STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB3967Probable sodium/proline symporter (proline permease); PMID: 8031825 best DB hits: BLAST: gb:AAG20007.1; (AE005081) pantothenate permease; PanF; E=2e-20 pir:C69115; sodiumproline symporter (proline permease) -; E=3e-11 pir:B69833; metabolite permease homolog yhjB - Bacillus subtilis; E=7e-11 COG: VNG1785G; COG0591 Na+/proline, Na+/panthothenate symporters and; E=2e-21 panF; COG0591 Na+/proline, Na+/panthothenate symporters and related; E=3e-04 NMB0402; COG0591 Na+/proline, Na+/panthothenate symporters and; E=7e-04 PFAM: PF00474; Sodium:solute symporter family; E=0.11; Belongs to the sod [...] (544 aa)    
Predicted Functional Partners:
putA
PMID: 96062224 best DB hits: BLAST: pir:H64526; proline dehydrogenase (EC 1.5.99.8); E=0.0 pir:B71980; proline dehydrogenase (EC 1.5.99.8); E=0.0 pir:C81297; proline dehydrogenase (EC 1.5.99.8); E=1e-180 COG: jhp0048_2; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-123 Cj1503c_1; COG0506 Proline dehydrogenase; E=2e-56 sll1561_2; COG1012 NAD-dependent aldehyde dehydrogenases; E=1e-51 PFAM: PF01619; Proline dehydrogenase; E=2e-36 PF00171; Aldehyde dehydrogenase family; E=0.0014; Belongs to the aldehyde dehydrogenase family.
  
  
 0.885
RB3966
Hypothetical protein-transmembrane prediction.
       0.806
cstA
Carbon starvation-induced protein; PMID: 99411980 best DB hits: BLAST: ddbj:BAB05512.1; (AP001513) carbon starvation-induced protein; E=3e-82 swissprot:O67304; CSTA_AQUAE CARBON STARVATION PROTEIN A HOMOLOG; E=5e-65 pir:E75032; carbon starvation protein A homolog PAB1554 [similarity]; E=1e-53 COG: BH1793; COG1966 Carbon starvation protein, predicted membrane; E=3e-83 yjiY; COG1966 Carbon starvation protein, predicted membrane protein; E=2e-47 jhp1095; COG1966 Carbon starvation protein, predicted membrane; E=3e-47 PFAM: PF02554; Carbon starvation protein CstA; E=2.2e-104.
 
    0.744
RB5117
Cation/multidrug efflux pump; PMID: 8407802 best DB hits: BLAST: pir:F82829; acriflavin resistance protein XF0243 [imported] - Xylella; E=2e-88 pir:F82159; transporter, AcrBD/F family VC1757 [imported] - Vibrio; E=3e-86 pir:B83627; probable RND efflux transporter PA0158 [imported] -; E=6e-79 COG: XF0243; COG0841 Cation/multidrug efflux pump; E=2e-89 PFAM: PF00873; AcrB/AcrD/AcrF family; E=3e-15; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
     0.607
RB6538
Sodium/glucose cotransporter; PMID: 8652595 best DB hits: BLAST: swissprot:P31448; YIDK_ECOLI HYPOTHETICAL 62.1 KD PROTEIN IN; E=8e-94 gb:AAG58882.1; AE005599_14 (AE005599) putative cotransporter; E=2e-93 ddbj:BAB05941.1; (AP001514) Na+myo-inositol cotransporter; E=7e-87 COG: yidK; COG0591 Na+/proline, Na+/panthothenate symporters and related; E=8e-95 BH2222; COG0591 Na+/proline, Na+/panthothenate symporters and; E=7e-88 panF; COG0591 Na+/proline, Na+/panthothenate symporters and related; E=4e-11 PFAM: PF00474; Sodium:solute symporter family; E=2.8e-33; Belongs to the sodium:solute sym [...]
  
     0.601
acrD
Best DB hits: BLAST: pir:B83627; probable RND efflux transporter PA0158 [imported] -; E=9e-84 pir:F82829; acriflavin resistance protein XF0243 [imported] - Xylella; E=1e-81 pir:B82604; cation efflux system protein XF2083 [imported] - Xylella; E=6e-77 COG: PA0158; COG0841 Cation/multidrug efflux pump; E=8e-85 PFAM: PF00873; AcrB/AcrD/AcrF family; E=8.1e-17; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
     0.597
RB5641
Best DB hits: BLAST: pir:H81355; probable integral membrane protein Cj0832c [imported] -; E=2e-58 pir:D75220; hypothetical protein PAB2161 - Pyrococcus abyssi (strain; E=3e-54 pir:D71202; hypothetical protein PH1889 - Pyrococcus horikoshii; E=4e-52 COG: Cj0832c; COG1757 Na+/H+ antiporter; E=2e-59.
  
  
 0.576
RB3964
Hypothetical protein.
       0.572
RB8797
Sodium iodide symporter; PMID: 9329364 best DB hits: BLAST: pir:S75887; hypothetical protein - Synechocystis sp. (strain PCC; E=3e-31 embl:CAC16517.1; (AL450223) putative integral membrane transport; E=1e-27 gb:AAF57192.1; (AE003779) CG2187 gene product [Drosophila; E=6e-27 COG: sll1087; COG0591 Na+/proline, Na+/panthothenate symporters and; E=3e-32 yidK; COG0591 Na+/proline, Na+/panthothenate symporters and related; E=3e-06 PAB0609; COG0591 Na+/proline, Na+/panthothenate symporters and; E=1e-04 PFAM: PF00474; Sodium:solute symporter family; E=1.5e-11; Belongs to the sodium:solute symp [...]
  
     0.547
RB5116
Probable membrane-fusion protein; PMID: 8407802 best DB hits: BLAST: pir:F64826; probable membrane protein b0878 - Escherichia coli; E=4e-05 swissprot:P75830; YBJY_ECOLI HYPOTHETICAL 41.7 KDA PROTEIN IN; E=4e-05 gb:AAG55260.1; AE005269_4 (AE005269) putative membrane protein; E=7e-05 COG: ybjY; COG0845 Membrane-fusion protein; E=4e-06 VC1410; COG1566 Multidrug resistance efflux pump; E=0.008 PFAM: PF00364; Biotin-requiring enzyme; E=0.39.
  
     0.526
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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