STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB4382Probable diaminopimelate decarboxylase; PMID: 6350601 PMID: 89056708 PMID: 94237165 best DB hits: BLAST: swissprot:P55709; Y4YA_RHISN HYPOTHETICAL 49.9 KD PROTEIN Y4YA; E=3e-40 gb:AAG45731.1; AF229441_2 (AF229441) y4yA [Sinorhizobium fredii]; E=3e-40 gb:AAG45729.1; AF229440_2 (AF229440) y4yA [Sinorhizobium fredii]; E=3e-33 COG: aq_728; COG0019 Diaminopimelate decarboxylase; E=7e-08 PA4839; COG1166 Arginine decarboxylase (spermidine biosynthesis); E=5e-05 XF1116_2; COG0019 Diaminopimelate decarboxylase; E=5e-05 PFAM: PF02784; Pyridoxal-dependent decarboxyla; E=5.9e-08. (555 aa)    
Predicted Functional Partners:
RB4383
Conserved hypothetical protein; Best DB hits: BLAST: gb:AAG56655.1; AE005390_2 (AE005390) orf, hypothetical protein; E=5e-05 swissprot:P77148; YDHS_ECOLI HYPOTHETICAL 60.8 KDA PROTEIN IN; E=1e-04.
     0.990
lysA
Hypothetical 49.9 kDa protein Y4YA-putative diaminopimelate decarboxylase; PMID: 9163424 best DB hits: BLAST: gb:AAG45731.1; AF229441_2 (AF229441) y4yA [Sinorhizobium fredii]; E=7e-30 swissprot:P55709; Y4YA_RHISN HYPOTHETICAL 49.9 KD PROTEIN Y4YA; E=3e-29 gb:AAG45729.1; AF229440_2 (AF229440) y4yA [Sinorhizobium fredii]; E=3e-26 COG: sll0504; COG0019 Diaminopimelate decarboxylase; E=7e-08 PFAM: PF02784; Pyridoxal-dependent decarboxyla; E=0.71.
  
  
 
0.914
murE
Probable UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase; PMID: 8436954 best DB hits: BLAST: swissprot:Q03523; MURE_BACSU; E=2e-10 ddbj:BAB06290.1; (AP001515); E=4e-09 swissprot:O86491; MURE_STAAU; E=7e-09 COG: BS_murE; COG0769 UDP-N-acetylmuramyl tripeptide synthase; E=2e-11 XF0794; COG0770 UDP-N-acetylmuramyl pentapeptide synthase; E=1e-09 CPn0418; COG0769 UDP-N-acetylmuramyl tripeptide synthase; E=2e-06 PFAM: PF01225; Mur ligase family, catalytic domai; E=0.0033 PF00023; Ank repeat; E=0.019.
     
 0.910
lysA-2
Diaminopimelate decarboxylase; PMID: 6350601 best DB hits: BLAST: gb:AAK05382.1; AE006360_11 (AE006360) diaminopimelate; E=1e-106 swissprot:P31851; TABA_PSESZ TABA PROTEIN ----- pir: S27649; E=6e-92 swissprot:O27390; DCDA_METTH DIAMINOPIMELATE DECARBOXYLASE (DAP; E=7e-59 COG: MTH1335; COG0019 Diaminopimelate decarboxylase; E=7e-60 PFAM: PF02784; Pyridoxal-dependent decarboxy; E=3.1e-40 PF00278; Pyridoxal-dependent decarboxy; E=1.4e-29.
     
  0.900
RB4386
Cysteine synthase; PMID: 93345669 best DB hits: BLAST: swissprot:Q44004; CYSM_ALCEU CYSTEINE SYNTHASE (O-ACETYLSERINE; E=2e-35 pir:T43792; cysteine synthase (EC 4.2.99.8) cysK [similarity] -; E=1e-31 pir:H81161; probable cysteine synthase (EC 4.2.99.8) NMA0974; E=3e-31 COG: NMB0763; COG0031 Cysteine synthase; E=2e-32 PFAM: PF00291; Pyridoxal-phosphate dependent enzyme; E=9.2e-57.
 
  
 0.851
kamA
L-lysine 2,3-aminomutase; Best DB hits: BLAST: pir:C82554; conserved hypothetical protein XF2474 [imported] -; E=7e-72 gb:AAG59345.1; AE005648_7 (AE005648) orf, hypothetical protein; E=4e-70 swissprot:P39280; YJEK_ECOLI HYPOTHETICAL 38.7 KD PROTEIN IN; E=1e-67 COG: XF2474; COG1509 Lysine 2,3-aminomutase; E=7e-73 PFAM: PF02587; Uncharacterized ACR, YjeK family COG; E=6e-109.
     
  0.800
RB4381
Hypothetical protein.
       0.773
RB4389
Hypothetical protein.
       0.773
RB4390
Conserved hypothetical protein; PMID: 9371463 best DB hits: BLAST: pir:H69043; conserved hypothetical protein MTH1330 -; E=0.004 swissprot:Q50500; YE63_METTH HYPOTHETICAL PROTEIN MTH1463 (ORF11); E=0.005 pir:A69088; conserved hypothetical protein MTH1653 -; E=0.010 COG: MTH1330; COG3271 Predicted double-glycine peptidase; E=4e-04.
       0.773
RB10608
Similar to transposase insG for insertion sequence element IS4; PMID: 11292750 best DB hits: BLAST: swissprot:P03835; YI41_ECOLI INSERTION ELEMENT IS4 HYPOTHETICAL; E=0.030 embl:CAA57483.1; (X81894) ORF [Enterobacter agglomerans]; E=0.064 COG: yi41; COG3385 Predicted transposase; E=0.003.
  
     0.617
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.