STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB3641Conserved hypothetical protein-putative cycloisomerase; PMID: 9384377 best DB hits: BLAST: swissprot:O34499; YKGB_BACSU HYPOTHETICAL 38.4 KDA PROTEIN IN; E=2e-41 embl:CAB66198.1; (AL136502) hypothetical protein SCF43.09; E=2e-41 pir:A83120; conserved hypothetical protein PA4204 [imported] -; E=9e-41 COG: BS_ykgB; COG2706 3-carboxymuconate cyclase; E=2e-42 PFAM: PF01453; Lectin (probable mannose binding); E=0.047. (671 aa)    
Predicted Functional Partners:
RB3635
Probable secreted glycosyl hydrolase; PMID: 8843436 best DB hits: BLAST: embl:CAB94634.1; (AL359215) putative secreted glycosyl hydrolase; E=4e-06 pir:T34929; hypothetical protein SC3F9.07 SC3F9.07 - Streptomyces; E=3e-05 pir:T35028; probable glycosyl hydrolase - Streptomyces coelicolor; E=2e-04.
 
     0.801
RB3639
Conserved hypothetical protein; PMID: 9384377 best DB hits: BLAST: pir:C69797; conserved hypothetical protein yesT - Bacillus subtilis; E=4e-27 gb:AAF25818.1; AF184175_1 (AF184175) cephalosporin C deacetylase; E=2e-23 pir:H69797; rhamnogalacturonan acetylesterase homolog yesY -; E=2e-22.
       0.773
RB11506
Probable 4-oxalocrotonate tautomerase; PMID: 1732207 PMID: 8547259 best DB hits: BLAST: swissprot:P45418; YKDK_ERWCH HYPOTHETICAL 8.1 KD PROTEIN IN KDGK; E=3e-06 pir:H81078; 4-oxalocrotonate tautomerase, probable NMB1474; E=8e-06 gb:AAG42543.1; (AY013584) putative isomerase [Sinorhizobium; E=2e-04 COG: NMB1474; COG1942 Uncharacterized protein, 4-oxalocrotonate; E=8e-07 PFAM: PF01361; Tautomerase enzyme; E=1.2e-06.
      
 0.680
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
  
 0.634
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
      
 0.631
xylA
Xylose isomerase; PMID: 1368665 PMID: 9495747 best DB hits: BLAST: swissprot:P22842; XYLA_THEET XYLOSE ISOMERASE ----- pir:; E=1e-155 gb:AAC46145.1; (AF001974) xylose isomerase; XylA; E=1e-155 swissprot:P19148; XYLA_THETU XYLOSE ISOMERASE ----- pir:; E=1e-153 COG: BH2757; COG2115 Xylose isomerase; E=1e-149 PFAM: PF00259; Xylose isomerase; E=1.5e-221.
     
 0.628
RB6095
Conserved hypothetical protein; PMID: 10484179 best DB hits: BLAST: ddbj:BAB04212.1; (AP001508) BH0493~unknown [Bacillus halodurans]; E=4e-12 gb:AAF77061.1; AF266466_3 (AF266466) putative hexuronic acid; E=0.003 gb:AAK05726.1; AE006393_5 (AE006393) glucuronate isomerase (EC; E=0.57.
     
 0.611
ugdH
UDP-glucose 6-dehydrogenase; PMID: 8938413 best DB hits: BLAST: pir:T51527; UDP-glucose dehydrogenase-like protein - Arabidopsis; E=1e-155 ddbj:BAB02581.1; (AP001309) UDP-glucose dehydrogenase; E=1e-151 swissprot:Q96558; UGDH_SOYBN UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC; E=1e-150 COG: aq_024; COG1004 Predicted UDP-glucose 6-dehydrogenase; E=2e-61 VC0918; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; E=1e-27 PA3540; COG1004 Predicted UDP-glucose 6-dehydrogenase; E=8e-26 PFAM: PF00984; UDP-glucose/GDP-mannose dehydro; E=2.6e-180; Belongs to the UDP-glucose/GDP-mannose dehydrogena [...]
      
 0.607
rhaA
L-rhamnose isomerase; PMID: 8396120 PMID: 10891278 best DB hits: BLAST: pir:B48649; L-rhamnose isomerase (EC 5.3.1.14) - Escherichia coli; E=1e-145 embl:CAA43002.1; (X60472) L-rhamnose isomerase [Escherichia coli]; E=1e-145 pdb:1DE5; A Chain A, L-Rhamnose Isomerase ----- pdb: 1DE5 B; E=1e-145.
      
 0.602
RB3633
Hypothetical protein.
       0.572
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (18%) [HD]