXL ----- pir:; E=6e-13 ddbj:BAA89701.1; (AB030079) 145..153:the transposed position of; E=7e-13 COG: VNG1464G_1; COG2202 PAS/PAC domain; E=4e-11 BH0536; COG0642 Sensory transduction histidine kinases; E=4e-11 BS_ytvA_1; COG2202 PAS/PAC domain; E=2e-09 PFAM: PF00989; PAS domain; E=0.00031 PF00785; PAC motif; E=3e-08 PF02518; Histidine kinase-, DNA gyrase B-; E=8e-26.
  
 
 0.881
RB4759
Sensor protein fixL; PMID: 2046550 PMID: 1766374 best DB hits: BLAST: swissprot:P26489; FIXL_AZOCA SENSOR PROTEIN FIXL -----pir:; E=2e-48 swissprot:P23222; FIXL_BRAJA SENSOR PROTEIN FIXL ----- pir:; E=8e-45 swissprot:P10955; FIXL_RHIME SENSOR PROTEIN FIXL ----- pir:; E=2e-43 COG: BS_ykrQ_3; COG0642 Sensory transduction histidine kinases; E=3e-27 PFAM: PF00989; PAS domain; E=1.3e-13 PF00785; PAC motif; E=0.052 PF00512; His Kinase A (phosphoacceptor) doma; E=4.1e-09.
  
 
 0.880
flgE
Flagellar hook protein FlgE; PMID: 10368149 best DB hits: BLAST: gb:AAD24206.1; AF049342_4 (AF049342) flagellar hook protein FlgE; E=8e-22 gb:AAA61738.1; (U19712) flagellar hook polypeptide [Borrelia; E=1e-21 gb:AAA91361.1; (U12870) flagellar distal rod protein [Borrelia; E=3e-21 COG: BB0283; COG1749 Flagellar basal body and hook proteins; E=5e-22 PFAM: PF00460; Flagella basal body rod protein; E=3.7e-10.
  
  
 0.876
RB10330
Best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=3e-69 pir:E83443; probable sensorresponse regulator hybrid PA1611; E=2e-56 pir:H83132; probable sensorresponse regulator hybrid PA4112; E=1e-52 COG: PA4982; COG0642 Sensory transduction histidine kinases; E=4e-49 PFAM: PF00512; His Kinase A (phosphoacceptor) d; E=1.3e-22 PF02518; Histidine kinase-, DNA gyrase B-; E=8e-46 PF00072; Response regulator receiver doma; E=6.2e-33.
 
 0.848
RB8873
PMID: 7984107 best DB hits: BLAST: pir:S75136; sensory transduction histidine kinase slr2104 -; E=2e-56 pir:S75525; sensory transduction histidine kinase sll1228 -; E=4e-50 pir:E82198; sensor histidine kinaseresponse regulator VC1445; E=5e-46 COG: VC1349_2; COG0642 Sensory transduction histidine kinases; E=2e-43 PFAM: PF00785; PAC motif; E=0.00017 PF00512; His Kinase A (phosphoacceptor; E=1.1e-25 PF02518; Histidine kinase-, DNA gyrase; E=8.9e-44.
 
 0.846
RB10892
Putative ammonium transporter; PMID: 8590279 best DB hits: BLAST: swissprot:P54148; Y537_SYNY3 PUTATIVE AMMONIUM TRANSPORTER SLL0537; E=9e-88 swissprot:P54147; Y108_SYNY3 PUTATIVE AMMONIUM TRANSPORTER SLL0108; E=1e-70 gb:AAB89503.1; (AE000982) ammonium transporter (amt-2); E=2e-66 COG: sll0537; COG0004 Ammonia permeases; E=8e-89 VC1084; COG0642 Sensory transduction histidine kinases; E=2e-33 MTH661; COG0004 Ammonia permeases; E=1e-32 PFAM: PF00909; Ammonium Transporter Family; E=1.9e-133 PF00512; His Kinase A (phosphoacceptor; E=6.1e-05 PF02518; Histidine kinase-, DNA gyrase; E=3.7e-25.
 
 
 0.843
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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