STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
blaIProbable Penicillinase repressor; PMID: 3096969 PMID: 3305074 PMID: 3260234 best DB hits: BLAST: swissprot:P06555; BLAI_BACLI PENICILLINASE REPRESSOR (REGULATORY; E=7e-10 pir:B28183; beta-lactamase repressor protein - Bacillus; E=8e-09 pir:S74550; hypothetical protein slr0240 - Synechocystis sp. (strain; E=2e-05 PFAM: PF00392; Bacterial regulatory proteins, gntR; E=0.082. (147 aa)    
Predicted Functional Partners:
blaR
Probable regulatory protein blaR1; PMID: 3040663 PMID: 3260234 PMID: 2404938 best DB hits: BLAST: swissprot:P12287; BLAR_BACLI REGULATORY PROTEIN BLAR1 -----; E=2e-05 pir:I39942; penicillinase antirepressor penJ - Bacillus; E=5e-05 swissprot:P18357; BLAR_STAAU REGULATORY PROTEIN BLAR1 -----; E=3e-04 PFAM: PF01271; Granin (chromogranin or secretograni; E=0.87.
 
  
 0.961
RB7200
Probable penicillin resistance regulatory protein; PMID: 3040663 PMID: 3260234 PMID: 2404938 best DB hits: BLAST: swissprot:P12287; BLAR_BACLI REGULATORY PROTEIN BLAR1 -----; E=1e-12 pir:I39942; penicillinase antirepressor penJ - Bacillus; E=1e-11 swissprot:P26597; MECR_STAEP METHICILLIN RESISTANCE MECR1 PROTEIN; E=6e-05 PFAM: PF02687; Predicted permease; E=0.51.
 
  
 0.806
RB8441
PMID: 87307953 best DB hits: BLAST: pir:I39942; penicillinase antirepressor penJ - Bacillus; E=1e-07 swissprot:P12287; BLAR_BACLI REGULATORY PROTEIN BLAR1 -----; E=2e-07.
 
  
 0.805
RB756
Probable beta-lactamase regulatory protein; PMID: 3040663 PMID: 3260234 PMID: 2404938 best DB hits: BLAST: swissprot:P12287; BLAR_BACLI REGULATORY PROTEIN BLAR1 -----; E=7e-09 pir:I39942; penicillinase antirepressor penJ - Bacillus; E=8e-09 swissprot:P26597; MECR_STAEP METHICILLIN RESISTANCE MECR1 PROTEIN; E=4e-07.
 
  
 0.780
RB757
Similar to beta-lactamase repressor protein; PMID: 3096969 PMID: 3305074 PMID: 3260234 PMID: 3040663 PMID: 3498148 best DB hits: BLAST: swissprot:P06555; BLAI_BACLI PENICILLINASE REPRESSOR (REGULATORY; E=0.24 pir:B28183; beta-lactamase repressor protein - Bacillus; E=0.34 swissprot:P26598; MECI_STAEP METHICILLIN RESISTANCE REGULATORY; E=0.60.
  
     0.725
RB4115
Conserved hypothetical protein-putative nitrate reductase related protein; Best DB hits: BLAST: embl:CAC01558.1; (AL391039) conserved hypothetical protein; E=3e-27 gb:AAG19482.1; (AE005040) sulfite oxidase homolog; YuiH; E=3e-27 pir:A70013; sulfite oxidase homolog yuiH - Bacillus subtilis -----; E=6e-26 COG: VNG1084G; COG2041 Uncharacterized enzymes, related to nitrate; E=3e-28 sll1011_2; COG1357 Uncharacterized low-complexity proteins; E=1e-11 PA4692; COG2041 Uncharacterized enzymes, related to nitrate; E=2e-11 PFAM: PF00174; Oxidoreductase molybdopterin b; E=0.16 PF00805; Pentapeptid [...]
  
    0.656
RB9073
Conserved hypothetical protein containing TPR domain; Best DB hits: PFAM: PF00515; TPR Domain; E=0.83.
  
     0.641
RB3382
Best DB hits: BLAST: pir:E69078; conserved hypothetical protein MTH1585 -; E=0.28.
  
    0.625
RB13215
Hypothetical protein-putative transmembrane protein.
 
  
 0.593
RB9066
Similar to RTX family exoprotein; Best DB hits: BLAST: gb:AAG54838.1; AE005229_1 (AE005229) putative RTX family exoprotein; E=0.005 swissprot:Q99144; PEX5_YARLI PEROXISOMAL TARGETING SIGNAL RECEPTOR; E=0.056 pir:A72220; conserved hypothetical protein - Thermotoga maritima; E=0.084 COG: TM1695; COG0457 TPR-repeat-containing proteins; E=0.008 PFAM: PF00515; TPR Domain; E=0.28 PF01839; FG-GAP repeat; E=0.0027.
  
     0.590
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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