STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB4043Probable glucose-1-phosphate thymidylyltransferase; Best DB hits: BLAST: pir:F72591; probable sugar phosphate transferase APE1202 - Aeropyrum; E=5e-11 pir:E71207; probable glucose-1-phosphate thymidylyltransferase -; E=3e-10 pir:G75020; glucose-1-phosphate thymidylyltransferase (grad-2); E=5e-10 COG: APE1202; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylases; E=5e-12 TM1629; COG1207 N-acetylglucosamine-1-phosphate uridyltransferase; E=4e-04 MJ1101; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylases; E=0.006. (451 aa)    
Predicted Functional Partners:
pmm
Phosphomannomutase; PMID: 8083177 best DB hits: BLAST: gb:AAD56627.1; AF165218_2 (AF165218) Pgm [Streptococcus; E=2e-83 ddbj:BAB04825.1; (AP001510) phosphomannomutase [Bacillus; E=5e-79 swissprot:P18159; YHXB_BACSU PROBABLE PHOSPHOMANNOMUTASE (PMM); E=1e-77 COG: BH1106; COG1109 Phosphomannomutase; E=5e-80 VC2095; COG0033 Phosphoglucomutase; E=3e-11 PH0923; COG1109 Phosphomannomutase; E=5e-11 PFAM: PF02878; Phosphoglucomutase/phosphomannomu; E=1.6e-13 PF02880; Phosphoglucomutase/phosphomannomu; E=0.023 PF00408; Phosphoglucomutase/phosphomannomu; E=0.76.
  
 
 0.914
rfbB
dTDP-glucose-4,6-dehydratase; PMID: 8022265 best DB hits: BLAST: gb:AAG35060.1; AF314183_2 (AF314183) dTDP-glucose-4,6-dehydratase; E=1e-110 gb:AAF33465.1; (AF233324) 89% identity with E. coli; E=1e-107 swissprot:P55294; RFBB_NEIMB DTDP-GLUCOSE 4,6-DEHYDRATASE -----; E=1e-106 COG: NMB0063; COG1088 dTDP-D-glucose 4,6-dehydratase; E=1e-107 PFAM: PF01073; 3-beta hydroxysteroid dehydro; E=0.53 PF00106; short chain dehydrogenase; E=0.073 PF01370; NAD dependent epimerase/dehyd; E=6e-141; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
    
 0.913
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.895
hasC
PMID: 7499387 best DB hits: BLAST: pir:A75096; UTP--glucose-1-phosphate uridylyltransferase (EC; E=3e-20 gb:AAD32398.1; AAD32398 (AF065404) pXO1-94 [Bacillus anthracis]; E=4e-19 swissprot:Q54713; HASC_STRPY UTP--GLUCOSE-1-PHOSPHATE; E=2e-17 COG: PAB0771; COG1210 UDP-glucose pyrophosphorylase; E=3e-21 PAB0784; COG1209 dTDP-glucose pyrophosphorylase; E=3e-04 PFAM: PF00483; Nucleotidyl transferase; E=0.014.
     
 0.828
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
  
 0.706
glmS
PMID: 7476196 best DB hits: BLAST: embl:CAB87226.1; (AL163641) glucosamine-fructose-6-phosphate; E=1e-135 pir:T44486; glutamine--fructose-6-phosphate transaminase; E=1e-133 gb:AAF09884.1; AE001891_3 (AE001891); E=1e-132 COG: DR0302; COG0449 Glucosamine 6-phosphate synthetase, contains; E=1e-133 PFAM: PF00310; Glutamine amidotransferases class-II; E=2.1e-65 PF01380; SIS domain; E=2.2e-39.
 
  
 0.618
RB9832
Phosphomannomutase (pmm); Best DB hits: BLAST: pir:E71082; probable phospho-sugar mutase 2 - Pyrococcus horikoshii; E=1e-60 pir:H75104; phosphomannomutase (pmm) PAB0819 - Pyrococcus abyssi; E=7e-58 gb:AAB90779.1; (AE001073) phosphomannomutase (pmm) [Archaeoglobus; E=5e-53 COG: PH0923; COG1109 Phosphomannomutase; E=1e-61 PFAM: PF02878; Phosphoglucomutase/phosphomannomu; E=4.1e-29 PF02879; Phosphoglucomutase/phosphomannomu; E=1.2e-15 PF02880; Phosphoglucomutase/phosphomannomu; E=0.00028.
 
  
 0.605
RB10799
Hypothetical protein-putative transmembrane protein.
  
    0.597
RB1954
Best DB hits: BLAST: pir:T30283; polyketide synthase - Streptomyces sp. (strain MA6548); E=0.11 gb:AAF86396.1; AF235504_17 (AF235504) FkbA [Streptomyces; E=0.11 pir:T30228; polyketide synthase - Streptomyces hygroscopicus -----; E=0.12.
  
     0.596
RB4046
Hypothetical protein.
       0.560
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.