STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RB4399Quinone oxidoreductase; PMID: 7602590 best DB hits: BLAST: embl:CAB59716.1; (AL132707) putative zinc-binding oxidoreductase; E=3e-31 pir:T10203; hypothetical protein F25G13.100 - Arabidopsis thaliana; E=2e-28 embl:CAC14345.1; (AL445945) putative zinc-binding oxidoreductase; E=1e-26 COG: VC0552; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-26 PFAM: PF00107; Zinc-binding dehydrogenases; E=5.2e-48. (328 aa)    
Predicted Functional Partners:
RB4398
Hypothetical protein.
       0.773
RB4400
Hypothetical protein.
       0.773
RB6500
Mycocerosate synthase; PMID: 3880746 best DB hits: BLAST: pir:S72705; mycocerosate synthase (EC 2.3.1.111) - Mycobacterium; E=0.0 pir:H70819; probable polyketide synthase - Mycobacterium tuberculosis; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=1e-180 COG: PA2402_3; COG1020 Non-ribosomal peptide synthetase modules and related; E=4e-99 BS_ppsD_3; COG1020 Non-ribosomal peptide synthetase modules and; E=4e-92 PA2424_2; COG1020 Non-ribosomal peptide synthetase modules and related; E=1e-91 PFAM: PF00108; Thiolase, N-terminal domain; E=2.7e-06 PF00109; Beta-keto [...]
  
 
0.615
RB11975
Polyketide synthase; PMID: 10662695 PMID: 10649995 best DB hits: BLAST: gb:AAF26921.1; AF210843_18 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF26923.1; AF210843_20 (AF210843) polyketide synthase [Sorangium; E=0.0 gb:AAF62883.1; AF217189_6 (AF217189) epoD [Sorangium cellulosum]; E=0.0 COG: BS_fabD; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=7e-31 PA2965; COG0304 3-oxoacyl-(acyl-carrier-protein) synthase I; E=3e-28 PA5234; COG0604 NADPH:quinone reductase and related Zn-dependent; E=2e-27 PFAM: PF00108; Thiolase, N-terminal domain; E=7.3e-07 PF00109; Beta-ketoacyl s [...]
  
 
0.613
RB4402
Hypothetical protein.
       0.572
phoD-3
Alkaline phosphatase D [Precursor]; PMID: 8760916 PMID: 25878 best DB hits: BLAST: swissprot:P42251; PPBD_BACSU ALKALINE PHOSPHATASE D PRECURSOR; E=1e-124 ddbj:BAA06483.1; (D30808) unknown [Bacillus subtilis]; E=1e-110 pir:T50595; probable alkaline phosphatase [imported] - Streptomyces; E=1e-103.
 
      0.536
RB10446
Beta keto-acyl synthase; Best DB hits: BLAST: ddbj:BAA89384.1; (AB025342) ORF10 [Moritella marina]; E=3e-37 pir:T30185; hypothetical protein 7 - Shewanella sp ----- gb:; E=3e-36 pir:T37057; probable multi-domain beta keto-acyl synthase -; E=8e-35 COG: DR1945; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=3e-17 Rv3391_1; COG0451 Nucleoside-diphosphate-sugar epimerases; E=2e-14 BH2492; COG0331 (acyl-carrier-protein) S-malonyltransferase; E=2e-13 PFAM: PF00109; Beta-ketoacyl synthase, N-ter; E=7.7e-09 PF02801; Beta-ketoacyl synthase, C-ter; E=7.6e-61 PF00109; Beta-ketoacyl syntha [...]
  
 
 0.535
RB4404
Hypothetical oxidoreductase yhxD-putative dehydrogenase of the short-chain dehydrogenase family; Best DB hits: BLAST: swissprot:P40398; YHXD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN; E=2e-67 swissprot:P80873; GS39_BACSU GENERAL STRESS PROTEIN 39 (GSP39); E=3e-65 gb:AAG02162.1; AF212041_18 (AF212041) ribitol dehydrogenase; E=8e-65 COG: BS_yhxD; COG1028 Dehydrogenases with different specificities; E=2e-68 BH1511; COG1028 Dehydrogenases with different specificities (related; E=1e-64 DRA0364; COG1028 Dehydrogenases with different specificities; E=1e-62 PFAM: PF00106; short chain dehydrogenase; [...]
  
   0.511
RB386
Saframycin Mx1 synthetase B; PMID: 8936303 best DB hits: BLAST: pir:T18551; saframycin Mx1 synthetase B - Myxococcus xanthus -----; E=1e-112 pir:T34918; polyketide synthase - Streptomyces coelicolor -----; E=1e-102 pir:H83343; probable non-ribosomal peptide synthetase PA2424; E=1e-101 COG: PA2424_1; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid; E=1e-102 Rv1529; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases; E=7e-83 Ta1189; COG0156 7-keto-8-aminopelargonate synthetase and related; E=6e-62 PFAM: PF00501; AMP-binding enzyme; E=2.2e-08 PF00550; Phosphopantetheine attac [...]
  
  
 0.429
Your Current Organism:
Rhodopirellula baltica
NCBI taxonomy Id: 243090
Other names: Pirellula sp. 1, R. baltica SH 1, Rhodopirellula baltica SH 1, Rhodopirellula baltica str. SH 1, Rhodopirellula baltica strain SH 1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.